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CAS No 60-80-0 , 1,5-dimethyl-2-phenylpyrazol-3-one

  • Name: 1,5-dimethyl-2-phenylpyrazol-3-one
  • Synonyms: Auralgan;Phenazone; Apirelina;1,5-dimethyl-2-phenylpyrazol-3-one; Anodynine; Antipirin; Analgesine; Antipyrin; Anodynin; Phenazon;
  • CAS Registry Number:
  • Transport: UN 3249
  • Melting Point: 109-113 ºC
  • Flash Point: 109.4°C
  • Boiling Point: 319 ºC
  • Density: 1,19 g/cm3
  • Refractive index: 1.553
  • Water Solubility: 1000 G/L (20 ºC)
  • Safety Statements: R22;R36/37/38
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 109.4°C
  • EINECS: 200-486-6
  • Molecular Weight: 188.22578
  • InchiKey: VEQOALNAAJBPNY-UHFFFAOYSA-N
  • InChI: InChI=1S/C11H12N2O/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3
  • Risk Statements: S26;S37/39
  • Molecular Formula: C11H12N2O
  • Molecular Structure:CAS No:60-80-0 1,5-dimethyl-2-phenylpyrazol-3-one
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60-80-0 Antipyrine

  • Antipyrine Synonyms: 1,2-dihydro-1,5-dimethyl-2-phenyl-3h-pyrazol-3-on;1,5-Dimethyl1-2-phenyl-3-pyrazolone;1,5-Dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one;1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one;1-Pheny-1-2,3-dimethylpyrazolone-[5],1,2-Di-...
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  • China Hubei Yuancheng Saichuang Technology Co.,Ltd. [Manufacturer]
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  • Address: Wuchang wuhan,HubeiChina
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60-80-0 Antipyrine

  • Product Name: Antipyrine Synonyms: Antipyrene; 2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one; Phenazone; Antipyrine,(2,3-Dimethyl-1-phenyl-3-pyr; antipyrin(R); APYRETINE; Antipyrin; 1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one; 1,5-dimethyl-2-phenyl-...
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  • Address: No. 496 Zhongshan Road, Wuchang, Wuhan, Hubei Wuhan, Hubei,HubeiChina
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60-80-0 Antipyrine

  • Product Name: Antipyrine Synonyms: Antipyrene; 2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one; Phenazone; Antipyrine,(2,3-Dimethyl-1-phenyl-3-pyr; antipyrin(R); APYRETINE; Antipyrin; 1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one; 1,5-dimethyl-2-phenyl-...
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  • China Hubei Yuancheng Saichuang Technology Co.,Ltd [Manufacturer]
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60-80-0 Antipyrine

  • Product Name: Antipyrine Synonyms: Antipyrene; 2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one; Phenazone; Antipyrine,(2,3-Dimethyl-1-phenyl-3-pyr; antipyrin(R); APYRETINE; Antipyrin; 1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one; 1,5-dimethyl-2-phenyl-...
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  • China Hubei Yuancheng Saichuang Technology Co.,Ltd [Manufacturer]
  • Tel: 86-027-50755973
  • Address: No.496,Zhongshan Road,Wuchang District wuhan,HubeiChina
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60-80-0 Antipyrine

  • 1. Quick Detail: Product Name: Antipyrine Synonyms: Antipyrene; 2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one; Phenazone; Antipyrine,(2,3-Dimethyl-1-phenyl-3-pyr; antipyrin(R); APYRETINE; Antipyrin; 1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one; 1,5-d...
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  • China Wuhan Yuancheng Gongchuang Technology Co.,Ltd [Manufacturer]
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  • Fax: 86-027-68886696
  • Address: No. 496 Zhongshan Road, Wuchang Wuhan,HebeiChina
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60-80-0 Antipyrine

  • United States HBCChem, Inc. [Manufacturers]
  • Tel: +1-510-219-6317
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  • Address: null Union City,CaliforniaUnited States
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60-80-0 4-Isopropylantipyrine

  • 4-Isopropylantipyrine
  • Hong kong Frapp's Pharma (Hongkong) Co.,Ltd [Manufacturer]
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  • Address: Room 801,Mongkok Harbour Centre,638 Shanghai Street,Mongkok,Kowloon,Hongkang518001 MongkokHONG KONG Mongkok,nullHong kong
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60-80-0 Propy phenazon

  • Propy phenazonPropy phenazon, 98%
  • China PMIDA AGROCHEMICAL CO.,LTD [Manufacturer]
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  • Address: 17F,Venus Science Incubate Center,No.60 Xingguang Road,New North Zone401121 ChongqingCHINA Chongqing,nullChina
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60-80-0 Propy phenazon

  • Propy phenazon, 98%
  • China Shanghai Rainbow Chemistry Co., Ltd. [Manufacturer]
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  • Address: Room 128, Building B, No. 8 Lane 1305, Huajing Road, Xuhui District, Shanghai, P.R. China 200000 Shanghai CHINA Shanghai,nullChina
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60-80-0 Budesonide

  • Budesonide
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
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References of 1,5-dimethyl-2-phenylpyrazol-3-one
Title: Antipyrine
CAS Registry Number: 60-80-0
CAS Name: 1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one
Synonyms: 2,3-dimethyl-1-phenyl-3-pyrazolin-5-one; phenazone; 1,5-dimethyl-2-phenyl-3-pyrazolone; phenyldimethylpyrazolon(e); dimethyloxychinizin; dimethyloxyquinazine; oxydimethylquinizine
Trademarks: Analgesine; Anodynine; Parodyne; Phenylone; Sedatine
Molecular Formula: C11H12N2O
Molecular Weight: 188.23
Percent Composition: C 70.19%, H 6.43%, N 14.88%, O 8.50%
Literature References: Prepn: Müller et al., Monatsh. Chem. 89, 23 (1958); Hagers Handb. Pharm. Praxis Vol. 6 (Springer Verlag, Berlin, 1977) p 571. Toxicity: Hart, J. Pharmacol. Exp. Ther. 89, 205 (1947). Metabolism: H. Uchino et al., Xenobiotica 13, 155 (1983). Clinical comparison with paracetamol: H. Quiding et al., Int. J. Oral Surg. 11, 304 (1982). Use as indicator of hepatic drug metabolism: E. S. Vessel, Clin. Pharm. Ther. 26, 275 (1979); G. C. Farrell, L. Zaluzny, Br. J. Clin. Pharmacol. 18, 559 (1984). HPLC determn in urine: E. Brendel et al., J. Pharm. Biomed. Anal. 7, 1783 (1989). Clinical pharmacokinetics: H. A. Ali et al., Hum. Exp. Toxicol. 13, 658 (1994).
Properties: Tabular crystals or white powder; slightly bitter taste. mp 111-113°. One gram dissolves in less than 1 ml water, 1.3 ml alcohol, 1 ml chloroform, 43 ml ether. The aq soln is neutral to litmus. LD50 orally in rats: 1.8 g/kg (Hart).
Melting point: mp 111-113°
Toxicity data: LD50 orally in rats: 1.8 g/kg (Hart)
 
Derivative Type: Acetylsalicylate
CAS Registry Number: 569-84-6
Trademarks: Acetopyrine; Acopyrine; Acetasol
Molecular Formula: C20H20N2O5
Molecular Weight: 368.38
Percent Composition: C 65.21%, H 5.47%, N 7.60%, O 21.72%
Properties: Crystals, mp 63-65°. One part dissolves in 400 parts of water, in 20 parts of 2% aq sod. bicarbonate soln. Freely sol in hot water, cold alc, chloroform; sparingly sol in ether. Note: Not to be confused with antipyrine salicylacetate.
Melting point: mp 63-65°
 
Derivative Type: Mandelate
CAS Registry Number: 603-64-5
Synonyms: Antipyrine amygdalate
Molecular Formula: C11H12N2O.C8H8O3
Molecular Weight: 340.37
Percent Composition: C 67.05%, H 5.92%, N 8.23%, O 18.80%
Properties: Cryst powder, mp 52-55°. One gram dissolves in 15 ml water, 4 ml alc, 26 ml ether.
Melting point: mp 52-55°
 
Derivative Type: Methylethylglycolate
CAS Registry Number: 5794-16-1
Synonyms: Antipyrine 2-hydroxy-2-methylbutyrate
Trademarks: Astrolin
Molecular Formula: C16H22N2O4
Molecular Weight: 306.36
Percent Composition: C 62.73%, H 7.24%, N 9.14%, O 20.89%
Properties: Crystalline powder, mp 64-65.5°. Soluble in water, alc.
Melting point: mp 64-65.5°
 
Derivative Type: Salicylacetate
CAS Registry Number: 603-59-8
Synonyms: a-Carboxy-o-anisic acid compd with antipyrine
Trademarks: Pyrosal
Molecular Formula: C20H20N2O6
Molecular Weight: 384.38
Percent Composition: C 62.49%, H 5.24%, N 7.29%, O 24.97%
Properties: Crystals, mp 149-150°. Bitter, acid taste. Sparingly soluble in water; soluble in alc. Note: Not to be confused with antipyrine acetylsalicylate.
Melting point: mp 149-150°
 
Therap-Cat: Analgesic.
Therap-Cat-Vet: Has been used as an antipyretic, analgesic and in laminitis of horses.
Keywords: Analgesic (Non-Narcotic).