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CAS No 55297-95-5 , Tiamulin

  • Name: Tiamulin
  • Synonyms: Tiamulin;(1S,2R,3S,4S,6R,7S,14R)-6-[(2-Diethylaminoethylthio)acetoxy]-3-hydroxy-2,4,7,14-tetramethyl-4-vinyltricyclo[5,4,3,01.8]tetradecan-9-one;
  • CAS Registry Number:
  • Melting Point: 147-148 deg C (after stirring in ethyl acetate and drying at 60 and 80 deg C overnight)
  • Density: 1.1 g/cm3
  • Refractive index: 1.541
  • Safety Statements: Poison by intramuscular and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of SOx and NOx. See also MERCAPTANS.
  • EINECS: 259-580-0
  • Molecular Weight: 493.74
  • InChI: InChI=1/C28H47NO4S/c1-8-26(6)17-22(33-23(31)18-34-16-15-29(9-2)10-3)27(7)19(4)11-13-28(20(5)25(26)32)14-12-21(30)24(27)28/h8,19-20,22,24-25,32H,1,9-18H2,2-7H3/t19?,20-,22+,24-,25-,26+,27-,28-/m0/s1
  • Molecular Formula: C28H47NO4S
  • Molecular Structure:CAS No:55297-95-5 Tiamulin
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55297-95-5 Acetic acid,2-[[2-(diethylamino)ethyl]thio]-,(3aS,4R,5S,6S,8R,9S,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-ylester

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi null,ShanXiChina
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55297-95-5 Tiamulin

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55297-95-5 Tiamuline

  • China Kouting Chemical Co.,Ltd [Importer/Exporter]
  • Tel: +86-(21)-58116473
  • Fax: +86-(21)-61094103
  • Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318, shanghai,shanghaiChina
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55297-95-5 TIAMULIN

  • China HANGZHOU THINK CHEMICAL CO. [Manufacturer]
  • Tel: +86-571-81956191/ +86-571-81956192
  • Fax: +86-571-81956190
  • Address: 425 MOGAN HILL ROAD ,
    HANGZHOU, 310011 CHINA null,nullChina
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55297-95-5 TIAMULINE

  • China Xingcheng Chempharm Co., Ltd [Manufacturer]
  • Tel: +86-576-88525005/ +86-576-88886292
  • Fax: +86-576-88225056
  • Address: B Area, 10F, Yaoda Mansion, 289, Shifu Road, Taizhou, Zhejiang, China 318000 null,nullChina
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55297-95-5 Tiamuline

  • China TaiZhou HiKong Chemical Co., Ltd. null
  • Tel: +86-18967213045,13957694715
  • Fax: +86-(580)-6033180,6034626
  • Address: Taizhou Economic Technical Development Zone, Taizhou, Zhejiang 318000, null,nullChina
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55297-95-5 Tiamulin

  • United States CBSCHEM LIMITED null
  • Fax: (888) 557-9843
  • Address: 621 South 48th Street, Suite 115,Tempe, AZ 85281 null,nullUnited States
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55297-95-5 TIAMULIN

  • China Taizhou Creating Chemical Co.,Ltd [Manufacturer]
  • Tel: +86-576-88827176/ +86-576-88820069
  • Fax: +86-576-88822496
  • Address: B Suite 12F,
    Jiangbin Building,Jiaojiang,Taizhou,
    Zhejiang China null,nullChina
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55297-95-5 Tiamulin

  • China Chemfar Ltd. null
  • Fax: 86-571-87859289
  • Address: 16E,Huarong Times Mansion, No.3880 Jiangnan Avenue, Binjiang District, Hangzhou, China null,nullChina
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References of Tiamulin
Title: Tiamulin
CAS Registry Number: 55297-95-5
CAS Name: (3aS,4R,5S,6S,8R,9R,9aR,10R)-[[2-(Diethylamino)ethyl]thio]acetic acid 6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester
Synonyms: 14-desoxy-14-[(2-diethylaminoethyl)mercaptoacetoxy]mutilin; thiamutilin
Manufacturers' Codes: SQ-14055
Molecular Formula: C28H47NO4S
Molecular Weight: 493.74
Percent Composition: C 68.11%, H 9.59%, N 2.84%, O 12.96%, S 6.49%
Literature References: Derivative of pleuromutilin, q.v. Prepn: H. Egger, DE 2248237 corresp to US 3919290 (1973, 1975 both to Sandoz); H. Egger, H. Reinshagen, J. Antibiot. 29, 915 (1976). Biosynthesis: F. Knauseder, E. Brandl, ibid. 125. In vitro activity: H. Werner et al., ibid. 31, 756 (1978). Metabolism: J. Dreyfuss et al., ibid. 32, 496 (1979). Effect vs Mycoplasma: C. O. Baughn et al., Avian Dis. 22, 620 (1978); R. F. Goodwin, Vet. Rec. 104, 194 (1979). Mechanism of action: G. H?genauer in Antibiotics vol. 5(pt. 1), F. E. Hahn, Ed. (Springer-Verlag, New York, 1979) pp 344-360. Treatment of swine dysentery: M. D. Anderson, Vet. Med. Small Anim. Clin. 78, 98 (1983).
 
Derivative Type: Fumarate
CAS Registry Number: 55297-96-6
Manufacturers' Codes: 81723 hfu; SQ-22947
Trademarks: Denagard (Novartis); Dynamutilin (Novartis); Tiamutin (Novartis)
Molecular Formula: C32H51NO8S
Molecular Weight: 609.81
Percent Composition: C 63.03%, H 8.43%, N 2.30%, O 20.99%, S 5.26%
Properties: Crystals from acetone, mp 147-148° (after stirring in ethyl acetate and drying at 60° and 80° overnight).
Melting point: mp 147-148° (after stirring in ethyl acetate and drying at 60° and 80° overnight)
 
Therap-Cat-Vet: Antibacterial.