Home > Name List By other > (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6, 8-tetraenoic acid

CAS No 5300-03-8 , (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,
8-tetraenoic acid

  • Name: (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,
    8-tetraenoic acid
  • Synonyms: 9-CIS-RETINOIC ACID; Panretin; 9(Z)-Retinoic acid; 9-cis Retinoic Acid; Panrexin; Panretyn;(2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,
    8-tetraenoic acid; (9cis)-retinoic acid; 9-cis-Tretinoin;
  • CAS Registry Number:
  • Density: 1.011 g/cm3
  • Safety Statements: R36/37/38;R61
  • Hazard Symbols: T: Toxic;
  • Molecular Weight: 300.43512
  • InchiKey: SHGAZHPCJJPHSC-ZVCIMWCZSA-N
  • InChI: InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20
    (18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8-,
    16-14+
  • Risk Statements: S26;S36/37/39;S45;S53
  • Molecular Formula: C20H28O2
  • Molecular Structure:CAS No:5300-03-8 (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,<br />8-tetraenoic acid
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5300-03-8 Retinoic acid, 9-cis-

  • China Watson International Ltd. []
  • Tel: +86-(512)-55117610
  • Fax: +86-(512)-55117630
  • Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332, ,China
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5300-03-8 RETINOIC ACID 9-cis-(RG)

  • RETINOIC ACID 9-cis-(RG)
  • United States ChromaDex Inc. [Manufacturer]
  • Tel: 949-419-0288
  • Fax: 949-419-0294
  • Address: ChromaDex Inc.
    10005 Muirlands Blvd. Suite G - First Floor
    Irvine, CA 92618 ,United States
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5300-03-8 9-cis-Retinoic Acid

  • China Kouting Chemical Co.,Ltd [Importer/Exporter]
  • Tel: +86-(21)-58116473
  • Fax: +86-(21)-61094103
  • Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318, shanghai,shanghaiChina
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5300-03-8 9-cis-Retinoic Acid

  • China Xilin Chemical Group Co., Ltd []
  • Tel: +86-(0)-15527136576
  • Fax: +86-(27)-83820093
  • Address: 16# Luojiashan, Wuchang District, Wuhan, Hubei 430071, ,China
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5300-03-8 RETINOIC ACID(9-CIS-)

  • United States Richman Chemical, Inc. [Manufacturer]
  • Tel: 215-628-2946
  • Fax: 215-628-4262
  • Address: Richman Chemical, Inc.
    768 North Bethlehem Pike
    Lower Gwynedd, PA 19002 ,United States
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5300-03-8 9-cis-Retinoic acid

  • 9-cis-Retinoic acid
  • United States LKT Laboratories, Inc [Manufacturer]
  • Tel: (888)-558-5227
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  • Address: 2233 University Ave. West 55114-1600 St. PaulUNITED STATES 55114-1600 St. Paul,United States
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5300-03-8 9-cis Retinoic acid

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5300-03-8 9-cis-Retinoic Acid

  • United States Richman Chemical Inc. [Importer/Exporter]
  • Tel: +1-(215)-628-2946
  • Fax: +1-(215)-628-4262
  • Address: 768, North Bethlehem Pike, Lower Gwynedd, Pennsylvania 19002, Lower Gwynedd,PAUnited States
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5300-03-8 9-cis-Retinoic Acid

  • China Hong Kong Beautart Biochem Co., Ltd. []
  • Tel: +86-(755)-84813563
  • Fax: +86-(755)-84813563
  • Address: Room 508, 5/F, 51 Liuwu Rd, Liuwu Village, Longgang District, Shenzhen 518118, ,China
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5300-03-8 Retinoic acid, 9-cis-

  • China Ningbo Highpharm Chem & Indu Co., Ltd [Manufacturers]
  • Tel: +86-574-27865011
  • Fax: +86-574-27865033
  • Address: Rm417,Shijilongteng Bldg, No.269 Zhongxing Rd,Ningbo China Ningbo,zhejiangChina
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References of (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,
8-tetraenoic acid
Title: Alitretinoin
CAS Registry Number: 5300-03-8
CAS Name: 9-cis-Retinoic acid
Synonyms: 6-cis-retinoic acid
Manufacturers' Codes: ALRT-1057; LGD-1057
Trademarks: Panretin (Ligand)
Molecular Formula: C20H28O2
Molecular Weight: 300.44
Percent Composition: C 79.95%, H 9.39%, O 10.65%
Literature References: Naturally occurring derivative of vitamin A, q.v. Morphogenic agent that modulates cell growth and differentiation; activates both retinoic acid (RAR) and retinoid X (RXR) receptors. Prepn: C. D. Robeson et al., J. Am. Chem. Soc. 77, 4111 (1955); M. Matsui et al., J. Vitaminol. 4, 178 (1958); M. F. Boehm et al., J. Med. Chem. 37, 408 (1994). Identification as physiological ligand of RXR: R. A. Heyman et al., Cell 68, 397 (1992); A. A. Levin et al., Nature 355, 359 (1992). Role in morphogenesis: C. Thaller et al., Development 118, 957 (1993). Biosynthesis from all-trans-retinoic acid: J. Urbach, R. R. Rando, Biochem. J. 299, 459 (1994). HPLC determn in plasma: A. M. Dzerk et al., J. Pharm. Biomed. Anal. 16, 1013 (1998). Clinical pharmacokinetics: C. Weber, E. Dumont, J. Clin. Pharmacol. 37, 566 (1997). Clinical evaluation in acute promyelocytic leukemia: S. L. Soignet et al., Leukemia 12, 1518 (1998); in advanced cancers: N. A. Rizvi et al., Clin. Cancer Res. 4, 1437 (1998). Review of role as hormone: B. F. Tate et al., Trends Endocrinol. Metab. 5, 189-194 (1994); of clinical development: J. Cell. Biochem. Suppl. 26, 158-167 (1996).
Properties: Yellow fine needles from ethanol, mp 190-191°. uv max (methanol): 343 nm (e 39000).
Melting point: mp 190-191°
Absorption maximum: uv max (methanol): 343 nm (e 39000)
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Retinoids and Analogs.