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CAS No 57-63-6 , Ethynyl estradiol

  • Name: Ethynyl estradiol
  • Synonyms: oradiol; Ethynyl estradiol; lynoral; 19-nor-17alpha-pregna-1,3,5(10)-trien-20-yne-3,17,diol; perovex; dyloform; estoral (orion); novestrol; chee-o-genf; 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17alpha)-; anovlar; diogyn-e; roldiol; primogyn; estroals; ylestrol; feminone; estinyl; ginestrene; esteed; linoral; 17alpha-ethynyl-3,17-dihydroxy-delta-(sup1,3,5)-estratriene; 17alpha-Ethynyl-3-hydroxy-1,3,5(10)-estratrien-17beta-ol; etinestryl; eticyclol; amenoron; ethinoral; palonyl; etinestrol; EE; menolyn; neo-estrone;17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol; estigyn; diognat-e; ethinyloestradiol; orestralyn; inestra; progynon c; estra-1,3,5(10)-triene-3,17beta-diol, 17alpha-ethynyl-; Estone;17a-ethynyl-1,3,5(10)-estratriene-3,17b-diol; eticyclin; ethidol; primogyn c(or m); 3,17beta-dihydroxy-17alpha-ethynyl-1,3,5(10)-estratriene; 17-ethynyl estradiol;Ethynyl estradiol; spanestrin;
  • CAS Registry Number:
  • Melting Point: 182-183 ºC
  • Flash Point: 211.2°C
  • Boiling Point: 457.2°Cat760mmHg
  • Density: 1.21g/cm3
  • Refractive index: -30 ° (C=0.4, Pyridine)
  • Water Solubility: ethanol: 50 mg/mL, clear, slightly yellow
  • Safety Statements: R45;R22
  • Hazard Symbols: T: Toxic;
  • Flash Point: 211.2°C
  • EINECS: 200-342-2
  • Molecular Weight: 296.41
  • InChI: InChI=1/C20H24O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,5,7,12,16-18,21-22H,4,6,8-11H2,2H3/t16-,17-,18+,19+,20+/m1/s1
  • Risk Statements: S53;S36/37/39;S45
  • Molecular Formula: C20H24O2
  • Molecular Structure:CAS No:57-63-6 Ethynyl estradiol
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57-63-6 Ethynyl estradiol

  • Ethynyl estradiol Synonyms:NOVESTROL;NEO-ESTRONE;ETHYNYLESTRADIOL;ETHINYL ESTRADIOL;LYNORAL;17ALPHA-ETHYNYL-DELTA1,3,5(10)-ESTRA-TRIENE-3,17BETA-DIOL;17ALPHA-ETHYNYLESTRADIOL;17ALPHA-ETHINYLESTRADIOL CAS:57-63-6 MF:C20H24O2 MW:296.4 EINECS:200-342-2 ...
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57-63-6 57-63-6 High Purity of Female Hormones Powder Ethinylestradiol

  • Ethinylestradiol Synonyms:NOVESTROL;NEO-ESTRONE;ETHYNYLESTRADIOL;ETHINYL ESTRADIOL; Product Categories:steriods CAS NO: 57-63-6 EINECS:200-342-2 Molecular Weight: 296.41 Molecular Formula: C20H24O2 Apparence:white powder Standard: USP28 Usage:estroge...
  • China Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd. [Manufacturer, Trading Company]
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  • Address: No. 388, Huangshan Rd, Tianyuan District, Zhuzhou City, Hunan Province, P.R.China. zhuzhou,HunanChina
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57-63-6 high quality Ethinylestradiol powder

  • Product name: High Purity Ethynyl Estradiol / Ethinylestradiol (CAS No.: 57-63-6) CAS: NO. 57-63-6 Molecular Formula: C20H24O2 Molecular Weight: 296.41 Standard: USP30 Appearance: White powder Melting Point: 180~186 Loss on drying: ≤ 1.0% Assay: 97....
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  • China Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd. [Manufacturer]
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  • Address: No. 388, Huangshan Rd, Tianyuan District zhuzhou,HunanChina
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57-63-6 high quality Ethinylestradiol powder

  • CAS: NO. 57-63-6 Molecular Formula: C20H24O2 Molecular Weight: 296.41 Standard: USP30 Appearance: White powder Melting Point: 180~186 Loss on drying: ≤ 1.0% Assay: 97.0~102.0 Packing: 5kg/tin Description: Ethinylestradiol is a man-made form of the n...
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  • China Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd. [Manufacturer]
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  • Address: No. 388, Huangshan Rd, Tianyuan District Zhuzhou,HunanChina
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57-63-6 Top quality Ethynyl estradiol skype:tracyxu123

  • Top quality Ethynyl estradiol Synonyms: Amenoron; Esteed; Estoral; Estorals; Ethinoral; Ethynylestradiol; Ethynyloestradiol; Eticyclin; Eticyclol CAS No.: 57-63-6 Formula: C20H24O2 Molecular Weight: 296.44 EINECS: 200-342-2 Density: 1.21 g/cm3 Meltin...
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57-63-6 Ethynyl Estradiol

  • Ethynyl Estradiol Synonyms:Novestrol;Neo-estrone;Ethynylestradiol;Ethinyl estradiol;Lynoral;17alpha-ethynyl-delta1,3,5(10)-estra-triene-3,17beta-diol;17alpha-ethynylestradiol;17alpha-ethinylestradiol CAS:57-63-6 MF:C20H24O2 MW:296.4 EINECS:200-342-2 ...
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  • China Hubei Yuancheng Saichuang Technology Co.,Ltd. [Manufacturer]
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57-63-6 Ethynyl estradiol CAS: 57-63-6

  • Ethynyl estradiol CAS: 57-63-6 Product Name: Ethynyl estradiol Synonyms: NOVESTROL;NEO-ESTRONE;ETHYNYLESTRADIOL;ETHINYL ESTRADIOL;LYNORAL CAS: 57-63-6 MF: C20H24O2 MW: 296.4 EINECS: 200-342-2 Product Categories: Alcohols and Derivatives;Steroids;Acet...
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57-63-6 Ethinylestradiol

  • Ethinylestradiol Synonyms: NOVESTROL; NEO-ESTRONE; ETHYNYLESTRADIOL CAS NO: 57-63-6 Molecular Weight: 296.41 Molecular Formula: C20H24O2 Appearance: Off-White to Light-Yellow Crystalline Powder Usage: A metabolite of 17alpha-Ethynylestradiol A synthe...
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  • China Hubei Yuancheng Pharmaceutical Tech. Co., Ltd. [Manufacturer]
  • Tel: 86-027-50756235
  • Address: No.496,Zhongshan Road wuhan,HubeiChina
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57-63-6 Ethinylestradiol

  • CAS NO: 57-63-6 Molecular Weight: 296.41 Molecular Formula: C20H24O2 EINECS:200-342-2 density:1.21g/cm3 melting point:182-183℃ boiling point:457.2°C at 760 mmHg flash(ing) point:211.2°C vapour pressure:3.74E-09mmHg at 25°C physico-chemical property:...
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  • Address: No.496,Zhongshan Road, Wuhan, Hubei, China Wuhan,HubeiChina
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57-63-6 Ethinylestradiol

  • Ethinylestradiol CAS NO: 57-63-6 Molecular Weight: 296.41 Molecular Formula: C20H24O2 Standard: USP28
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  • China Wuhan Hezhong Bio-Chemical Manufature Co.,Ltd [Manufacturer]
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References of Ethynyl estradiol
Title: Ethinyl Estradiol
CAS Registry Number: 57-63-6
CAS Name: (17a)-19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol
Synonyms: 17a-ethynyl-1,3,5(10)-estratriene-3,17b-diol; 17-ethinylestradiol; ethynylestradiol
Trademarks: Estinyl (Schering-Plough); Feminone (Pharmacia & Upjohn); Lynoral (Organon); Orestralyn (McNeil); Primogyn C (Schering AG); Progynon C (Schering AG)
Molecular Formula: C20H24O2
Molecular Weight: 296.40
Percent Composition: C 81.04%, H 8.16%, O 10.80%
Literature References: Synthetic steroid with high oral estrogenic potency: Inhoffen, Hohlweg, Naturwissenschaften 26, 96 (1938). Prepn from estrone: Inhoffen et al., Ber. 71, 1024 (1938). See also DE 702063; GB 516444; US 2243887; US 2251939; US 2265976; US 2267257. Properties: Petit, Muller, Bull. Soc. Chim. Fr. 1951, 121; L. Ehmann, A. Wettstein, Pharm. Acta Helv. 25, 297 (1950). NMR: Hampel, Kraemer, Ber. 98, 3255 (1965). Toxicity: E. I. Goldenthal, Toxicol. Appl. Pharmacol. 18, 185 (1971). Randomized double-blind clinical studies: S. Koetsawang et al., Contraception 25, 231 (1982); A. Sheth et al., ibid. 243. Clinical evaluation in gonadal dysgenesis: L. Cuttler et al., J. Clin. Endocrinol. Metab. 60, 1087 (1985). General review: K. W. Thompson, J. Clin. Pharmacol. 8, 1088-1098 (1948). Review of metabolism and pharmacokinetics: K. Fotherby, Methods Find. Exp. Clin. Pharmacol. 4, 133-141 (1982); of carcinogenicity studies: IARC Monographs 21, 233-255 (1979); ibid. Suppl. 4, 186-188 (1982).
 
Derivative Type: Hemihydrate
Properties: Fine needles from methanol + water, mp 141-146°, [a]D25 0 ± 1° (dioxane). Dehydrates after melting and further heating, mp 182-184°. [a]D24 +3.5 ± 0.5° (c = 2 in dioxane); -29.5 ± 1° (c = 2 in pyridine). uv max (ethanol): 281 nm (e 2040 ± 60). Practically insol in water. Soly: 1 part in 6 of ethanol, 1 in 4 of ether, 1 in 5 of acetone, 1 in 4 of dioxane, and 1 in 20 of chloroform. Sol in vegetable oils, and in solns of fixed alkali hydroxides. LD50 in rats, mice (mg/kg): 2952, 1737 orally (Goldenthal).
Melting point: mp 141-146°; mp 182-184°
Optical Rotation: [a]D25 0 ± 1° (dioxane); [a]D24 +3.5 ± 0.5° (c = 2 in dioxane); -29.5 ± 1° (c = 2 in pyridine)
Absorption maximum: uv max (ethanol): 281 nm (e 2040 ± 60)
Toxicity data: LD50 in rats, mice (mg/kg): 2952, 1737 orally (Goldenthal)
 
Derivative Type: 3-Acetate
Molecular Formula: C22H26O3
Molecular Weight: 338.44
Percent Composition: C 78.07%, H 7.74%, O 14.18%
Properties: Crystals, mp 152-153°. [a]D20 +3° (chloroform).
Melting point: mp 152-153°
Optical Rotation: [a]D20 +3° (chloroform)
 
Derivative Type: 3-Benzoate
Molecular Formula: C27H28O3
Molecular Weight: 400.51
Percent Composition: C 80.97%, H 7.05%, O 11.98%
Properties: Needles from methanol, mp 200-202°.
Melting point: mp 200-202°
 
NOTE: Also used in combination with chlormadinone acetate, desogestrel, ethynodiol, gestodene, lynestrenol, norethindrone or norgestrel, q.q.v. Has been used in combination with dimethisterone, medroxyprogesterone, or megestrol acetate, q.q.v.
CAUTION: These substances are listed as known human carcinogens: Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-115.
Therap-Cat: Estrogen. In combination with progestogen as oral contraceptive.
Therap-Cat-Vet: Estrogen.
Keywords: Contraceptive (Oral); Estrogen; Steroidal.