Home > Name List By 1 > 1-[3-(5, 6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-4-piperidin-1-ylpiperidine- 4-carboxamide

CAS No 5942-95-0 , 1-[3-(5,
6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-4-piperidin-1-ylpiperidine-
4-carboxamide

  • Name: 1-[3-(5,
    6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-4-piperidin-1-ylpiperidine-
    4-carboxamide
  • Synonyms: Carpipramina [INN-Spanish]; Bay b 4343 b;Carbadipimidine; Carpipraminum [INN-Latin];1-[3-(5,
    6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-4-piperidin-1-ylpiperidine-
    4-carboxamide; EINECS 227-700-0; Carpipramine [INN];
  • CAS Registry Number:
  • Flash Point: 339.1°C
  • Boiling Point: 637.1°C at 760 mmHg
  • Density: 1.143g/cm3
  • Refractive index: 1.598
  • Safety Statements: Poison by intraperitoneal and intravenous route. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of NOx.
  • Flash Point: 339.1°C
  • EINECS: 227-700-0
  • Molecular Weight: 446.62752
  • InchiKey: NWPJLRSCSQHPJV-UHFFFAOYSA-N
  • InChI: InChI=1S/C28H38N4O/c29-27(33)28(31-18-6-1-7-19-31)15-21-30(22-16-28)17-
    8-20-32-25-11-4-2-9-23(25)13-14-24-10-3-5-12-26(24)32/h2-5,9-12H,1,6-8,
    13-22H2,(H2,29,33)
  • Molecular Formula: C28H38N4O
  • Molecular Structure:CAS No:5942-95-0 1-[3-(5,<br />6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-4-piperidin-1-ylpiperidine-<br />4-carboxamide

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References of 1-[3-(5,
6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-4-piperidin-1-ylpiperidine-
4-carboxamide
Title: Carpipramine
CAS Registry Number: 5942-95-0
CAS Name: 1￠-[3-(10,11-Dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]-[1,4￠-bipiperidine]-4￠-carboxamide
Synonyms: 5-[3-(4-piperidino-4-carbamoylpiperidino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine; carbadipimidine
Manufacturers' Codes: Bay b 4343 b
Molecular Formula: C28H38N4O
Molecular Weight: 446.63
Percent Composition: C 75.30%, H 8.58%, N 12.54%, O 3.58%
Literature References: Prepn: M. Nakanishi, T. Munakata, JP 66 6752; GB 1017986; Nakanishi et al., US 3329683 (1966, 1966, 1967 all to Yoshitomi); Nakanishi et al., J. Med. Chem. 13, 644 (1970). Pharmacology: Nakanishi et al., Arzneim.-Forsch. 18, 1435 (1968). Metabolism: Nakanishi et al., J. Pharm. Soc. Jpn. 90, 204 (1970).
 
Derivative Type: Dihydrochloride monohydrate
CAS Registry Number: 7075-03-8
Trademarks: Defekton (Yoshitomi); Prazinil (Specia)
Molecular Formula: C28H38N4O.2HCl.H2O
Molecular Weight: 537.56
Percent Composition: C 62.56%, H 7.88%, N 10.42%, O 5.95%, Cl 13.19%
Properties: Crystals from 90% methanol, mp 260°. Sparingly sol in water. LD50 in mice, rats (mg/kg): 28.2, 37.0 i.v.; 136.0, 76.0 i.p.; 2180, 1025 orally (Nakanishi, 1968).
Melting point: mp 260°
Toxicity data: LD50 in mice, rats (mg/kg): 28.2, 37.0 i.v.; 136.0, 76.0 i.p.; 2180, 1025 orally (Nakanishi, 1968)
 
Therap-Cat: Antipsychotic.
Keywords: Antipsychotic; Other Tricyclics.