Home > Name List By 5 > 5-fluoro-1-[(2R,4S, 5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

CAS No 50-91-9 , 5-fluoro-1-[(2R,4S,
5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

  • Name: 5-fluoro-1-[(2R,4S,
    5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
  • Synonyms: Floxuridin; FUDR; Fluorodeoxyuridine; Deoxyfluorouridine;5-fluoro-1-[(2R,4S,
    5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione; 50-91-9;2'-Deoxy-5-fluorouridine; Fluoruridine deoxyribose; 5-Fluorodeoxyuridine;
  • CAS Registry Number:
  • Transport: UN 2811
  • Melting Point: 148-153 ºC
  • Density: 1.64 g/cm3
  • Refractive index: 1.608
  • Alpha: 35.9 º (C=1, WATER)
  • Safety Statements: R22;R36/37/38;R68
  • Hazard Symbols: Xn: Harmful;
  • EINECS: 200-072-5
  • Molecular Weight: 246.192443
  • InchiKey: ODKNJVUHOIMIIZ-RRKCRQDMSA-N
  • InChI: InChI=1S/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,
    5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
  • Risk Statements: S26;S36/37/39
  • Molecular Formula: C9H11FN2O5
  • Molecular Structure:CAS No:50-91-9 5-fluoro-1-[(2R,4S,<br />5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
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50-91-9 2'-Deoxy-5-FluoroUridine (FUDR)

  • United States Tecoland Corporation null
  • Tel: +1-(732)-603-9577
  • Fax: +1-(732)-906-1522
  • Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428, null,nullUnited States
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50-91-9 2''-DEOXY-5-FLUOROURIDINE 98%

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50-91-9 5-Fluoro-2'-deoxyuridine

  • 5-Fluoro-2'-deoxyuridine
  • China Hangzhou Pharma & Chem Co., Ltd. [Manufacturer]
  • Tel: +86 571 87040515
  • Fax: +86 571 87214761
  • Address: Hangzhou Pharma & Chem Co., Ltd.
    139 Qingchun Road, Hangzhou City,
    Zhejiang, China 310003 null,nullChina
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50-91-9 Floxuridine

  • Floxuridine
  • United States LKT Laboratories, Inc [Manufacturer]
  • Tel: (888)-558-5227
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  • Address: 2233 University Ave. West 55114-1600 St. PaulUNITED STATES 55114-1600 St. Paul,nullUnited States
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50-91-9 FUDR

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50-91-9 2''-DEOXY-5-FLUOROURIDINE

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50-91-9 5-FLURO-2-DEOXYURIDINE

  • 5-FLURO-2-DEOXYURIDINE
  • India Sisco Research Laboratories Pvt. Ltd. [Manufacturers]
  • Tel: +91 22 26872601
  • Fax: +91 22 26872681
  • Address: 2/F, Satam Industrial Estate, 'C' Wing, 2nd floor,Dr. Cardinal Gracious Road,Andheri (E), Mumbai - 400 099.Maharashtra, India. Mumbai,MumbaiIndia
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50-91-9 5-FLUORO-2''-DEOXYURIDINE

  • United States ChemContract Research Inc. [Manufacturer]
  • Tel: 714-732-8549
  • Fax: 714-464-4356
  • Address: ChemContract Research, Inc.
    20914 Cabrillo Lane Suite53
    Huntington Beach, CA 92646 null,nullUnited States
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50-91-9 (+)-5-Fluoro-2'-deoxyuridine

  • China Hangzhou Pharma & Chem Co.,Ltd. [Manufacturers]
  • Tel: +86-571-87040515
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  • Address: Rm.1201,QinglianBldg.No,139QingchunRd,HangzhouCity,Zhejiang,China Hangzhou,ZhejiangChina
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50-91-9 2''-DEOXY-5-FLUOROURIDINE (FLOXURIDINE)

  • United States NetQem, LLC [Manufacturer]
  • Tel: (919) 544-4122
  • Fax: (919) 544-4109
  • Address: NetQem, LLC
    P.O. Box 12091
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    NC 27709, USA null,nullUnited States
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References of 5-fluoro-1-[(2R,4S,
5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Title: Floxuridine
CAS Registry Number: 50-91-9
CAS Name: 2¢-Deoxy-5-fluorouridine
Synonyms: 1-(2-deoxy-b-D-ribofuranosyl)-5-fluorouracil; 5-fluoro-2¢-deoxy-b-uridine
Manufacturers' Codes: NSC-27640
Trademarks: FUDR (Roche)
Molecular Formula: C9H11FN2O5
Molecular Weight: 246.19
Percent Composition: C 43.91%, H 4.50%, F 7.72%, N 11.38%, O 32.49%
Literature References: Prepn: Hoffer et al., J. Am. Chem. Soc. 81, 4112 (1959); Heidelberger, Duschinsky, US 2885396 (1959); Duschinsky et al., US 2970139 (1961); Hoffer, US 2949451; US 3041335 (1960, 1962 both to Hoffmann-La Roche). Structure: Lemieux, Hoffer, Can. J. Chem. 39, 110 (1961). Crystal and molecular structure: Harris, Diss. Abstr. 24, 4425 (1964); Harris, McIntyre, Biophys. J. 4, 203 (1964). Conformation of furanose ring in molecule: Sundaralingam, J. Am. Chem. Soc. 87, 599 (1965).
Properties: Crystals from butyl acetate, mp 150-151° (Hoffer, 1959); also reported as mp 145° (US 3041335). [a]D +37° (water), +48.6° (DMF). uv max (pH 7.2): 268 nm (e 7570); (pH 14): 270 nm (e 6480).
Melting point: mp 150-151° (Hoffer, 1959); mp 145° (US 3041335)
Optical Rotation: [a]D +37° (water), +48.6° (DMF)
Absorption maximum: uv max (pH 7.2): 268 nm (e 7570); (pH 14): 270 nm (e 6480)
 
Derivative Type: a-Anomer
Synonyms: 1-(2-Deoxy-a-D-erythro-pentofuranosyl)-5-fluorouracil
Properties: Crystals from butyl acetate, mp 150-151°. [a]D25 -21° (c = 2 in water).
Melting point: mp 150-151°
Optical Rotation: [a]D25 -21° (c = 2 in water)
 
Therap-Cat: Antiviral; antineoplastic.
Keywords: Antineoplastic; Antimetabolites; Pyrimidine Analogs; Antiviral; Purines/Pyrimidinones.