Home > Name List By 4 > 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[(2R)-2-[[(4-hydroxy-1,5-naphthyridin-3-yl)carbonyl]amino]-2-phenylacet...

CAS No 63469-19-2 , 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[(2R)-2-[[(4-hydroxy-1,5-naphthyridin-3-yl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-,(2S,5R,6R)-

  • Name: 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[(2R)-2-[[(4-hydroxy-1,5-naphthyridin-3-yl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-,(2S,5R,6R)-
  • Synonyms: Apalcillin;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[(2R)-[[(4-hydroxy-1,5-naphthyridin-3-yl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-,(2S,5R,6R)- (9CI); 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[[[(4-hydroxy-1,5-naphthyridin-3-yl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-,[2S-[2a,5a,6b(S*)]]-; 1,5-Naphthyridine, 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid deriv.;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[(2R)-2-[[(4-hydroxy-1,5-naphthyridin-3-yl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-,(2S,5R,6R)-;
  • CAS Registry Number:
  • Flash Point: 513.5°C
  • Boiling Point: 925.4°C at 760 mmHg
  • Density: 1.55g/cm3
  • Refractive index: 1.723
  • Flash Point: 513.5°C
  • EINECS: 261-446-1
  • Molecular Weight: 521.5466
  • InChI: InChI=1/C25H23N5O6S/c1-25(2)19(24(35)36)30-22(34)17(23(30)37-25)29-21(33)15(12-7-4-3-5-8-12)28-20(32)13-11-27-14-9-6-10-26-16(14)18(13)31/h3-11,15,17,19,23H,1-2H3,(H,27,31)(H,28,32)(H,29,33)(H,35,36)/t15-,17-,19+,23-/m1/s1
  • Molecular Formula: C25H23 N5 O6 S
  • Molecular Structure:CAS No:63469-19-2 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[(2R)-2-[[(4-hydroxy-1,5-naphthyridin-3-yl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-,(2S,5R,6R)-

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63469-19-2 Apalcillin

  • Apalcillin, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
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63469-19-2 APALCILLIN

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
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  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[(2R)-2-[[(4-hydroxy-1,5-naphthyridin-3-yl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-,(2S,5R,6R)-
Title: Apalcillin
CAS Registry Number: 63469-19-2
CAS Name: (2S,5R,6R)-6-[[(2R)-[[(4-Hydroxy-1,5-naphthyridin-3-yl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Molecular Formula: C25H23N5O6S
Molecular Weight: 521.55
Percent Composition: C 57.57%, H 4.44%, N 13.43%, O 18.41%, S 6.15%
Literature References: Semi-synthetic antibiotic related to penicillin. Prepn of the potassium salt: H. Tobiki et al., ZA 7205865; eidem, US 3864329 (1973, 1975 both to Sumitomo); of the sodium salt: Y. Hirotada et al., US 4005075 (1977 to Sumitomo); H. Tobiki et al., Yakugaku Zasshi 100, 49 (1980), C.A. 93, 95179x (1980). Microbiological evaluation: H. Noguchi et al., Antimicrob. Agents Chemother. 9, 262 (1976). Analytical studies: I. Umeda et al., Yakugaku Zasshi 99, 717 (1979), C.A. 92, 11287z (1980). Series of articles on pharmacology, exptl and clinical effects: Chemotherapy (Tokyo) 26, Suppl. 2, 111-223 (1978). Pharmacokinetics in man: U. Busch et al., Arzneim.-Forsch. 32, 1131 (1982).
 
Derivative Type: Sodium salt
CAS Registry Number: 58795-03-2
Manufacturers' Codes: PC-904
Trademarks: Lumota (Thomae)
Molecular Formula: C25H22N5NaO6S
Molecular Weight: 543.53
Percent Composition: C 55.24%, H 4.08%, N 12.88%, Na 4.23%, O 17.66%, S 5.90%
Properties: White cryst, sol in water.
 
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); ?Lactams; Penicillins.