Home > Name List By other > [2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate

CAS No 52365-63-6 , [2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl]
2,2-dimethylpropanoate

  • Name: [2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl]
    2,2-dimethylpropanoate
  • Synonyms: [2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl]
    2,2-dimethylpropanoate;Dipivefrine; dipivalyl epinephrine; Dipivefrinum; Dipivefrina; Dipivefrin [USAN]; Propine; Dipivefrinum [INN-Latin];
  • CAS Registry Number:
  • Density: 1.097 g/cm3
  • Refractive index: 1.511
  • Molecular Weight: 351.43726
  • InchiKey: OCUJLLGVOUDECM-UHFFFAOYSA-N
  • InChI: InChI=1S/C19H29NO5/c1-18(2,
    3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)25-17(23)19(4,5)6/h8-10,13,
    20-21H,11H2,1-7H3
  • Molecular Formula: C19H29NO5
  • Molecular Structure:CAS No:52365-63-6 [2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl]<br />2,2-dimethylpropanoate
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52365-63-6 DIPIVEFRINE

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong ,Hong kong
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52365-63-6 Dipivefrine

  • IUPAC NAME-[2-(2,2-dimethylpropanoyloxy)-4- (1-hydroxy-2-methylamino-ethyl)- phenyl] 2,2-dimethylpropanoate MOLECULAR FORMULA-C19H29NO5 MOLAR MASS-351.437 g/mol
  • India Swapnroop Drugs & Pharmaceuticals [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: 91-240-6641875
  • Fax: 91-240-6641870
  • Address: Plot No: 04, Mayur Park Road, Harsool Aurangabad,MaharashtraIndia

52365-63-6 Dipivefrine

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52365-63-6 Propanoic acid,2,2-dimethyl-, 1,1'-[4-[1-hydroxy-2-(methylamino)ethyl]-1,2-phenylene] ester

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52365-63-6 Propanoic acid,2,2-dimethyl-, 1,1'-[4-[1-hydroxy-2-(methylamino)ethyl]-1,2-phenylene] ester

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52365-63-6 DIPIVEFRIN

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 ,United States
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52365-63-6 DIPIVEFRINE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China ,China
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References of [2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl]
2,2-dimethylpropanoate
Title: Dipivefrin
CAS Registry Number: 52365-63-6
CAS Name: 2,2-Dimethylpropanoic acid 4-[1-hydroxy-2-(methylamino)ethyl]-1,2-phenylene ester
Synonyms: (±)-3,4-dihydroxy-a-[(methylamino)methyl]benzyl alcohol 3,4-dipivalate; 1-(3¢,4¢-dipivaloyloxyphenyl)-2-methylamino-1-ethanol; dipivalyl epinephrine; DPE
Molecular Formula: C19H29NO5
Molecular Weight: 351.44
Percent Composition: C 64.93%, H 8.32%, N 3.99%, O 22.76%
Literature References: Dipivalyl ester of epinephrine, q.v. Prepn: D. Henschler et al., DE 2152058; eidem, US 4085270 (1973, 1978 both to Klinge); A. Hussain, J. E. Truelove, DE 2343657; eidem, US 3809714 and US 3839584 (all 1974 to Interx). In vitro study: A. H. Neufeld, E. D. Page, Invest. Ophthalmol. Visual Sci. 16, 1118 (1977). Pharmacology: B. C. Wang et al., J. Pharmacol. Exp. Ther. 203, 442 (1977). Effects on intraocular pressure in dogs: R. M. Gwin et al., Am. J. Vet. Res. 39, 83 (1978). Metabolism: I. Abramovsky, J. S. Mindel, Arch. Ophthalmol. 97, 1937 (1979). Clinical study: M. A. Kass et al., ibid. 1865. General pharmacology, toxicology and clinical experience in glaucoma: D. A. McClure, ACS Symp. Ser. 14, 224-235 (1975). Comprehensive description: G. M. Wall, T. Y. Fan, Anal. Profiles Drug Subs. Excip. 22, 229-262 (1993).
Properties: Crystals from ether, mp 146-147°.
Melting point: mp 146-147°
 
Derivative Type: Hydrochloride
CAS Registry Number: 64019-93-8
Trademarks: Diopine (Allergan); d Epifrin (Allergan); Diphemin (Alcon); Pivalephrine (Santen); Propine (Allergan)
Molecular Formula: C19H29NO5.HCl
Molecular Weight: 387.90
Percent Composition: C 58.83%, H 7.80%, N 3.61%, O 20.62%, Cl 9.14%
Properties: Crystals from ethyl acetate, mp 158-159°. Sol in water and ethanol. pKa 8.40.
Melting point: mp 158-159°
pKa: pKa 8.40
 
Therap-Cat: Adrenergic (ophthalmic); antiglaucoma.
Keywords: a-Adrenergic Agonist; Antiglaucoma.