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CAS No 54-85-3 , pyridine-4-carbohydrazide

  • Name: pyridine-4-carbohydrazide
  • Synonyms: Nicizina; Cotinazin; Neoteben; Isonicotinohydrazide; Nydrazid;Isonicotinic acid hydrazide;pyridine-4-carbohydrazide; Andrazide; Dinacrin; Rimifon;
  • CAS Registry Number:
  • Transport: HAZARD
  • Melting Point: 170-174 ºC
  • Flash Point: °Cat760mmHg
  • Boiling Point: °Cat760mmHg
  • Density: 1.244g/cm3
  • Refractive index: 1.5502 (18 C)
  • Water Solubility: 14 G/100 ML (25 ºC)
  • Safety Statements: R22;R36/37/38;R40
  • Hazard Symbols: Xn: Harmful;
  • HS Code: 29333999
  • Flash Point: °Cat760mmHg
  • EINECS: 200-214-6
  • Molecular Weight: 137.13928
  • InchiKey: QRXWMOHMRWLFEY-UHFFFAOYSA-N
  • InChI: InChI=1S/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10)
  • Risk Statements: S26;S36/37/39
  • Molecular Formula: C6H7N3O
  • Molecular Structure:CAS No:54-85-3 pyridine-4-carbohydrazide
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54-85-3 Isoniazid

  • Isoniazid English Synonyms: 4-PYRIDINECARBOHYDRAZIDE;4-PYRIDINECARBOXYLIC ACID HYDRAZIDE;AKOS BBS-00004103;HYCOZID;LABOTEST-BB LT00146690;INAH;ISONICOTINIC ACID HYDRAZIDE;ISONIAZIDE CAS NO.: 54-85-3 Assay: 98% Molecular Formula:C6H7N3O Molecular Weig...
  • Min. Order: 100
  • FOB Price: USDfalse - true /
  • China Hubei Yuancheng Chemical Co.,Ltd [Manufacturer]
  • Tel: 86-27-68886667
  • Fax: 86-27-88048077
  • Address: NO866, Ziyang Road Wuhan,HubeiChina
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54-85-3 Isonicotinic acid hydrazide

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54-85-3 Isonicotinic acid hydrazide

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi ,ShanXiChina
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54-85-3 Isonicotinic acid hydrazide

  • China Watson International Ltd. []
  • Tel: +86-(512)-55117610
  • Fax: +86-(512)-55117630
  • Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332, ,China
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54-85-3 Isonicotinic acid hydrazide

  • United States HBCChem, Inc. [Manufacturers]
  • Tel: +1-510-219-6317
  • Fax: +1-510-675-0318
  • Address: Union City,CaliforniaUnited States
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54-85-3 Isonicotinic acid hydrazide

  • China YiPeng Chemical [Manufacturers]
  • Tel: 571 85376369
  • Fax: 571 88233092
  • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China ,ZheJiangChina
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54-85-3 Isonicotinyl Hydrazide (INH)

  • China Ningbo Inno Pharmchem Co., Ltd. [Manufacturers]
  • Tel: +86-(574)-87319282
  • Fax: +86-(574)-56877908
  • Address: 5F, Building 4, 1035 Guangxian Rd., Ningbo Hi-Tech Park, Ningbo, Zhejiang 315040, Ningbo,ZhejiangChina
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54-85-3 Isoniazid

  • Isoniazid MF: C6H7N3O MW: 137.14 CAS: 54-85-3 Spec: Apperance: white to off white Crystal powder Package:25kg/drum
  • Min. Order: 1
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  • China China Skyrun Industrial CO.,Ltd [Manufacturer]
  • Tel: 86-576-84768865
  • Address: Chemical Development Zone nanjing,JiangsuChina
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54-85-3 Isoniazid (Rimifon)

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54-85-3 ISO-NICOTINIC ACID HYDRAZIDE

  • United States Aceto Corp. [Manufacturer]
  • Tel: 516-627-6000
  • Fax: 516-627-6093
  • Address: One Hollow Lane
    Lake Success, NY 11042-1215 ,United States
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References of pyridine-4-carbohydrazide
Title: Isoniazid
CAS Registry Number: 54-85-3
CAS Name: 4-Pyridinecarboxylic acid hydrazide
Synonyms: isonicotinic acid hydrazide; isonicotinoylhydrazine; isonicotinylhydrazine; INH; rimitsid; tubazid
Manufacturers' Codes: RP-5015; FSR-3
Trademarks: Isonex (Pfizer); Isotamine (Valeant); Isozid (Fatol); Neoteben (Bayer); Nicizina (Pharmacia); Nicozid (Piam); Nydrazid (BMS); Rimifon (Pharmion); tebesium (Pharma Wernigerode); Tibinide (Recip); Valifol (Valdecasas)
Molecular Formula: C6H7N3O
Molecular Weight: 137.14
Percent Composition: C 52.55%, H 5.14%, N 30.64%, O 11.67%
Literature References: Prepn: Meyer, Mally, Monatsh. Chem. 33, 400 (1912); Lock, Pharm. Ind. 14, 366 (1952); Urbanski et al., Rocz. Chem. 27, 161 (1953); Gasson, US 2830994 (1958 to Distillers). Compositions for combating tuberculosis: H. H. Fox, US 2596069 (1952 to Hoffmann-La Roche). Pharmacokinetics: W. W. Weber, D. W. Hein, Clin. Pharmacokinet. 4, 401 (1979). Mechanism of action study: K. Johnsson et al., J. Am. Chem. Soc. 117, 5009 (1995). Toxicity data: E. H. Jenney, C. C. Pfeiffer, J. Pharmacol. Exp. Ther. 122, 110 (1958). Evaluation of carcinogenic risk: IARC Monographs 4, 159 (1974). Comprehensive description: G. A. Brewer, Anal. Profiles Drug Subs. 6, 183-258 (1977). Clinical trial in HIV-positive patients: J. W. Pape et al., Lancet 342, 268 (1993). Review of use in prevention and treatment of TB: American Thoracic Society, Am. Rev. Respir. Dis. 134, 355-363 (1986); T. J. Jordan et al., ibid. 144, 1357-1360 (1991).
Properties: Crystals from alc, mp 171.4°. uv max (water): 266 nm (E1%1cm 378); (0.01N HCl): 265 nm (E1%1cm ~420). Soly in water at 25°: about 14%; at 40°: about 26%; in alc at 25°: about 2%, in boiling alc: about 10%; in chloroform: about 0.1%. Practically insol in ether, benzene. pH of a 1% aq soln 5.5 to 6.5. Aqueous solns may be sterilized at 120° for 30 min. LD50 in mice (mg/kg): 151 i.p., 149 i.v. (Jenney, Pfeiffer).
Melting point: mp 171.4°
Absorption maximum: uv max (water): 266 nm (E1%1cm 378); (0.01N HCl): 265 nm (E1%1cm ~420)
Toxicity data: LD50 in mice (mg/kg): 151 i.p., 149 i.v. (Jenney, Pfeiffer)
 
Derivative Type: 4-Aminosalicylate
CAS Registry Number: 2066-89-9
Synonyms: Pasiniazide
Manufacturers' Codes: GEWO-399
Molecular Formula: C13H14N4O4
Molecular Weight: 290.27
Percent Composition: C 53.79%, H 4.86%, N 19.30%, O 22.05%
Literature References: An equimolecular salt produced by dissolving the components in hot dil alc, followed by cooling and evapn: Charonnat, Boime, Compt. Rend. 236, 2140 (1953). Prepn: CH 303085 (1955 to Hoffmann-La Roche).
Properties: Yellow crystals from methanol or ethanol, mp 142-144°. Sparingly sol in water. uv max 272, 303 nm (E1%1cm 550, 445).
Melting point: mp 142-144°
Absorption maximum: uv max 272, 303 nm (E1%1cm 550, 445)
 
Derivative Type: Methanesulfonate
CAS Registry Number: 13447-95-5
CAS Name: 4-Pyridinecarboxylic acid 2-(sulfomethyl)hydrazide
Synonyms: methaniazide
Molecular Formula: C7H9N3O4S
Molecular Weight: 231.23
Percent Composition: C 36.36%, H 3.92%, N 18.17%, O 27.68%, S 13.87%
Literature References: Prepn: Logemann, US 2759944 (1956 to Carlo Erba).
Properties: Crystals, dec 187-189°.
 
Derivative Type: Methanesulfonate sodium
CAS Registry Number: 3804-89-5
Synonyms: Sodium isonicotinylhydrazide methanesulfonate
Molecular Formula: C7H8N3NaO4S
Molecular Weight: 253.21
Percent Composition: C 33.20%, H 3.18%, N 16.59%, Na 9.08%, O 25.27%, S 12.66%
Properties: Yellow crystals from water, dec 164-167°.
 
Therap-Cat: Antibacterial (tuberculostatic).
Therap-Cat-Vet: Antibacterial (tuberculostatic); anti-actinomycotic agent.
Keywords: Antibacterial (Tuberculostatic).