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CAS No 745-65-3 , Prostaglandin E1

  • Name: Prostaglandin E1
  • Synonyms: PGE1; 3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-cyclopentaneheptanoic acid;11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid;ALPROSTADIL;Prostaglandin E1; Prostaglandin E1 or AIPROSTADIL; Alprostadil (prostandin E1);
  • CAS Registry Number:
  • Transport: UN 2811
  • Melting Point: 115-116 ºC
  • Density: 1.131 g/cm3
  • Alpha: -64 º (C=1.0, C2H5OH)
  • Safety Statements: R22
  • Hazard Symbols: Xn: Harmful;
  • EINECS: 212-017-2
  • Molecular Weight: 354.48
  • InChI: InChI=1/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17?,19+/m0/s1
  • Risk Statements: S36
  • Molecular Formula: C20H34O5
  • Molecular Structure:CAS No:745-65-3 Prostaglandin E1
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745-65-3 Prostaglandin E1 (Alprostadil)

  • Product Name: Prostaglandin E1 (Alprostadil) Synonyms: 11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid; 3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-cyclopentaneheptanoic acid; PGE1 CAS: 745-65-3 MF: C20H34O5 MW: 354.48 EINECS: 212-017-2 Water Solubility: Ins...
  • China Biopro Chemicals Co., Ltd. [Manufacturer]
  • Tel: 86-21-30696096
  • Fax: 86-21-30697096
  • Address: Shenli Road 1183, Zhangjiang Hi-Tech Park Shanghai,ShanghaiChina
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745-65-3 Prostaglandin E1 (Alprostadil)

  • Product Name: Prostaglandin E1 (Alprostadil) Synonyms: 11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid; 3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-cyclopentaneheptanoic acid; PGE1 CAS: 745-65-3 MF: C20H34O5 MW: 354.48 EINECS: 212-017-2 Water Solubility: Ins...
  • China Biopro Chemicals Co,Ltd. [Manufacturer]
  • Tel: 86-21-30696096
  • Address: Shenli Road 1183, Zhangjiang Hi-Tech Park Shanghai,ShanghaiChina
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745-65-3 5alpha-androstant-3beta,17beta-diol

  • 5alpha-androstant-3beta,17beta-diol5alpha-androstant-3beta,17beta-diol, 98%
  • China PMIDA AGROCHEMICAL CO.,LTD [Manufacturer]
  • Tel: +86-023-67030808-8010
  • Fax: +86-023-67030809
  • Address: 17F,Venus Science Incubate Center,No.60 Xingguang Road,New North Zone401121 ChongqingCHINA Chongqing,China
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745-65-3 5alpha-Androstant-3beta,17beta-diol

  • 5alpha-Androstant-3beta,17beta-diol, 98%
  • China Shanghai Rainbow Chemistry Co., Ltd. [Manufacturer]
  • Tel: +86-21-64968086
  • Fax: +86-21-64968086
  • Address: Room 128, Building B, No. 8 Lane 1305, Huajing Road, Xuhui District, Shanghai, P.R. China 200000 Shanghai CHINA Shanghai,China
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745-65-3 Prostaglandin E1

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745-65-3 Fosfestrol sodium

  • Fosfestrol sodium
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,China
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745-65-3 Prostaglandin E1

  • IUPAC NAME-7-[(1R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid MOLECULAR FORMULA-C20H34O5 MOLAR MASS-354.481 g/mol Prostaglandin E1 , known pharmaceutically as alprostadil, is a prostaglandin. It is a drug used in ...
  • India Swapnroop Drugs & Pharmaceuticals [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: 91-240-6641875
  • Fax: 91-240-6641870
  • Address: Plot No: 04, Mayur Park, Harsool Aurangabad,MaharashtraIndia

745-65-3 Alprostadil

  • Alprostadil
  • China Betapharma Shanghai Inc.Co., Ltd [Manufacturer]
  • Tel: 86-21-62951620
  • Fax: 86-21-32230794
  • Address: Jinming Building 12A No. 8 Zunyi(S) Rd. Shanghai China 200336 shanghaiCHINA shanghai,China
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745-65-3 Prostaglandin E 1

  • Prostaglandin E 1, 95.0%Min
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,China
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745-65-3 (s)-(-)-Propranolol hydrochloride

  • (s)-(-)-Propranolol hydrochloride
  • United States RIA International [Manufacturer]
  • Tel: 19735811282
  • Fax: 19735811283
  • Address: 11 Melanie Lane #17 East Hanover 07936 NJ UNITED STATES NJ,United States
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References of Prostaglandin E1
Title: Prostaglandin E1
CAS Registry Number: 745-65-3
CAS Name: (11a,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid
Synonyms: 3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentaneheptanoic acid; alprostadil; PGE1
Manufacturers' Codes: U-10136
Trademarks: Caverject (Pharmacia & Upjohn); Edex (Schwarz); Liple (Mitsubishi); Liprostin (Endovasc); Minprog (Pharmacia); Muse (Meda); Palux (Taisho); Prostandin (Ono); Prostin VR (Pharmacia & Upjohn); Prostivas (Pharmacia & Upjohn)
Molecular Formula: C20H34O5
Molecular Weight: 354.48
Percent Composition: C 67.77%, H 9.67%, O 22.57%
Literature References: A primary prostaglandin; easily crystallized from purified biological extracts. Isoln from sheep seminal vesicle tissue, and structure: Bergstrom et al., Acta Chem. Scand. 16, 501 (1962); eidem, J. Biol. Chem. 238, 3555 (1963). Enzymic conversion from 8,11,14-eicosatrienoic acid: Nugteren et al., Rec. Trav. Chim. 85, 405 (1966). Synthesis of the dl-form: Corey et al., J. Am. Chem. Soc. 90, 3245, 3247 (1968); Schneider et al., ibid. 5895; 91, 5372 (1969); Axen et al., Chem. Commun. 1969, 303; Taub et al., ibid. 1970, 1258; Slates et al., ibid. 1972, 304; Kuo et al., Tetrahedron Lett. 1972, 5317; Taub et al., Tetrahedron 29, 1447 (1973); Miyano, Stealey, Chem. Commun. 1973, 180; Finch et al., J. Org. Chem. 38, 4412 (1973). Synthesis of natural form: Corey et al., J. Am. Chem. Soc. 91, 535 (1969); 92, 2586 (1970); Sih et al., ibid. 94, 3643 (1972); 95, 1676 (1973); Schaaf, Corey, J. Org. Chem. 37, 2921 (1974); Slates et al., Tetrahedron 30, 819 (1974). Metabolism in guinea pigs: Anggard, Samuelsson, J. Biol. Chem. 239, 4097 (1964). Metabolism in humans: Hamberg, Samuelsson, ibid. 246, 6713 (1971). Review of biological activities: Berti et al., Prog. Biochem. Pharmacol. 3, 110 (1967). Comparative pharmacology with respect to other prostaglandins: Weeks, Annu. Rev. Pharmacol. 12, 317 (1972). Clinical use in neonates with cyanotic congenital heart disease: P. M. Olley et al., Adv. Prostaglandin Thromboxane Res. 7, 913 (1980). Use in non-atherosclerotic vasculopathy: D. L. Wooster et al., J. Am. Med. Assoc. 245, 1846 (1981). Clinical trials in impotence: O. I. Linet, F. G. Ogrinc, N. Engl. J. Med. 334, 873 (1996); H. Padma-Nathan et al., ibid. 336, 1 (1997).
Properties: Crystals from ethyl acetate + heptane, mp 115-116°. [a]578 -61.6° (c = 0.56 in tetrahydrofuran). Soly at 35°: 8000 mg/100 ml double distilled water. Easily dehydrated in soln at pHs <4 or >8.
Melting point: mp 115-116°
Optical Rotation: [a]578 -61.6° (c = 0.56 in tetrahydrofuran)
Therap-Cat: Vasodilator (peripheral). In treatment of male erectile dysfunction.
Keywords: Prostaglandin/Prostaglandin Analog; Vasodilator (Peripheral).