Home > Name List By 3 > 3-[3-(4-benzhydrylpiperazin-1-yl)propyl]-1H-benzimidazol-2-one

CAS No 60607-34-3 , 3-[3-(4-benzhydrylpiperazin-1-yl)propyl]-1H-benzimidazol-2-one

  • Name: 3-[3-(4-benzhydrylpiperazin-1-yl)propyl]-1H-benzimidazol-2-one
  • Synonyms: Oxatomida; Celtect; Oxatomidum [INN-Latin]; Oxatomidum; Oxetal; Oxatimide;Tinset; KW-4354; 60607-34-3;3-[3-(4-benzhydrylpiperazin-1-yl)propyl]-1H-benzimidazol-2-one;
  • CAS Registry Number:
  • Melting Point: 153.60C
  • Density: 1.175 g/cm3
  • Refractive index: 1.619
  • Water Solubility: DMSO: soluble
  • Safety Statements: R22
  • Hazard Symbols: Xn: Harmful;
  • EINECS: 262-320-9
  • Molecular Weight: 426.5533
  • InchiKey: BAINIUMDFURPJM-UHFFFAOYSA-N
  • InChI: InChI=1S/C27H30N4O/c32-27-28-24-14-7-8-15-25(24)31(27)17-9-16-29-18-20-
    30(21-19-29)26(22-10-3-1-4-11-22)23-12-5-2-6-13-23/h1-8,10-15,26H,9,
    16-21H2,(H,28,32)
  • Risk Statements: R22
  • Molecular Formula: C27H30N4O
  • Molecular Structure:CAS No:60607-34-3 3-[3-(4-benzhydrylpiperazin-1-yl)propyl]-1H-benzimidazol-2-one
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60607-34-3 OXATOMIDE

  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany ,Germany
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60607-34-3 Oxatomide

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 ,United States
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60607-34-3 2H-Benzimidazol-2-one,1-[3-[4-(diphenylmethyl)-1-piperazinyl]propyl]-1,3-dihydro-

  • China Boronsyn Co.,Ltd [Manufacturer]
  • Tel: +86-21-58407925
  • Fax: +86-21-58408291
  • Address: 1213 JunMin Road,Pudong,China ,China
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60607-34-3 Oxatomide

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60607-34-3 2H-Benzimidazol-2-one,1-[3-[4-(diphenylmethyl)-1-piperazinyl]propyl]-1,3-dihydro-

  • China KINFON PHARMACEUTICAL AND CHEMICAL CO.LTD [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: +86-23-8650081
  • Fax: +86-23-8650081
  • Address: 7F,Commercial Building, No.3 Nanping West Road,Nan ,China
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60607-34-3 Oxatomide

  • Hong kong LEO CHEMICAL (HONG KONG) CO., LTD [Manufacturer]
  • Tel: 86-519-85098858/ 86-519-85098877
  • Fax: 86-519-85098888/8889
  • Address: Hong Kong Office :
    LEO CHEMICAL (HONG KONG) CO., LTD
    MNJ2070, RM1602,
    OMEGA PLAZA, 32 DUNDAS STREET,
    MONKOK, KL, HONG KONG ,Hong kong
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60607-34-3 OXATOMIDE

  • Canada Synth?se AptoChem Inc. [Manufacturer]
  • Tel: 514-496-4252
  • Fax: 514-496-4253
  • Address: Synth?se AptoChem Inc.
    6100 Royalmount Ave
    Montreal, QC
    Canada
    H4P 2R2 ,Canada
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60607-34-3 2H-Benzimidazol-2-one,1-[3-[4-(diphenylmethyl)-1-piperazinyl]propyl]-1,3-dihydro-

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60607-34-3 OXATOMIDE

  • China FAITH EAGLE (LABORATORY) LTD. [Manufacturers]
  • Tel: (+86-755) 82851290
  • Fax: +86-755-83164680 83662918
  • Address: 15A/F.,Block A,World Trade Plaza,8# FuHong Rd., FuTian,Shenzhen, China Shenzhen,GuangdongChina
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60607-34-3 Oxatomide

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References of 3-[3-(4-benzhydrylpiperazin-1-yl)propyl]-1H-benzimidazol-2-one
Title: Oxatomide
CAS Registry Number: 60607-34-3
CAS Name: 1-[3-[4-(Diphenylmethyl)-1-piperazinyl]propyl]-1,3-dihydro-2H-benzimidazol-2-one
Synonyms: 1-[3-[4-(diphenylmethyl)-1-piperazinyl]propyl]-2-benzimidazolinone
Manufacturers' Codes: R-35443
Trademarks: Celtect (Kyowa); Cobiona (Esteve); Dasten (Duncan); Tinset (Janssen)
Molecular Formula: C27H30N4O
Molecular Weight: 426.55
Percent Composition: C 76.03%, H 7.09%, N 13.13%, O 3.75%
Literature References: Orally active anti-allergic agent, related structurally to cinnarizine, q.v., and having a novel biphasic mode of action. Prepn: J. Vandenberk et al., DE 2714437; eidem, US 4250176 (1977, 1981 both to Janssen). Inhibition of release and effects of allergic mediators: F. Awouters et al., Experientia 33, 1657 (1977). In vitro study of inhibition and stimulation of histamine release: M. K. Church et al., Agents Actions 10, 4 (1980). In vivo study: S. Gatti et al., Br. J. Dermatol. 103, 671 (1980). Clinical studies: S. W. Barham, F. Moran, Br. J. Clin. Pract. 34, 323 (1980); E. F. Juniper et al., Clin. Allergy 11, 61 (1981); W. Peremans et al., Dermatologia 162, 42 (1981). Review of pharmacological and clinical studies: D. M. Richards et al., Drugs 27, 210 (1984).
Properties: White powder, mp 153.6°. LD50 in guinea pigs, mice, rats (mg/kg): 320, >2560, >2560 orally; 23, 27, 30 i.v. (Richards).
Melting point: mp 153.6°
Toxicity data: LD50 in guinea pigs, mice, rats (mg/kg): 320, >2560, >2560 orally; 23, 27, 30 i.v. (Richards)
Therap-Cat: Antiallergic; antiasthmatic.
Keywords: Antiallergic; Antiasthmatic (Nonbronchodilator).