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CAS No 53902-12-8 , 2-[[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino]benzoic acid

  • Name: 2-[[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino]benzoic acid
  • Synonyms: 3,4-DAA; Tranilastum;Rizaben; SB-252218; S1439_Selleck; Tranilastum [INN-Latin]; 53902-12-8;2-[[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino]benzoic acid; Rizaben (TN);
  • CAS Registry Number:
  • Melting Point: 166-168 ºC
  • Flash Point: 585.6 °C at 760 mmHg
  • Boiling Point: 585.6 °C at 760 mmHg
  • Density: 1.299 g/cm3
  • Refractive index: 1.647
  • Water Solubility: Soluble to 100 mM in DMSO
  • Safety Statements: R22
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 585.6 °C at 760 mmHg
  • Molecular Weight: 327.33128
  • InchiKey: NZHGWWWHIYHZNX-CSKARUKUSA-N
  • InChI: InChI=1S/C18H17NO5/c1-23-15-9-7-12(11-16(15)24-2)8-10-17(20)19-14-6-4-3-
    5-13(14)18(21)22/h3-11H,1-2H3,(H,19,20)(H,21,22)/b10-8+
  • Risk Statements: S26;S36
  • Molecular Formula: C18H17NO5
  • Molecular Structure:CAS No:53902-12-8 2-[[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino]benzoic acid
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53902-12-8 Tranilast

  • Creative Enzymes uses its expertise in enzyme manufacturing to supply customers enzymes using for life science research and production of medicines, food, alcohol, beer, fruit juice, fabric, paper, leather goods, etc. We provide Tranilast More inform...
  • Min. Order: 10
  • United States Creative Enzymes [Manufacturer]
  • Tel: 1-516-6698109
  • Fax: 1-631-9388127
  • Address: 45-1 Ramsey Road, Shirley New York,New YorkUnited States
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53902-12-8 53902-12-8 & Tranilast

  • Product Name: Tranilast Certification:ISO9001 CAS: 53902-12-8 MF: C18H17NO5 MW: 327.33 Assay: 99% Standard: enterprise Standard Packaging : 25kg/drum or according to customer's requirement Payment Terms:L/C or T/T ,Bank Transfer and WU. Delivery Time...
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  • FOB Price: USDfalse - false /
  • China Wuhan Hezhong Bio-Chemical Manufacture Co., Ltd [Manufacturer, Trading Company]
  • Tel: 86-027-50755950
  • Fax: 86-027-88048077
  • Address: No. 496, Zhongshan Road, Wuchang District, Wuhan 430064, China. Wuhan,HebeiChina
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53902-12-8 Tranilast

  • Product Name: Tranilast Synonyms: 2-[[3-(3,4-DIMETHOXYPHENYL)-1-OXO-2-PROPENYL]AMINO] BENZOIC ACID;TRANILAST;2-((3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl)amino)-benzoicaci;n-(3,4-dimethoxycinnamoyl)-anthranilicaci;n-5’;rizaben;SB-252218;N-(3',4'-DIM...
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  • China Wuhan Senwayer Century Chemical Co.,Ltd [Manufacturer]
  • Tel: 86-027-59707018
  • Address: 20#Xudong Street,Wuhan China Wuhan,HubeiChina
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53902-12-8 tranilast

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53902-12-8 tranilast

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi ,ShanXiChina
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53902-12-8 tranilast

  • China XinChem Corporation [Manufacturers]
  • Tel: +86-(21)-34123252
  • Fax: +86-(21)-54153973
  • Address: 102/30, 3455 Chunshen Road, Shanghai 201100, ,ShanghaiChina
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53902-12-8 tranilast

  • China Shanghai Xunxin Chemical Co., Ltd [Manufacturers]
  • Tel: +86-(21)-38218795
  • Fax: +86-(21)-38218795
  • Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315, Shanghai,ShanghaiChina
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53902-12-8 TRANILAST

  • Germany BIOTREND Chemikalien GmbH [Manufacturer]
  • Tel: ++49 (0)2 21 9 49 83 20
  • Fax: ++49 (0)2 21 9 49 83 25
  • Address: BIOTREND Chemikalien GmbH
    Eupener Str. 157
    D - 50933 Cologne
    Germany ,Germany
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53902-12-8 Tranilast

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53902-12-8 TRANILAST

  • Germany Cfm Oskar Tropitzsch [Manufacturer]
  • Tel: +49-9231-9619-0
  • Fax: +49-9231-9619-60
  • Address: Cfm Oskar Tropitzsch
    Waldershofer Str. 49-51
    95615 Marktredwitz
    Germany ,Germany
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References of 2-[[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino]benzoic acid
Title: Tranilast
CAS Registry Number: 53902-12-8
CAS Name: 2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propenyl]amino]benzoic acid
Synonyms: N-(3¢,4¢-dimethoxycinnamoyl)anthranilic acid
Manufacturers' Codes: N-5¢
Trademarks: Rizaben (Kissei)
Molecular Formula: C18H17NO5
Molecular Weight: 327.33
Percent Composition: C 66.05%, H 5.23%, N 4.28%, O 24.44%
Literature References: Orally active anti-allergic agent. Prepn: K. Harita et al., DE 2402398; idem, US 3940422 (1974, 1976 both to Kissei). Pharmacological properties: H. Azuma et al., Br. J. Pharmacol. 58, 483 (1976). Mechanism of action study: Y. Iijima et al., Biochem. Biophys. Res. Commun. 93, 912 (1980). Clinical study in pediatric bronchial asthma: H. Shioda, Allergy 34, 213 (1979). Toxicity studies: M. Nakazawa et al., Oyo Yakuri 12, 385, 407 (1976), C.A. 88, 115327-8 (1978). Series of articles on teratogenicity tests: Iyakuhin Kenkyu 9, 148-193 (1978), C.A. 88, 130930f, 146300m-303q (1978).
Properties: Crystals from chloroform, mp 211-213°. LD50 in male, female mice, male, female rats (mg/kg): 780, 680, 1600, 1100 orally; 410, 385, 405, 395 i.p.; 2630, 2820, 3630, 3060 s.c. (Nakazawa, p 385).
Melting point: mp 211-213°
Toxicity data: LD50 in male, female mice, male, female rats (mg/kg): 780, 680, 1600, 1100 orally; 410, 385, 405, 395 i.p.; 2630, 2820, 3630, 3060 s.c. (Nakazawa, p 385)
Therap-Cat: Antiallergic.
Keywords: Antiallergic.