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CAS No 59227-89-3 , 1-dodecylazepan-2-one

  • Name: 1-dodecylazepan-2-one
  • Synonyms: Tranzone; 59227-89-3; N-Dodecylcaprolactam; 1-dodecylazepan-2-one;Azone;1-dodecylazepan-2-one; N-Lauryl caprolactam; 1-Dodecylazacycloheptan-2-one;
  • CAS Registry Number:
  • Melting Point: -7 deg C
  • Boiling Point: 350
  • Density: 0.906-0.926
  • Refractive index: 1.470-1.473
  • Water Solubility: Insoluble in water, and form emulsions with water, soluble in various organic solvents.
  • EINECS: 261-668-9
  • Molecular Weight: 281.4766
  • InchiKey: AXTGDCSMTYGJND-UHFFFAOYSA-N
  • InChI: InChI=1S/C18H35NO/c1-2-3-4-5-6-7-8-9-10-13-16-19-17-14-11-12-15-18(19)
    20/h2-17H2,1H3
  • Molecular Formula: C18H35NO
  • Molecular Structure:CAS No:59227-89-3 1-dodecylazepan-2-one
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59227-89-3 Laurocapram

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi null,ShanXiChina
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59227-89-3 Laurocapram

  • United States HBCChem, Inc. [Manufacturers]
  • Tel: +1-510-219-6317
  • Fax: +1-510-675-0318
  • Address: null Union City,CaliforniaUnited States
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59227-89-3 Laurocapram

  • China Xilin Chemical Group Co., Ltd null
  • Tel: +86-(0)-15527136576
  • Fax: +86-(27)-83820093
  • Address: 16# Luojiashan, Wuchang District, Wuhan, Hubei 430071, null,nullChina
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59227-89-3 Laurocapram

  • Laurocapram
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,nullChina
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59227-89-3 Laurocapram

  • China Shanghai Fchemicals Technology Co., Ltd. [Manufacturers]
  • Tel: +86-(21)-36030322
  • Fax: +86-(21)-66315383
  • Address: Room524,Hua-Rui Mansion No.18 Jiang Chang Yi Road, Shanghai 200436, Shanghai,ShanghaiChina
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59227-89-3 N-Dodecyl caprolactam

  • China Hainan Zhongxin Chemical Co., Ltd. [Manufacturer]
  • Tel: + 86 898 6854 0310/ + 86 21 64361616
  • Fax: + 86 898 6854 0119
  • Address: HAINAN COMPANY
    Address: Rm 811, Hainan Mandarin Hotel,
    Binhai Avenue, Haikou city,
    Hainan, P.R.China
    Tel: + 86 898 6854 0310
    Fax: + 86 898 6854 0119 null,nullChina
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59227-89-3 Laurocapram

  • China Shanghai chemrole co.,ltd [Manufacturers]
  • Tel: 021-50278900
  • Fax: 021-50278968
  • Address: No.6,bisheng road ,shanghai ,china null,ShanghaiChina
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59227-89-3 Laurocapram

  • Hong kong ADVANCED TECH. & IND. CO., LTD. [Distributor/Wholesaler]
  • Tel: 86-23902293
  • Fax: 86-27898314
  • Address: UNIT B, 1/F, CHEONG SHING IND. BLDG., 17 WALNUT ST., TAI KOK TSUI, KLN, HONG KONG Hong Kong,nilHong kong
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59227-89-3 LAUROCAPRAM (AZONE)

  • United States NetQem, LLC [Manufacturer]
  • Tel: (919) 544-4122
  • Fax: (919) 544-4109
  • Address: NetQem, LLC
    P.O. Box 12091
    Research Triangle Park
    NC 27709, USA null,nullUnited States
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59227-89-3 LAUROCAPRAM

  • China HANGZHOU THINK CHEMICAL CO. [Manufacturer]
  • Tel: +86-571-81956191/ +86-571-81956192
  • Fax: +86-571-81956190
  • Address: 425 MOGAN HILL ROAD ,
    HANGZHOU, 310011 CHINA null,nullChina
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References of 1-dodecylazepan-2-one
Title: Laurocapram
CAS Registry Number: 59227-89-3
CAS Name: 1-Dodecylhexahydro-2H-azepin-2-one
Synonyms: 1-dodecylazacycloheptan-2-one; N-dodecyl-e-caprolactam
Manufacturers' Codes: N-0252
Trademarks: Azone (Nelson)
Molecular Formula: C18H35NO
Molecular Weight: 281.48
Percent Composition: C 76.81%, H 12.53%, N 4.98%, O 5.68%
Literature References: Caprolactam derivative used to enhance percutaneous absorption of physiologically active agents. Also exhibits intrinsic anti-inflammatory activity. Prepn: A. P. Swain et al., J. Org. Chem. 18, 1087 (1953). Improved synthesis: V. J. Rajadhyaksha et al., EP 95096; eidem, US 4422970 (both 1983 to Nelson). Use as skin penetrant: V. J. Rajadhyaksha, US 3989816; US 4405616 (1976, 1983 to Nelson). Anti-inflammatory activity: E. L. Nelson, US 4310525 (1982 to Nelson). Pharmacology: R. B. Stoughton, Arch. Dermatol. 118, 474 (1982). Comprehensive description: idem, Drug Dev. Ind. Pharm. 9, 725 (1983). Topical antiviral activity in vivo: M. F. Leonard et al., Chemotherapy (Basel) 33, 151 (1987).
Properties: Clear, colorless liquid, mp -7°. bp50m 160°. d 0.91; n 1.4701. Insol in water. Freely sol in most organic solvents. LD50 rats, mice (g/kg): 8 i.v., i.p. (Stoughton).
Melting point: mp -7°
Boiling point: bp50m 160°
Index of refraction: n 1.4701
Density: d 0.91
Toxicity data: LD50 rats, mice (g/kg): 8 i.v., i.p. (Stoughton)
Use: Pharmaceutic aid (excipient).