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CAS No 541-15-1 , (3R)-3-hydroxy-4-(trimethylazaniumyl)butanoate

  • Name: (3R)-3-hydroxy-4-(trimethylazaniumyl)butanoate
  • Synonyms: (R)-Carnitine; 541-15-1; (-)-Carnitine; vitamin BT;(3R)-3-hydroxy-4-(trimethylazaniumyl)butanoate; (-)-L-Carnitine; Carnitine; Carnitor; Levocarnitine; Karnitin;L-carnitine;
  • CAS Registry Number:
  • Transport: 25kgs
  • Melting Point: 208-212 ºC
  • Density: 99%
  • Refractive index: -32 ° (C=1, H2O)
  • Alpha: -31 º (C=10, H2O)
  • Water Solubility: 2500 G/L (20 ºC)
  • Safety Statements: R36/37/38
  • Hazard Symbols: Xi: Irritant;
  • EINECS: 208-768-0
  • Molecular Weight: 161.1989
  • InchiKey: PHIQHXFUZVPYII-ZCFIWIBFSA-N
  • InChI: InChI=1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1
  • Risk Statements: S26;S37/39
  • Molecular Formula: C7H15NO3
  • Molecular Structure:CAS No:541-15-1 (3R)-3-hydroxy-4-(trimethylazaniumyl)butanoate
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541-15-1 L-carnitine

  • L-carnitineL-carnitine, 98%
  • China PMIDA AGROCHEMICAL CO.,LTD [Manufacturer]
  • Tel: +86-023-67030808-8010
  • Fax: +86-023-67030809
  • Address: 17F,Venus Science Incubate Center,No.60 Xingguang Road,New North Zone401121 ChongqingCHINA Chongqing,nullChina
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541-15-1 L-Carnitine

  • L-Carnitine, 98%
  • China Shanghai Rainbow Chemistry Co., Ltd. [Manufacturer]
  • Tel: +86-21-64968086
  • Fax: +86-21-64968086
  • Address: Room 128, Building B, No. 8 Lane 1305, Huajing Road, Xuhui District, Shanghai, P.R. China 200000 Shanghai CHINA Shanghai,nullChina
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541-15-1 L-Carnitine, 99+%

  • L-Carnitine, 99+%
  • Belgium Alkemi [Manufacturer]
  • Tel: +32 9 340 49 49
  • Fax: +32 9 340 49 47
  • Address: Poststraat, 82 B-9160 Lokeren Belgium null,nullBelgium
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541-15-1 L(-)-Carnitine

  • China XinChem Corporation [Manufacturers]
  • Tel: +86-(21)-34123252
  • Fax: +86-(21)-54153973
  • Address: 102/30, 3455 Chunshen Road, Shanghai 201100, null,ShanghaiChina
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541-15-1 L(-)-Carnitine

  • China Fast Pharm Co.,Ltd [Manufacturers]
  • Tel: 8602133538380
  • Fax: 86-021-32082820
  • Address: No.17#-6D. 830 Lane,Maotai Road Shanghai,SH200336,China Shanghai,ShanghaiChina
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541-15-1 L(-)-Carnitine

  • L(-)-Carnitine
  • China Betapharma Shanghai Inc.Co., Ltd [Manufacturer]
  • Tel: 86-21-62951620
  • Fax: 86-21-32230794
  • Address: Jinming Building 12A No. 8 Zunyi(S) Rd. Shanghai China 200336 shanghaiCHINA shanghai,nullChina
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541-15-1 L-Carnitine

  • L-Carnitine, 99.00%min
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,nullChina
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541-15-1 L(-)-Carnitine

  • China Shanghai Hanhong Chemical Co., Ltd. [Manufacturer, Trading Company, Agent]
  • Tel: +86-(21)-64762736, 64531573
  • Fax: +86-(21)-54291107
  • Address: 206-209, NO.1 Building , NO.245,Jiachuan Road, Xuhui District, Shanghai, Xuhui District,ShanghaiChina
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541-15-1 L-CARNITINE

  • L-CARNITINE, 98-102% EP
  • United States INTERNATIONAL LABORATORY LIMITED [Manufacturer]
  • Tel: ( 650 ) 278-9963
  • Fax: ( 650 ) 589-2786
  • Address: 1067 SNEATH LN SAN BRUNO CA 94066, USA SAN BRUNOUNITED STATES SAN BRUNO,nullUnited States
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541-15-1 L-Carnitine

  • L-Carnitine
  • China Shanghai Synnad Chemical Co., Ltd. [Importer/Exporter]
  • Tel: 86 21 5109 7911
  • Fax: 86 21 5109 7955
  • Address: B-5 Ecust Science Park, No. 18, Lane 1305, Hua Jing Road, Shanghai 200231 China Shanghai,ShanghaiChina
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References of (3R)-3-hydroxy-4-(trimethylazaniumyl)butanoate
Title: Carnitine
CAS Registry Number: 541-15-1
CAS Name: (2R)-3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium inner salt
Synonyms: L-(3-carboxy-2-hydroxypropyl)trimethylammonium hydroxide inner salt; (-)-b-hydroxy-g-trimethylaminobutyric acid; L-carnitine; levocarnitine; vitamin BT
Trademarks: Cardiogen (UCB); Carnicor (Sigma-Tau); Carnitor (Sigma-Tau); L-Carn (Sigma-Tau); Lefcar (GSK); Levocarnil (Sigma-Tau); Miocor (Ecobi); Miotonal (Caber); Nefrocarnit (Medice)
Molecular Formula: C7H15NO3
Molecular Weight: 161.20
Percent Composition: C 52.16%, H 9.38%, N 8.69%, O 29.78%
Literature References: Essential cofactor of fatty acid metabolism; required for the transport of fatty acids through the inner mitochondrial membrane. Synthesized primarily in the liver and kidney; highest concentrations found in heart and skeletal muscle. Named derived from the Latin word, carnis, meaning meat or flesh. Dietary sources include red meat, dairy products, beans, avocado. Isoln from meat extract: W. Gulewitsch, R. Krimberg, Z. Physiol. Chem. 45, 326 (1905); H. E. Carter, P. K. Bhattacharyya, Methods Enzymol. III, 660 (1957). Identification as vitamin BT: H. E. Carter et al., Arch. Biochem. Biophys. 38, 405 (1952). Synthesis: M. Tomita, Y. Sendju, Z. Physiol. Chem. 169, 263 (1927); R. Voeffray et al., Helv. Chim. Acta 70, 2058 (1987). Enantioselective synthesis from glycerol: M. Marzi et al., J. Org. Chem. 65, 6766 (2000). Biosynthesis: G. Wolf, C. R. A. Berger, Arch. Biochem. Biophys. 92, 360 (1961). Absolute configuration: T. Kaneko, R. Yoshida, Bull. Chem. Soc. Jpn. 35, 1153 (1962). Metabolism in humans: M. E. Mitchell, Am. J. Clin. Nutr. 31, 293 (1978). Historical review: G. Fraenkel, S. Friedman, Vitam. Horm. XV, 73-118 (1957). Review of physiological significance and deficiency syndromes: C. J. Rebouche, D. J. Paulson, Annu. Rev. Nutr. 6, 41-66 (1986); of clinical pharmacology: J. J. Bahl, R. Bressler, Annu. Rev. Pharmacol. Toxicol. 27, 257-277 (1987); of biosynthesis in mammals: F. M. Vaz, R. J. A. Wanders, Biochem. J. 361, 417-429 (2002). Review of effect on myocardial metabolism and clinical experience in ischemic heart disease: R. Lango et al., Cardiovasc. Res. 51, 21-29 (2001); of use as dietary supplement in athletes: H. Karlic, A. Lohninger, Nutrition 20, 709-715 (2004). Symposium on physiology, pharmacology and therapeutic potential: Ann. N.Y. Acad. Sci. 1033, 1-197 (2004).
Properties: Crystals from anhydrous ethanol + acetone, dec 196-198° (Carter, Bhattacharyya); also reported as crystals from isopropanol, mp 200° (dec) (Marzi). Very hygroscopic solid. [a]D25 -31.3° (c = 10 in water); [a]54625 -37.0° (c = 10 in water). Sol in water, hot alcohol. Practically insol in acetone, ether, benzene.
Melting point: mp 200° (dec) (Marzi)
Optical Rotation: [a]D25 -31.3° (c = 10 in water); [a]54625 -37.0° (c = 10 in water)
 
Derivative Type: Hydrochloride
CAS Registry Number: 6645-46-1
Synonyms: Levocarnitine chloride
Trademarks: Flatistine (Sanofi-Aventis)
Molecular Formula: C7H15NO3.HCl
Molecular Weight: 197.66
Percent Composition: C 42.54%, H 8.16%, N 7.09%, O 24.28%, Cl 17.94%
Properties: Crystals, dec 142°.
 
Derivative Type: DL-Form
CAS Registry Number: 406-76-8
Synonyms: g-Amino-b-hydroxybutyric acid trimethylbetaine; g-trimethyl-b-hydroxybutyrobetaine
Literature References: Synthesis: E. Strack et al., Ber. 86, 525 (1953); H. E. Carter, P. K. Bhattacharyya, J. Am. Chem. Soc. 75, 2503 (1953).
Properties: Hygroscopic crystalline solid, dec 195-197°. Sol in water, ethanol.
 
Derivative Type: DL-Form hydrochloride
CAS Registry Number: 461-05-2
Properties: Needles from ethanol, mp 196° (dec). Very sol in water; sol in hot ethanol; slightly sol in cold ethanol. Practically insol in acetone, ether.
Melting point: mp 196° (dec)
 
Derivative Type: D-Form
CAS Registry Number: 541-14-0
Literature References: Prepn: S. Friedman et al., Arch. Biochem. Biophys. 66, 10 (1957).
Properties: Crystals, dec 210-212°. [a]D +30.9°. Very sol in water and alcohol. Practically insol in acetone and ether.
Optical Rotation: [a]D +30.9°
 
Derivative Type: D-Form hydrochloride
CAS Registry Number: 10017-44-4
Properties: Crystals, dec 142°.
 
Therap-Cat: Vitamin (enzyme cofactor).
Keywords: Enzyme Cofactor; Vitamin/Vitamin Source.