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CAS No 46464-11-3 , 1-[(4-methoxyphenyl)methyl]-2,3-dimethylguanidine

  • Name: 1-[(4-methoxyphenyl)methyl]-2,3-dimethylguanidine
  • Synonyms: AC1L28IV;1-[(4-methoxyphenyl)methyl]-2,3-dimethylguanidine; Meobentine [INN]; Meobentinum [INN-Latin];T6739104; Meobentina; SureCN309374; Meobentina [INN-Spanish]; Meobentinum;
  • CAS Registry Number:
  • Flash Point: 150.7°C
  • Boiling Point: 325.5°Cat760mmHg
  • Density: 1.04g/cm3
  • Refractive index: 1.521
  • Flash Point: 150.7°C
  • Molecular Weight: 207.27218
  • InchiKey: SPLVKBMIQSSFFN-UHFFFAOYSA-N
  • InChI: InChI=1S/C11H17N3O/c1-12-11(13-2)14-8-9-4-6-10(15-3)7-5-9/h4-7H,8H2,
    1-3H3,(H2,12,13,14)
  • Molecular Formula: C11H17N3O
  • Molecular Structure:CAS No:46464-11-3 1-[(4-methoxyphenyl)methyl]-2,3-dimethylguanidine

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References of 1-[(4-methoxyphenyl)methyl]-2,3-dimethylguanidine
Title: Meobentine
CAS Registry Number: 46464-11-3
CAS Name: N-[(4-Methoxyphenyl)methyl]-N￠,N￠￠-dimethylguanidine
Synonyms: 1-(p-methoxybenzyl)-2,3-dimethylguanidine
Molecular Formula: C11H17N3O
Molecular Weight: 207.27
Percent Composition: C 63.74%, H 8.27%, N 20.27%, O 7.72%
Literature References: Antidysrhythmic, antifibrillatory deriv of guanidine, q.v. Prepn of the sulfate: R. A. Maxwell, E. Walton, DE 2030693 corresp to US 3949089 (1971, 1976 both to Burroughs Wellcome). Antidysrhythmic effects and tissue concentration: K. B. Touw et al., Pharmacologist 19, 268 (1977); K. B. Touw, Diss. Abstr. B 39, 5340 (1979). Pharmacokinetics by radioimmunoassay: J. W. A. Findlay et al., Pharmacologist 21, 337 (1979). Pharmacological study: W. B. Wastila et al., J. Pharm. Pharmacol. 33, 594 (1981).
 
Derivative Type: Sulfate
CAS Registry Number: 58503-79-0
Trademarks: Rythmatine (Burroughs Wellcome)
Molecular Formula: (C11H17N3O)2.H2SO4
Molecular Weight: 512.62
Percent Composition: C 51.55%, H 7.08%, N 16.39%, O 18.73%, S 6.26%
Properties: Cryst, mp 273-274°.
Melting point: mp 273-274°
 
Therap-Cat: Antiarrhythmic (class III).
Keywords: Antiarrhythmic.