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CAS No 58337-35-2 , 2,5,11-trimethyl-6H-pyrido[4,3-b]carbazol-2-ium-9-ol

  • Name: 2,5,11-trimethyl-6H-pyrido[4,3-b]carbazol-2-ium-9-ol
  • Synonyms: ELLIPTINIUM ACETATE; Elliptinium acetate [INN:BAN];2,5,11-trimethyl-6H-pyrido[4,3-b]carbazol-2-ium-9-ol;acetate; Elliptinii acetas [INN-Latin];Celiptium; Ellipticine acetomethylate;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: g/cm3
  • Flash Point: °C
  • EINECS: 261-216-0
  • Molecular Weight: 336.3844
  • InchiKey: BOMZMNZEXMAQQW-UHFFFAOYSA-N
  • InChI: InChI=1S/C18H16N2O.C2H4O2/c1-10-15-9-20(3)7-6-13(15)11(2)18-17(10)14-8-
    12(21)4-5-16(14)19-18;1-2(3)4/h4-9,21H,1-3H3;1H3,(H,3,4)
  • Molecular Formula: C20H20N2O3
  • Molecular Structure:CAS No:58337-35-2 2,5,11-trimethyl-6H-pyrido[4,3-b]carbazol-2-ium-9-ol

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References of 2,5,11-trimethyl-6H-pyrido[4,3-b]carbazol-2-ium-9-ol
Title: Elliptinium Acetate
CAS Registry Number: 58337-35-2
CAS Name: 9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]carbazolium acetate (salt)
Synonyms: 9-hydroxy-2-methylellipticinium acetate; HME
Manufacturers' Codes: NSC-264137
Trademarks: Celiptium (Sanofi-Aventis)
Molecular Formula: C20H20N2O3
Molecular Weight: 336.38
Percent Composition: C 71.41%, H 5.99%, N 8.33%, O 14.27%
Literature References: Deriv of ellipticine, q.v., with anticancer activity. Prepn: J. LePecq et al., DE 2618223; J. B. LePecq, C. Paoletti, US 4310667 (1976, 1982 both to Agence Nat. Valorisation Recher.). Activity vs L 1210 mouse leukemia: eidem, C.R. Seances Acad. Sci. Ser. D 281, 1365 (1975). HPLC determn: G. Muzard, J. B. LePecq, J. Chromatogr. 169, 446 (1979). Metabolism, disposition: N. Van-Bac et al., Cancer Treat. Rep. 64, 879 (1980). Antitumor activity, pharmacology, toxicity study: C. Paoletti et al., Recent Results Cancer Res. 74, 107 (1980). Use in treatment of breast cancers: J. Rouesse et al., Bull. Cancer 68, 437 (1981). Cytochemical and autoradiographic study: N. Sales, E. Puvion, Eur. J. Cancer Clin. Oncol. 18, 291 (1982).
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Alkaloids/Natural Products.