Home > Name List By other > (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4, 6,8-tetraenoic acid China

CAS No 55079-83-9 , (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,
6,8-tetraenoic acid Search by region : China

  • Name: (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,
    6,8-tetraenoic acid
  • Synonyms: Acitretina; Neotigason;(2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,
    6,8-tetraenoic acid; 55079-83-9; Acitretinum; Acitretine; Etretin; Retinoid etretin; all-trans-Acitretin;Soriatane;
  • CAS Registry Number:
  • Transport: UN 3077
  • Density: 1.051 g/cm3
  • Refractive index: 1.569
  • Safety Statements: R36/38,R61,R50/53,
  • Hazard Symbols: T:Toxic;N:Dangerousfortheenvironment;
  • EINECS: 259-474-4
  • Molecular Weight: 326.42934
  • InchiKey: IHUNBGSDBOWDMA-AQFIFDHZSA-N
  • InChI: InChI=1S/C21H26O3/c1-14(8-7-9-15(2)12-21(22)23)10-11-19-16(3)13-20(24-6)
    18(5)17(19)4/h7-13H,1-6H3,(H,22,23)/b9-7+,11-10+,14-8+,15-12+
  • Risk Statements: S53,S37/39,S45,S60,S61,
  • Molecular Formula: C21H26O3
  • Molecular Structure:CAS No:55079-83-9 (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,<br />6,8-tetraenoic acid

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55079-83-9 Acitretin

  • China Chemrio International Limited [Manufacturer]
  • Tel: +86 574 2789 1268/ +86-139 5789 5864 (mobile)
  • Fax: +86 574 2789 1266
  • Address: Chemrio International Limited
    Room 611-612, Wante Business Center
    No.487 Yangmuqi Road,
    Hi-tech Park Ningbo, 315040,China null,nullChina
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55079-83-9 Etretin

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55079-83-9 Acitretin

  • Acitretin
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,nullChina
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55079-83-9 Acitretin

  • AcitretinAcitretin, 98%
  • China PMIDA AGROCHEMICAL CO.,LTD [Manufacturer]
  • Tel: +86-023-67030808-8010
  • Fax: +86-023-67030809
  • Address: 17F,Venus Science Incubate Center,No.60 Xingguang Road,New North Zone401121 ChongqingCHINA Chongqing,nullChina
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55079-83-9 Acitretin

  • Acitretin, 98%
  • China Shanghai Rainbow Chemistry Co., Ltd. [Manufacturer]
  • Tel: +86-21-64968086
  • Fax: +86-21-64968086
  • Address: Room 128, Building B, No. 8 Lane 1305, Huajing Road, Xuhui District, Shanghai, P.R. China 200000 Shanghai CHINA Shanghai,nullChina
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55079-83-9 Etretin

  • China XinChem Corporation [Manufacturers]
  • Tel: +86-(21)-34123252
  • Fax: +86-(21)-54153973
  • Address: 102/30, 3455 Chunshen Road, Shanghai 201100, null,ShanghaiChina
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55079-83-9 Acetretin

  • Acetretin, EP4
  • China Suzhou Rovathin Foreign Trade Co.,Ltd [Manufacturer]
  • Tel: 86-512-65816829/ 86-512-61978430
  • Fax: 86-512-65816839
  • Address: Suzhou Rovathin Foreign Trade Co.,Ltd
    (Sales Company of Affiliated Plant in China)
    Room 603, 327 of ShiZi Street,
    Suzhou, Jiangsu, China 215006 null,nullChina
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55079-83-9 Tigason

  • Tigason
  • China Betapharma Shanghai Inc.Co., Ltd [Manufacturer]
  • Tel: 86-21-62951620
  • Fax: 86-21-32230794
  • Address: Jinming Building 12A No. 8 Zunyi(S) Rd. Shanghai China 200336 shanghaiCHINA shanghai,nullChina
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55079-83-9 Acitretin

  • Acitretin, 98.50%Min
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,nullChina
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55079-83-9 Acitretin

  • China Trust&We Co., Ltd. [Manufacturer]
  • Tel: +86-21-61044582
  • Fax: +86-21-61044583
  • Address: 1-102,No.11,Dongjiaominxiang Alley,
    Dongcheng District,
    Beijing 100005,China null,nullChina
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References of (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,
6,8-tetraenoic acid
Title: Acitretin
CAS Registry Number: 55079-83-9
CAS Name: (2E,4E,6E,8E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid
Synonyms: etretin
Manufacturers' Codes: Ro-10-1670
Trademarks: Neotigason (Roche); Soriatane (Roche)
Molecular Formula: C21H26O3
Molecular Weight: 326.43
Percent Composition: C 77.27%, H 8.03%, O 14.70%
Literature References: Synthetic retinoid; free acid form and major metabolite of etretinate, q.v. Prepn: W. Bollag et al., DE 2414619; eidem, US 4105681 (1974, 1978 both to Hoffmann-La Roche). Teratogenicity study: A. Kistler, H. Hummler, Arch. Toxicol. 58, 50 (1985). HPLC determn in plasma: N. R. Al-Mallah et al., Anal. Lett. 21, 1603 (1988). Pharmacokinetics in humans: F. G. Larsen et al., Pharmacol. Toxicol. 62, 159 (1988). Clinical evaluation in cutaneous lupus erythematosus: T. Ruzicka et al., Arch. Dermatol. 124, 897 (1988). Review of clinical pharmacology: A. Vahlquist, O. Rollman, Dermatologica 175, Suppl. 1, 20-27 (1987). Review of clinical studies in psoriatic and nonpsoriatic dermatoses: J.-M. Geiger, B. M. Czarnetzki, ibid. 176, 182-190 (1988).
Properties: Crystals from hexane, mp 228-230°. LD50 i.p. in mice (mg/kg): >4000 (1 day), 700 (10 days), 700 (20 days) (Bollag, 1978).
Melting point: mp 228-230°
Toxicity data: LD50 i.p. in mice (mg/kg): >4000 (1 day), 700 (10 days), 700 (20 days) (Bollag, 1978)
Therap-Cat: Antipsoriatic.
Keywords: Antipsoriatic.