Home > Name List By 6 > 6-chloro-1,1-dioxo-3-(prop-2-enylsulfanylmethyl)-3,4-dihydro-2H-1λ

CAS No 5588-16-9 , 6-chloro-1,1-dioxo-3-(prop-2-enylsulfanylmethyl)-3,4-dihydro-2H-1λ

  • Name: 6-chloro-1,1-dioxo-3-(prop-2-enylsulfanylmethyl)-3,4-dihydro-2H-1λ
  • Synonyms: DSSTox_CID_25857; Althiazide [USAN];Altizide; DSSTox_RID_81178; Althiazide (USAN); P-1779; 5588-16-9;6,
    2,4-benzothiadiazine-7-sulfonamide; DSSTox_GSID_45857;6-chloro-1,1-dioxo-3-(prop-2-enylsulfanylmethyl)-3,4-dihydro-2H-1λ NCGC00094855-01;
  • CAS Registry Number:
  • Flash Point: 332.3°C
  • Boiling Point: 625.8°Cat760mmHg
  • Density: 1.502g/cm3
  • Refractive index: 1.613
  • Flash Point: 332.3°C
  • EINECS: 226-994-8
  • Molecular Weight: 383.89456
  • InchiKey: VGLGVJVUHYTIIU-UHFFFAOYSA-N
  • InChI: InChI=1S/C11H14ClN3O4S3/c1-2-3-20-6-11-14-8-4-7(12)9(21(13,
    16)17)5-10(8)22(18,19)15-11/h2,4-5,11,14-15H,1,3,6H2,(H2,13,16,17)
  • Molecular Formula: C11H14ClN3O4S3
  • Molecular Structure:CAS No:5588-16-9 6-chloro-1,1-dioxo-3-(prop-2-enylsulfanylmethyl)-3,4-dihydro-2H-1λ

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References of 6-chloro-1,1-dioxo-3-(prop-2-enylsulfanylmethyl)-3,4-dihydro-2H-1λ
Title: Althiazide
CAS Registry Number: 5588-16-9
CAS Name: 6-Chloro-3,4-dihydro-3-[(2-propenylthio)methyl]-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Synonyms: 3-[(allylthio)methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; 3-allylthiomethyl-6-chloro-7-sulfamoyl-3,4-dihydrobenzothiadiazine 1,1-dioxide; 6-chloro-3,4-dihydro-7-sulfamoyl-3-(2-thiapent-4-enyl)-2H-1,2,4-benzothiadiazine 1,1-dioxide; altizide
Manufacturers' Codes: P-1779
Molecular Formula: C11H14ClN3O4S3
Molecular Weight: 383.89
Percent Composition: C 34.42%, H 3.68%, Cl 9.24%, N 10.95%, O 16.67%, S 25.06%
Literature References: Prepn: GB 902658; W. M. McLamore, G. D. Laubach, US 3111517 (1962, 1963 both to Pfizer). HPLC determn in tablets: F. DeCroo et al., J. Chromatogr. 329, 422 (1985). Clinical evaluation in hypertension: G. Simon et al., Curr. Ther. Res. 46, 44 (1989).
Properties: Solid, mp 206-207°.
Melting point: mp 206-207°
NOTE: Combination with spironolactone, Aldactazine (Searle) .
Therap-Cat: Diuretic; antihypertensive.
Keywords: Antihypertensive; Thiazides and Analogs; Diuretic; Thiazides and Analogs.