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CAS No 53003-10-4 , Salinomycin

  • Name: Salinomycin
  • Synonyms: (2r)-2-((5s)-6-{5-((10s,12r)-2-((6s,5r)-5-ethyl-5-hydroxy-6-methylperhydro-2h-pyran-2-yl)-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro(4.1.5.3)pentadec-13-en-9-yl)(1s,2s,3s,5r)-2-hydroxy-1,3-dimethyl-4-oxoheptyl}-5-methylperhydro-2h-pyran-2-yl)butanoic acid;(2R)-2-((5S)-6-{5-[(10S,12R)-2-((6S,5R)-5-Ethyl-5-hydroxy-6-methylperhydro-2H-pyran-2-yl)-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.5.3]pentadec-13-en-9-yl](1S,2S,3S,5R)-2-hydroxy-1,3-dimethyl-4-oxoheptyl}-5-methylperhydro-2H-pyran-2-yl)butanoic acid;Salinomycin;
  • CAS Registry Number:
  • Transport: UN 3462
  • Melting Point: 112.5-113.5 ºC
  • Density: 1.18 g/cm3
  • Water Solubility: Soluble in ethanol
  • Safety Statements: R25
  • Hazard Symbols: T: Toxic;
  • EINECS: 258-290-1
  • Molecular Weight: 751.01
  • InChI: InChI=1/C42H70O11/c1-11-29(38(46)47)31-15-14-23(4)36(50-31)27(8)34(44)26(7)35(45)30(12-2)37-24(5)22-25(6)41(51-37)19-16-32(43)42(53-41)21-20-39(10,52-42)33-17-18-40(48,13-3)28(9)49-33/h16,19,23-34,36-37,43-44,48H,11-15,17-18,20-22H2,1-10H3,(H,46,47)/t23-,24-,25+,26-,27-,28-,29+,30-,31?,32+,33+,34+,36+,37-,39-,40+,41+,42+/m0/s1
  • Risk Statements: S45
  • Molecular Formula: C42H70O11
  • Molecular Structure:CAS No:53003-10-4 Salinomycin
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53003-10-4 Salinomycin

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53003-10-4 Salinomycin

  • China YST PHARM [Manufacturers]
  • Tel: 86-311-85322916
  • Fax: 86-311-85322918
  • Address: No.266 Tianshan Street Hi-Tech District Shijiazhuang, China Shijiazhuang,HebeiChina
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53003-10-4 Salinomycin

  • China Starview International Limited [Manufacturers]
  • Tel: 86-571-88925295 88218645 88920965
  • Fax: 0086-571-88218645
  • Address: 2ND FLOOR, NO.111, YUYUN ROAD, HANGZHOU, ZHEJIANG, CHINA HANGZHOU,ZHEJIANGChina
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53003-10-4 Salinomycin

  • China Moon Chemical Ltd []
  • Tel: +86-(574)-27666863
  • Fax: +86-(574)-27668686, 27668810
  • Address: Floor 21,Building 11,Xintiandi,No.689, Shiji Road, Ningbo, Zhejiang 315040, ,China
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53003-10-4 Salinomycin

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53003-10-4 Salinomycin

  • China Wuhan ?Yuancheng Technology [, Manufacturer, Trading Company]
  • Tel: 86-028-88082911
  • Fax: 86-027-88048077
  • Address: 496#Zhongshan Road, Wuhan wuhan,hubeiChina
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53003-10-4 Salinomycin Sodium

  • China Zhejiang Shenghua Biok Biology Co., Ltd. [Manufacturers]
  • Tel: +86-(571)-8778 8551, 8778 8552
  • Fax: +86-(571)-8778 8550
  • Address: Zhongguan Industrial Park, Deqing, Zhejiang 313220, Hangzhou,ZhejiangChina
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53003-10-4 Salinomycin

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53003-10-4 Salinomycin

  • China Zhejiang Shenghua Biok Biology Co.,Ltd. [Manufacturers]
  • Tel: 86 572 8677097 / 86 572 8402869
  • Fax: 86 572 8402988
  • Address: Zhongguan Industrial Park, Deqing, Zhejiang, 313220 China Deqing,ZhejiangChina
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53003-10-4 Salinomycin

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References of Salinomycin
Title: Salinomycin
CAS Registry Number: 53003-10-4
Molecular Formula: C42H70O11
Molecular Weight: 751.00
Percent Composition: C 67.17%, H 9.39%, O 23.43%
Literature References: Polyether ionophoric antibiotic having a unique tricyclic spiroketal ring system and an unsaturated 6-membered ring in the molecule. Produced by a strain of Streptomyces albus (FERM-P No. 419 and ATCC 21838). Production: Y. Miyazaki et al., JP Kokai 72 25392 (1972 to Kaken Chem.), C.A. 78, 41561 (1973). Structure: H. Kinashi et al., Tetrahedron Lett. 1973, 4955. Taxonomy, production, isolation and physicochemical and biological properties: Y. Miyazaki et al., J. Antibiot. 27, 814 (1974). Use as a coccidiostat: Y. Tanaka et al., DE 2253031; eidem, US 3857948 (1973, 1974 to Kaken Chem.). Anticoccidial efficacy: T. T. Migaki et al., Poult. Sci. 58, 1192 (1979). Total synthesis: Y. Kishi et al., Front. Chem., Plenary Keynote Lect. IUPAC Congr., 28th 1981, K. J. Laidler, Ed. (Pergamon, Oxford, 1982) pp 287-304; R. C. D. Brown, P. J. Kocienski, Synlett 1994, 415, 417. HPLC determn in animal feeds: M. R. LaPointe, H. Cohen, J. Assoc. Off. Anal. Chem. 71, 480 (1988).
Properties: mp 112.5-113.5°. pKa¢ 6.4 (DMF). [a]D25 -63° (c = 1 in ethanol). uv max (ethanol-water, 2:1): 284 nm (e 126). LD50 in mice (mg/kg): 18 i.p.; 50 orally (Miyazaki).
Melting point: mp 112.5-113.5°
pKa: pKa¢ 6.4 (DMF)
Optical Rotation: [a]D25 -63° (c = 1 in ethanol)
Absorption maximum: uv max (ethanol-water, 2:1): 284 nm (e 126)
Toxicity data: LD50 in mice (mg/kg): 18 i.p.; 50 orally (Miyazaki)
 
Derivative Type: Sodium salt
CAS Registry Number: 55721-31-8
Trademarks: Bio-Cox (Alpharma); Sacox (Intervet); Salocin (Intervet)
Molecular Formula: C42H69NaO11
Molecular Weight: 772.98
Percent Composition: C 65.26%, H 9.00%, Na 2.97%, O 22.77%
Properties: mp 140-142°. [a]D25 -37° (c = 1 in ethanol).
Melting point: mp 140-142°
Optical Rotation: [a]D25 -37° (c = 1 in ethanol)
 
Therap-Cat-Vet: Anticoccidial agent.