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CAS No 57460-41-0 , talinolol

  • Name: talinolol
  • Synonyms: 1-(3-(3-Cyclohexylureido)phenoxy)-3-(tert-butylamino)-2-propanol;( -)-1-(4-(3-(tert-Butylamino)-2-hydroxypropoxy)phenyl)-3-cyclohexylharnstoff;talinolol;Racemic talinolol;rac-Talinolol;Cordanum;1-(4-(Cyclohexylureido)phenoxy)-3-(tert-butylamino)-2-propanol;(+-)-1-(p-(3-(tert-Butylamino)-2-hydroxypropoxy)phenyl)-3-cyclohexylurea;1-(4-Cyclohexylureidophenoxy)-2-hydroxy-3-tert-butylaminopropane;
  • CAS Registry Number:
  • Flash Point: 268.3°C
  • Boiling Point: 520°C at 760 mmHg
  • Density: 1.11g/cm3
  • Refractive index: 1.552
  • Flash Point: 268.3°C
  • Molecular Weight: 363.499
  • InChI: InChI=1S/C20H33N3O3/c1-20(2,3)21-13-17(24)14-26-18-11-9-16(10-12-18)23-19(25)22-15-7-5-4-6-8-15/h9-12,15,17,21,24H,4-8,13-14H2,1-3H3,(H2,22,23,25)
  • Molecular Formula: C20H33N3O3
  • Molecular Structure:CAS No:57460-41-0 talinolol
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57460-41-0 TALINOLOL

  • United States 2A PharmaChem USA [Manufacturer]
  • Tel: 630-322-8887
  • Fax: 630-322-8885
  • Address: 2A PharmaChem USA
    5403 Patton Drive, Suite 208
    Lisle, Illinois 60532 null,nullUnited States
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57460-41-0 TALINOLOL

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of talinolol
Title: Talinolol
CAS Registry Number: 57460-41-0
CAS Name: N-Cyclohexyl-N¢-[4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]phenyl]urea
Synonyms: 1-(4-cyclohexylureidophenoxy)-2-hydroxy-3-tert-butylaminopropane; (±)-1-[p-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl]-3-cyclohexylurea
Manufacturers' Codes: 02-115
Trademarks: Cordanum (AWD)
Molecular Formula: C20H33N3O3
Molecular Weight: 363.49
Percent Composition: C 66.09%, H 9.15%, N 11.56%, O 13.20%
Literature References: Selective b1-adrenergic blocker structurally related to practolol, q.v. Prepn: R. Eckardt et al., DE 2153024 (1972 to Arzneimittelwerke VEB), C.A. 77, 61639b (1972); idem et al., Pharmazie 30, 633 (1975). Series of articles on pharmacology, toxicology: ibid. 638-683. Acute toxicity: K. Femmer et al., ibid. 642. Clinical pharmacokinetics and bioavailability: B. Trausch et al., Biopharm. Drug Dispos. 16, 403 (1995). Review of clinical experience: I. Assmann, Curr. Med. Res. Opin. 13, 325-342 (1995).
Properties: Cryst from isopropanol, mp 142-144°. LD50 in rats, mice (mg/kg): 1180, 593 orally; 54.3, 74.7 i.p.; 29.7, 25.0 i.v. (Femmer).
Melting point: mp 142-144°
Toxicity data: LD50 in rats, mice (mg/kg): 1180, 593 orally; 54.3, 74.7 i.p.; 29.7, 25.0 i.v. (Femmer)
Therap-Cat: Antihypertensive; antiarrhythmic.
Keywords: ?Adrenergic Blocker; Antiarrhythmic; Antihypertensive; Aryloxypropanolamine Derivatives.