Title:  N-Hydroxyphthalimide
CAS Registry Number:  524-38-9
CAS Name:  2-Hydroxy-1
H-isoindole-1,3(2
H)-dione
Synonyms:  NHPI
Molecular Formula:  C8H5NO3
Molecular Weight:  163.13
Percent Composition:  C 58.90%, H 3.09%, N 8.59%, O 29.42%
Literature References:  Mediates oxidative catalytic transformations of organic compounds with molecular oxygen.  Prepn:  L. Cohn, 
Ann. 205, 295 (1880); H. Gross, I. Keitel, 
J. Prakt. Chem. 311, 692 (1969).  Crystal structure:  F.-M. Miao 
et al., Acta Crystallogr. C51, 712 (1995).  Transition metal free oxidation reactions:  C. Einhorn 
et al., Chem. Commun. 1997, 447; epoxidation of alkenes:  T. Iwahama 
et al., Heterocycles 52, 693 (2000).  Transition metal cocatalysis in alkane oxidation:  Y. Ishii 
et al., J. Org. Chem. 61, 4520 (1996); in hydroxylation of fatty acids:  M. A. Oakley 
et al., J. Mol. Catal. A 150, 105 (1999).  Description of catalytic mechanisms:  Y. Ishii, S. Sakaguchi, 
Catal. Surv. Jpn. 3, 27 (1999).
Properties:  Yellowish needles from water, mp 227-229°.  Also reported as colorless monoclinic crystals from water. d 1.59 mg m-3.
Melting point:  mp 227-229°
Density:  d 1.59 mg m-3
Use:  Catalyst for oxidation reactions.