Home > Name List By other > (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R, 5R)-5-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6, 7-hexahydro-1H-inden-4-yl...

CAS No 57333-96-7 , (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,
5R)-5-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,
7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,
3-diol

  • Name: (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,
    5R)-5-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,
    7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,
    3-diol
  • Synonyms: (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,
    5R)-5-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,
    7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,
    3-diol; TV-02; Curatoderm; TV-02H; 57333-96-7; Bonalfa; 1-alpha,24(R)-Dihydroxyvitamin D3;tacalcitol;
  • CAS Registry Number:
  • Density: 1.06
  • Refractive index: 1.545
  • Molecular Weight: 416.63646
  • InchiKey: BJYLYJCXYAMOFT-RSFVBTMBSA-N
  • InChI: InChI=1S/C27H44O3/c1-17(2)25(29)13-8-18(3)23-11-12-24-20(7-6-14-27(23,
    24)5)9-10-21-15-22(28)16-26(30)19(21)4/h9-10,17-18,22-26,28-30H,4,6-8,
    11-16H2,1-3,5H3/b20-9+,21-10-/t18-,22-,23-,24+,25-,26+,27-/m1/s1
  • Molecular Formula: C27H44O3
  • Molecular Structure:CAS No:57333-96-7 (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,<br />5R)-5-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,<br />7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,<br />3-diol
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57333-96-7 (1ALPHA,3BETA,5Z,7E,24R)-9,10-SECOCHOLESTA-5,7,10 (19)-TRIENE,1,3,24-TRIOL

  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany ,Germany
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57333-96-7 Tacalcitol

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57333-96-7 TACALCITOL

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 ,United States
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57333-96-7 Exemestane

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57333-96-7 TACALCITOL

  • China Chemvon Biotechnology Co. Ltd. [Manufacturer]
  • Tel: +86-21-50790412
  • Fax: +86-21-50790419
  • Address: Room 403, Suite 2, 720 Cailun Road,
    Zhangjiang Hi-Tech Park in Pudong District, Shanghai 201203, China ,China
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57333-96-7 TACALCITOL

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China ,China
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References of (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,
5R)-5-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,
7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,
3-diol
Title: Tacalcitol
CAS Registry Number: 57333-96-7
CAS Name: (1a,3b,5Z,7E,24R)-9,10-Secocholesta-5,7,10(19)-triene-1,3,24-triol
Synonyms: 1a,24(R)-dihydroxycholecalciferol; 1a,24R-dihydroxyvitamin D3
Manufacturers' Codes: TV-02
Trademarks: Bonealfa (Teijin); Curatoderm (Merck KGaA)
Molecular Formula: C27H44O3
Molecular Weight: 416.64
Percent Composition: C 77.83%, H 10.64%, O 11.52%
Literature References: Bioactive, synthetic vitamin D3 analog; exhibits antiproliferative effect on keratinocytes. Prepn: T. Takeshita et al., DE 2526981; eidem, US 4022891 (1976, 1977 both to Teijin); M. Morisaki et al., J. Chem. Soc. Perkin Trans. 1 1975, 1421; K. Ochi et al., ibid. 1979, 165. Pharmacology: T. Matsunaga et al., J. Dermatol. 17, 135 (1990). Clinical evaluation in psoriasis: M. J. P. Gerritsen et al., Br. J. Dermatol. 131, 57 (1994). Review: M. Nishimura et al., Eur. J. Dermatol. 3, 255-261 (1993).
Properties: White solid. uv max (ethanol): 265 nm.
Absorption maximum: uv max (ethanol): 265 nm
Therap-Cat: Antipsoriatic.
Keywords: Antipsoriatic.