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CAS No 551-11-1 , Prostaglandin F2a Search by region : China

  • Name: Prostaglandin F2a
  • Synonyms: Prostaglandin F2a; Prostaglandin F2-alpha; 9,11,15-trihydroxyprosta-5,13-dien-1-oicacid ; cyclosin ; enzaprost ;Dinoprost;prostaglandin F2-alpha; enzaprostf ; glandin; dinolytic ; amoglandin ; Prostaglandin F2A; (5Z,9a,11a,13E,15S)-9,11,15-Trihydroxyprosta-5,13-diene-1-oic acid;
  • CAS Registry Number:
  • Density: 1.153 g/cm3
  • Refractive index: 1.569
  • Safety Statements: Poison by subcutaneous, intravenous, and intramuscular routes. Moderately toxic by ingestion. Human and experimental teratogenic and experimental reproductive effects. Human reproductive effects by subcutaneous, intravenous, intramuscular, intraperitoneal, intravaginal, and intraplacental routes: postpartum depression and other maternal effects, abortion, and changes in measures of fertility. Human teratogenic effects by intraplacental route: extra embryonic structures. Human systemic effects by intravenous route: hypermotility, diarrhea, nausea or vomiting. Human mutation data reported. When heated to decomposition it emits acrid smoke and fumes.
  • Molecular Weight: 354.48
  • InChI: InChI=1/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1
  • Molecular Formula: C20H34O5
  • Molecular Structure:CAS No:551-11-1 Prostaglandin F2a

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551-11-1 Dinoprost

  • Dinoprost
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,nullChina
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551-11-1 Promolate

  • Promolate, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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551-11-1 Dinprost

  • Dinprost, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
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551-11-1 dinoprost

  • China Boronsyn Co.,Ltd [Manufacturer]
  • Tel: +86-21-58407925
  • Fax: +86-21-58408291
  • Address: 1213 JunMin Road,Pudong,China null,nullChina
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551-11-1 Dinoprost

  • China Watson International Ltd. null
  • Tel: +86-(512)-55117610
  • Fax: +86-(512)-55117630
  • Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332, null,nullChina
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551-11-1 Dinprost, 99%

  • Dinprost, 99%
  • China Pleapharma Co.,Ltd [Manufacturer]
  • Tel: 86 23 67030808
  • Fax: 86 23 67030809
  • Address: 22F,Jingxin center,No.70 Xingguang Road,Yubei Zone,Chongqing402232 chongqingCHINA chongqing,nullChina
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551-11-1 Dinoprost

  • China Taizhou Crene Chempharm Co., Ltd. null
  • Tel: +86-(576)-88813233
  • Fax: +86-(576)-88670057
  • Address: Weiwu Load Economic Developed Zone, Taizhou, Zhejiang 318000, null,nullChina
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551-11-1 Dinoprost

  • China Huei-Ho International Co., Ltd. [Importer/Exporter]
  • Tel: +86-(21)-6273-7219, 6273-6279
  • Fax: +86-(21)-6129-4387, 62735948
  • Address: 20B,No.2,Lane 600,Peakway Tower,Tianshan Road, Shanghai, shanghai 200051, null,ShanghaiChina
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551-11-1 dinoprost

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551-11-1 DINOPROST TROMETAMOL

  • China Shanghai Yingxuan Chempharm Co., Ltd. [Manufacturer]
  • Tel: 86-21-50323911
  • Fax: 86-21-50323911
  • Address: Shanghai Yingxuan Chempharm Co., Ltd.
    No.1-303, 666 Taierzhuang Rd.,
    Pudong, Shanghai,
    CN-201206,China null,nullChina
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References of Prostaglandin F2a
Title: Prostaglandin F2a
CAS Registry Number: 551-11-1
CAS Name: (5Z,9a,11a,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic acid
Synonyms: 7-[3,5-dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl]-5-heptenoic acid; dinoprost; PGF2a
Manufacturers' Codes: U-14583
Trademarks: Enzaprost F (Ceva); Prostarmon F (Ono)
Molecular Formula: C20H34O5
Molecular Weight: 354.48
Percent Composition: C 67.77%, H 9.67%, O 22.57%
Literature References: One of the most biologically studied of the primary prostaglandins. Closely related to prostaglandin E2 (PGE2) in that both prostaglandins are biosynthesized from the same precursors and that PGF2a is the synthetic reduction product of PGE2. For refs to synthesis of dl and natural forms see Prostaglandin E2. Prepn of the tromethamine salt: W. Morozowich, DE 2126127; idem, US 3657327 (1971, 1972 both to Upjohn). Alternate synthesis of natural PGF2a: Schneider, Murray, J. Org. Chem. 38, 397 (1973); R. B. Woodward et al., J. Am. Chem. Soc. 95, 6853 (1973); G. Stork et al., ibid. 100, 8272 (1978); K. Kondo et al., Tetrahedron Lett. 1978, 3927; N. R. A. Beeley et al., Tetrahedron 37, Suppl. 9, 411 (1981); R. J. Cave et al., J. Chem. Soc. Perkin Trans. 1 1981, 646. Causes vasocontraction and exhibits luteolytic activity; is most commonly associated with its role in pregnancy: Karim et al., J. Obstet. Gynaecol. Brit. Commonw. 78, 172 (1971). Metabolism in female subjects: Granstrom, Samuelsson, J. Biol. Chem. 246, 5254 (1971). Toxicity data: T. Fujita et al., Iyakuhin Kenkyu 9, 261 (1978), C.A. 89, 71399k (1978). For general refs see Prostaglandins.
Properties: Natural form, crystals, mp 25-35°. [a]D25 +23.5° (c = 1 in tetrahydrofuran). Freely sol in methanol, abs ethanol, ethyl acetate, chloroform; slightly sol in water. Stable for two years in light resistant containers at 5-15°. Degrades in one week when exposed to sunlight or in three months at 40°. LD50 in rabbits (mg/kg): 2.5-5.0 i.v.; 2.5-5.0 i.m. (Fujita).
Melting point: mp 25-35°
Optical Rotation: [a]D25 +23.5° (c = 1 in tetrahydrofuran)
Toxicity data: LD50 in rabbits (mg/kg): 2.5-5.0 i.v.; 2.5-5.0 i.m. (Fujita)
 
Derivative Type: Tromethamine salt
CAS Registry Number: 38562-01-5
Trademarks: In-Synch (ProLabs); Lutalyse (Pharmacia & Upjohn)
Molecular Formula: C20H34O5.C4H11NO3
Molecular Weight: 475.62
Percent Composition: C 60.61%, H 9.54%, O 26.91%, N 2.94%
Properties: White or off-white cystalline powder, mp 100-101°. Readily sol in water to at least 200 mg/ml.
Melting point: mp 100-101°
 
Therap-Cat: Oxytocic; abortifacient.
Therap-Cat-Vet: Oxytocic.
Keywords: Abortifacient/Interceptive; Oxytocic; Prostaglandin/Prostaglandin Analog.