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CAS No 55134-13-9 , Salinomycin, 4-methyl-,(4S)-

  • Name: Salinomycin, 4-methyl-,(4S)-
  • Synonyms: C 7819B;Salinomycin, 4-methyl-,(4S)-; Narasul; Antibiotic A 28086A; Antibiotic C 7819B;Monteban; Narasin A; Narasin;1,6,8-Trioxadispiro[4.1.5.3]pentadecane,salinomycin deriv.; A 28086A;
  • CAS Registry Number:
  • Transport: UN 2811 6.1/PG 2
  • Melting Point: 765.025
  • Flash Point: 242.3°C
  • Boiling Point: 842.5°C at 760 mmHg
  • Density: 1.17g/cm3
  • Refractive index: 1.545
  • Safety Statements: When heated to decomposition it emits acrid smoke and irritating fumes.
  • Hazard Symbols: T+
  • Flash Point: 242.3°C
  • Molecular Weight: 765.03
  • InchiKey: VHKXXVVRRDYCIK-CWCPJSEDSA-N
  • InChI: InChI=1S/C43H72O11/c1-12-30(35(46)27(8)34(45)28(9)36-23(4)21-24(5)37(51-36)31(13-2)39(47)48)38-25(6)22-26(7)42(52-38)18-15-32(44)43(54-42)20-19-40(11,53-43)33-16-17-41(49,14-3)29(10)50-33/h15,18,23-34,36-38,44-45,49H,12-14,16-17,19-22H2,1-11H3,(H,47,48)/t23-,24-,25-,26+,27-,28-,29-,30-,31+,32+,33+,34+,36+,37+,38-,40-,41+,42-,43-/m0/s1
  • Risk Statements: 28
  • Molecular Formula: C43H72O11
  • Molecular Structure:CAS No:55134-13-9 Salinomycin, 4-methyl-,(4S)-
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55134-13-9 Salinomycin, 4-methyl-,(4S)-

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi null,ShanXiChina
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55134-13-9 NARASIN

  • China HANGZHOU THINK CHEMICAL CO. [Manufacturer]
  • Tel: +86-571-81956191/ +86-571-81956192
  • Fax: +86-571-81956190
  • Address: 425 MOGAN HILL ROAD ,
    HANGZHOU, 310011 CHINA null,nullChina
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55134-13-9 Narasin

  • United States CBSCHEM LIMITED null
  • Fax: (888) 557-9843
  • Address: 621 South 48th Street, Suite 115,Tempe, AZ 85281 null,nullUnited States
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55134-13-9 NARASIN

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55134-13-9 NARASIN FROM STREPTOMYCES AURIOFACIENS

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of Salinomycin, 4-methyl-,(4S)-
Title: Narasin
CAS Registry Number: 55134-13-9
CAS Name: (4S)-4-Methylsalinomycin
Synonyms: narasin A
Manufacturers' Codes: Compd 79891; Antibiotic A-28086 factor A; C-7819B
Trademarks: Monteban (Elanco)
Molecular Formula: C43H72O11
Molecular Weight: 765.03
Percent Composition: C 67.51%, H 9.49%, O 23.00%
Literature References: Main component of a polyether antibiotic complex produced by Streptomyces aureofaciens NRRL 5758 & NRRL 8092. Production: D. H. Berg et al., DE 2525095 corresp to US 4038384 (1975, 1977 to Lilly); L. D. Boeck et al., Dev. Ind. Microbiol. 18, 471 (1976). Isoln and characterization: D. H. Berg, R. L. Hamill, J. Antibiot. 31, 1 (1978). Biosynthetic studies using 13C-NMR study: D. E. Dorman et al., Helv. Chim. Acta 59, 2625 (1976). Structure: J. L. Occolowitz et al., Biomed. Mass Spectrom. 3, 272 (1976); H. Seto et al., J. Antibiot. 30, 530 (1977). Anticoccidial activity: M. D. Ruff et al., Poult. Sci. 59, 2008 (1980). Total synthesis: Y. Kishi et al., Front. Chem., Plenary Keynote Lect. IUPAC Congr., 28th 1981, K. J. Laidler, Ed. (Pergamon, Oxford, 1982) pp 287-304. HPLC determn in animal feeds: M. R. LaPointe, H. Cohen, J. Assoc. Off. Anal. Chem. 71, 480 (1988).
Properties: Crystals from acetone-water, mp 98-100°; resolidif and remelts at 198-200°. uv max (ethanol): 285 nm (e 58). [a]D25 -54° (c = 0.2 in methanol). pKa 7.9 (80% aq DMF). Sol in alcohols, acetone, DMF, DMSO, benzene, chloroform, ethyl acetate. Insol in water. LD50 i.p. in mice: 7.15 mg/kg (Berg).
Melting point: mp 98-100°
pKa: pKa 7.9 (80% aq DMF)
Optical Rotation: [a]D25 -54° (c = 0.2 in methanol)
Absorption maximum: uv max (ethanol): 285 nm (e 58)
Toxicity data: LD50 i.p. in mice: 7.15 mg/kg (Berg)
Therap-Cat-Vet: Coccidiostat; growth stimulant.