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CAS No 59-43-8 , 2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,

  • Name: 2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,
  • Synonyms: Thiamine monochloride; Aneurine;2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,
    3-thiazol-3-ium-5-yl]ethanol; Oryzanin; Tiamina;chloride; Beivon; Oryzanine;vitamin B1; Thiaminum; Bethiamin; 59-43-8;
  • CAS Registry Number:
  • Melting Point: 128 - 129
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: g/cm3
  • Safety Statements: Poison by subcutaneous and intravenous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of NOx, SOx, and Cl.
  • Flash Point: °C
  • EINECS: 200-425-3
  • Molecular Weight: 300.80758
  • InChI: InChI=1S/C12H17N4OS.ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)
  • Molecular Formula: C12H17ClN4OS
  • Molecular Structure:CAS No:59-43-8 2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,<br />3-thiazol-3-ium-5-yl]ethanol
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59-43-8 Vitamin B1 (Thiamine Chloride) (4,5,4-Methyl-13C3, 99%)

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59-43-8 Thiamine Hydrochloride

  • Thiamine Hydrochloride can be used to treat Vitamin B1 deficiency. With the development of clinical pharmacology in recent years, Vitamin B1 is found to be helpful in treating many other diseases.It is an essential ingredient for compound feed, and i...
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59-43-8 aflatoxinb1

  • REAGEN? Aflatoxin B1 ELISA Test Kit is a competitive enzyme immunoassay for the quantitative analysis of Aflatoxin B1 in cereals, meat/fish, feed, milk,milk powder ,oils,peanuts and pistachios .The unique features of the kit are: ? High recovery (80-...
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59-43-8 Vitamin B1 Thiamine chloride

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59-43-8 Pharm grade Vitamin B1

  • ProName: Pharm grade Vitamin B1 Aneurin; Antiberiberi factor; Biamine; Betalin S; Betamin; Beta-Sol; Thiamine chloride; 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride Product Details: Place of Origin...
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  • China Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd. [Manufacturer]
  • Tel: 86-181-88938010
  • Address: No. 388, Huangshan Rd, Tianyuan District, Zhuzhou City, Hunan Province, P.R.China. Zhuzhou,HunanChina
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59-43-8 thiamine

  • China Taiyuan RHF CO., ltd. [Manufacturers]
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59-43-8 Thiamine, 99%

  • Thiamine, 99%
  • Belgium Alkemi [Manufacturer]
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59-43-8 Thiamine Mononitrate (Vitamin B1 Mononitrate)

  • China Simag Chemicals [Manufacturer]
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59-43-8 Vitamin B1

  • China Kouting Chemical Co.,Ltd [Importer/Exporter]
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59-43-8 Vitamin B1

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References of 2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,
Title: Thiamine
CAS Registry Number: 59-43-8
CAS Name: 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium chloride
Synonyms: vitamin B1; aneurin; thiamine monochloride; thiaminium chloride
Molecular Formula: C12H17ClN4OS
Molecular Weight: 300.81
Percent Composition: C 47.91%, H 5.70%, Cl 11.79%, N 18.63%, O 5.32%, S 10.66%
Literature References: Essential nutrient required for carbohydrate metabolism; also involved in nerve function. Biosynthesized by microorganisms and plants. Dietary sources include whole grains, meat products, vegetables, milk, legumes and fruit. Also present in rice husks and yeast. Converted in vivo to thiamine diphosphate, a coenzyme in the decarboxylation of a-keto acids. Chronic deficiency may lead to neurological impairment, beriberi, Wernicke-Korsakoff syndrome. Isoln from rice bran: B. C. P. Jansen, W. F. Donath, Chem. Weekbl. 23, 201 (1926). Structure: R. R. Williams, J. Am. Chem. Soc. 58, 1063 (1936); R. R. Williams, J. K. Cline, ibid. 1504; R. R. Williams et al., ibid. 59, 526 (1937). Review of syntheses: Knobloch in H. Vogel, Chemie und Technik der Vitamine vol. II (Stuttgart, 1953) pp 1-128. Toxicity data: D. Winter et al., Int. Z. Vitaminforsch. 37, 82 (1967). HPLC determn in foods, pharmaceuticals, body tissues: T. Kawaski, Methods Enzymol. 122, 15 (1986); in plasma and pharmacokinetics: H. Mascher, C. Kikuta, J. Pharm. Sci. 82, 56 (1993). Review of bioavailability, absorption, and role in nutrition: F. L. Iber et al., Am. J. Clin. Nutr. 36, 1067-1082 (1982). Reviews: "Thiamin: Twenty Years of Progress", Ann. N.Y. Acad. Sci. 378, H. Z. Sable, C. J. Grubier, Eds. (1982) 470 pp; "Thiamin, Vitamin B1, Aneurin" in Vitamins, W. Friedrich, Ed. (de Gruyter, Berlin, 1988) pp 339-401.
Derivative Type: Hydrochloride
CAS Registry Number: 67-03-8
Synonyms: Thiamine chloride hydrochloride; thiamine dichloride
Trademarks: Benerva (Roche); Betabion (Merck KGaA); Betalin S (Lilly); Betaxin (Sterling Winthrop); Bewon (Wyeth); Metabolin (Takeda); Vitaneurin (Mepha)
Molecular Formula: C12H17ClN4OS.HCl
Molecular Weight: 337.27
Percent Composition: C 42.73%, H 5.38%, Cl 21.02%, N 16.61%, O 4.74%, S 9.51%
Literature References: Comprehensive description: K. A. M. Al-Rashood et al., Anal. Profiles Drug Subs. 18, 413-458 (1989).
Properties: Monoclinic plates in rosette-like clusters. Slight thiazole odor. Bitter taste. dec 248°. One gram dissolves in ~1 ml water, 18 ml glycerol, 100 ml 95% alcohol, 315 ml abs alcohol; more sol in methanol. Sol in propylene glycol. Practically insol in ether, benzene, hexane, chloroform. pH of a 1% w/v soln in water 3.13; pH of a 0.1% w/v soln in water 3.58. On exposure to air of average humidity, the vitamin absorbs an amount of water corresponding to nearly one mol, forming a hydrate. LD50 in mice (mg/kg): 89.2 i.v.; 8224 orally (Winter).
Toxicity data: LD50 in mice (mg/kg): 89.2 i.v.; 8224 orally (Winter)
Derivative Type: Mononitrate
CAS Registry Number: 532-43-4
Molecular Formula: C12H17N5O4S
Molecular Weight: 327.36
Percent Composition: C 44.03%, H 5.23%, N 21.39%, O 19.55%, S 9.80%
Literature References: Prepn: R. J. Turner, G. J. Schmitt, US 2844579 (1958 to Am. Cyanamid).
Properties: Crystals, mp 196-200° (dec). Practically nonhygroscopic. pKa 4.8. Soly in water (g/100 ml): 2.7 (25°); ~30 (100°). pH of 2% aq soln 6.5 to 7.1. More stable than the hydrochloride; suitable for enrichment of flours and feeds, multivitamin prepns.
Melting point: mp 196-200° (dec)
pKa: pKa 4.8
Therap-Cat: Vitamin (enzyme cofactor).
Therap-Cat-Vet: Vitamin (enzyme cofactor).
Keywords: Enzyme Cofactor; Vitamin/Vitamin Source; Vitamin B1.