Home > Name List By other > (6R, 7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[(2-thiophen-2-ylacetyl)amino]- 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxyla... China

CAS No 50-59-9 , (6R,
7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[(2-thiophen-2-ylacetyl)amino]-
5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Search by region : China

  • Name: (6R,
    7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[(2-thiophen-2-ylacetyl)amino]-
    5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • Synonyms: Loridine; Cefaloridin;(6R,
    7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[(2-thiophen-2-ylacetyl)amino]-
    5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; Cefaloridinum; Cefalorizin; Cefaloridina; Cepaloridin; Cephaloridin; Cephaloridinum;cefaloridine;
  • CAS Registry Number:
  • Safety Statements: Experimental poison by intracerebral route. Moderately toxic to humans by intravenous route. Moderately toxic experimentally by ingestion, subcutaneous, intraperitoneal, and intravenous routes. Human systemic effects by intravenous route: nausea or vomiting and fatty liver degeneration. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of NOx and SOx.
  • EINECS: 200-052-6
  • Molecular Weight: 415.48598
  • InchiKey: CZTQZXZIADLWOZ-CRAIPNDOSA-N
  • InChI: InChI=1S/C19H17N3O4S2/c23-14(9-13-5-4-8-27-13)20-15-17(24)22-16(19(25)
    26)12(11-28-18(15)22)10-21-6-2-1-3-7-21/h1-8,15,18H,9-11H2,(H-,20,23,25,
    26)/t15-,18-/m1/s1
  • Molecular Formula: C19H17N3O4S2
  • Molecular Structure:CAS No:50-59-9 (6R,<br />7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[(2-thiophen-2-ylacetyl)amino]-<br />5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Related products

Select to

50-59-9 Pyridinium,1-[[(6R,7R)-2-carboxy-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-,inner salt

Contact Supplier

50-59-9 Cephaloridine

  • Cephaloridine
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,nullChina
Contact Supplier

50-59-9 Cefaloridine

  • Cefaloridine, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
Contact Supplier

50-59-9 Cefaloridine

  • Cefaloridine, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
Contact Supplier

50-59-9 Cefaloridine

Contact Supplier

50-59-9 Cefaloridine, 99.50%

Contact Supplier

Select to

1/1
References of (6R,
7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[(2-thiophen-2-ylacetyl)amino]-
5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Title: Cephaloridine
CAS Registry Number: 50-59-9
CAS Name: 1-[[(6R,7R)-2-Carboxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium inner salt
Synonyms: 1-[(7￠-b-[2-(2-thienyl)acetamido]-8￠-oxo-1￠-aza-5￠-thiabicyclo[4.2.0]oct-2￠-en-3￠-yl)methyl]pyridinium-2￠-carboxylate; N-[7-[(2-thienyl)acetamido]ceph-3-em-3-ylmethyl]pyridinium-4-carboxylate; N-[7-(2￠-thienylacetamidoceph-3-ylmethyl)]pyridinium-2-carboxylate; cefaloridin
Trademarks: Ceflorin (Glaxo); Cepaloridin (Glaxo); Cer (Nippon Glaxo); Faredina (Lafare); Ceporan (Glaxo); Ceporin (Glaxo); Cilifor (C.E.P.A.); Intrasporin (Torlan); Keflodin (Lilly); Keflordin (obsolete) (Lilly); Lloncefal (Castillon); Sefacin (Schering); Cepalorin; Deflorin (Glaxo); Kefspor (Lilly); Loridine (Lilly); Ampligram (Hermes); Floridin (Coli)
Molecular Formula: C19H17N3O4S2
Molecular Weight: 415.49
Percent Composition: C 54.92%, H 4.12%, N 10.11%, O 15.40%, S 15.43%
Literature References: Semi-synthetic cephalosporin antibiotic. Prepn: FR 1384197 (1965 to Glaxo), C.A. 63, 11591c (1965); E. H. Flynn, US 3449338 (1969 to Lilly). Toxicity studies: Atkinson et al., Toxicol. Appl. Pharmacol. 8, 398 (1966).
Properties: Crystals. Soluble in water. Aq solns are slightly acid (pH 4.5-5); [a]D +47.7° (c = 1.25 in water). uv max: 239, 252 nm (e 15160, 13950). pKa 3.2. Aq solns (20% w/v) are stable for four weeks at 4° in the dark. Exposure to sunlight causes discoloration. LD50 mice, rats (g/kg): >15, 2.5-4 orally; in monkeys (g/kg): >0.2 i.m. (Atkinson).
pKa: pKa 3.2
Optical Rotation: [a]D +47.7° (c = 1.25 in water)
Absorption maximum: uv max: 239, 252 nm (e 15160, 13950)
Toxicity data: LD50 mice, rats (g/kg): >15, 2.5-4 orally; in monkeys (g/kg): >0.2 i.m. (Atkinson)
Therap-Cat: Antibacterial.
Therap-Cat-Vet: Antibacterial.
Keywords: Antibacterial (Antibiotics); ?Lactams; Cephalosporins.