Home > Name List By 2 > 2-(1,3-dimethyl-2,6-dioxopurin-7-yl)ethyl 2-(4-chlorophenoxy)-2-methylpropanoate

CAS No 54504-70-0 , 2-(1,3-dimethyl-2,6-dioxopurin-7-yl)ethyl
2-(4-chlorophenoxy)-2-methylpropanoate

  • Name: 2-(1,3-dimethyl-2,6-dioxopurin-7-yl)ethyl
    2-(4-chlorophenoxy)-2-methylpropanoate
  • Synonyms: Duolip; MLS003115174;2-(1,3-dimethyl-2,6-dioxopurin-7-yl)ethyl
    2-(4-chlorophenoxy)-2-methylpropanoate;Etofylline clofibrate; Etofyllini clofibras [INN-Latin]; ML 1024; THEOFIBRATE; 54504-70-0; Etofyllinclofibrat [German];
  • CAS Registry Number:
  • Flash Point: 326.2°C
  • Boiling Point: 615.8°C at 760 mmHg
  • Density: 1.37g/cm3
  • Refractive index: 1.617
  • Safety Statements: Moderately toxic by ingestion and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of Cl and NOx. See also ESTERS.
  • Flash Point: 326.2°C
  • EINECS: 259-191-6
  • Molecular Weight: 420.84684
  • InchiKey: KYAKGJDISSNVPZ-UHFFFAOYSA-N
  • InChI: InChI=1S/C19H21ClN4O5/c1-19(2,
    29-13-7-5-12(20)6-8-13)17(26)28-10-9-24-11-21-15-14(24)16(25)23(4)18(27)
    22(15)3/h5-8,11H,9-10H2,1-4H3
  • Molecular Formula: C19H21ClN4O5
  • Molecular Structure:CAS No:54504-70-0 2-(1,3-dimethyl-2,6-dioxopurin-7-yl)ethyl<br />2-(4-chlorophenoxy)-2-methylpropanoate
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54504-70-0 ETOFYLLINE CLOFIBRATE

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong ,Hong kong
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54504-70-0 Propanoic acid,2-(4-chlorophenoxy)-2-methyl-,2-(1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purin-7-yl)ethyl ester

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54504-70-0 Etofylline clofibrate

  • Etofylline clofibrate, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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54504-70-0 Etofylline Clofibrate

  • Etofylline Clofibrate, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,China
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54504-70-0 Etofylline Clofibrate

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54504-70-0 ETOFYLLINE CLOFIBRATE

  • India JAI RADHE SALES []
  • Fax: 0091-79-26569884
  • Address: 309/310 HARIKRUPA TOWER,NR.OLD SHARDA MANDIR CHAR RASTA,ELLISBRIDGE ,AHMEDABAD,GUJRAT , INDIA. ,India
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54504-70-0 Etofylline Clofibrate

  • India Shreeji Pharma International [Manufacturers]
  • Tel: +91-265-3019110
  • Fax: +91-265-2465036
  • Address: FF/10, Narsinghdham Complex, Sangam Chararasta, Harni Road, Vadodara, Gujarat 390018, Vadodara,GujaratIndia
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54504-70-0 Etofylline Clofibrate

  • China Facus Pharmaceutical Co., Ltd. [Manufacturers]
  • Tel: +86-(574)-6237-8411
  • Fax: +86-(574)-6237-8410
  • Address: 24Fl, Yuanjing Building, Beilun, Ningbo, Zhejiang 315800, Ningbo,ZhejiangChina
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54504-70-0 ETOFYLLINE CLOFIBRATE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China ,China
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References of 2-(1,3-dimethyl-2,6-dioxopurin-7-yl)ethyl
2-(4-chlorophenoxy)-2-methylpropanoate
Title: Theofibrate
CAS Registry Number: 54504-70-0
CAS Name: 2-(4-Chlorophenoxy)-2-methylpropanoic acid 2-(1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purin-7-yl)ethyl ester
Synonyms: 2-(p-chlorophenoxy)-2-methylpropionic acid ester with 7-(2-hydroxyethyl)theophylline; 1-(theophyllin-7-yl)ethyl 2-(p-chlorophenoxy)isobutyrate; etofylline clofibrate
Manufacturers' Codes: ML-1024
Trademarks: Duolip (Merckle)
Molecular Formula: C19H21ClN4O5
Molecular Weight: 420.85
Percent Composition: C 54.22%, H 5.03%, Cl 8.42%, N 13.31%, O 19.01%
Literature References: Deriv of clofibric acid, q.v., with antilipemic, antithrombotic, and platelet-aggregation inhibitory activity: Prepn: G. Metz, M. Specker, DE 2308826; eidem, US 3984413 (1974, 1976 both to Merckle); eidem, Arzneim.-Forsch. 25, 1686 (1975). Hypolipemic activity: G. Metz et al., ibid. 27, 1173 (1977). Series of articles on chemistry, biopharmaceutic evaluation, pharmacology, toxicology, clinical studies: ibid. 30, 2013-2074 (1980).
Properties: Colorless crystals from ethanol, mp 133-135°. Practically insol in water at pH 2-7.4 and in cold alcohols. Sol in acetone, chloroform, hot alcohols. LD50 in mice, rats, dogs (g/kg): 11.7, 17.0, >10.0 orally (Metz et al.).
Melting point: mp 133-135°
Toxicity data: LD50 in mice, rats, dogs (g/kg): 11.7, 17.0, >10.0 orally (Metz et al.)
Therap-Cat: Antilipemic.
Keywords: Antilipemic; Fibrates.