Home > Name List By 2 > 2-[5-(3-methylbut-2-enoxy)-2-[(E)-3-[4-(3-methylbut-2-enoxy)phenyl]prop- 2-enoyl]phenoxy]acetic acid

CAS No 64506-49-6 , 2-[5-(3-methylbut-2-enoxy)-2-[(E)-3-[4-(3-methylbut-2-enoxy)phenyl]prop-
2-enoyl]phenoxy]acetic acid

  • Name: 2-[5-(3-methylbut-2-enoxy)-2-[(E)-3-[4-(3-methylbut-2-enoxy)phenyl]prop-
    2-enoyl]phenoxy]acetic acid
  • Synonyms: BRN 2191482; Sofalcona [Spanish]; SU-88;2-[5-(3-methylbut-2-enoxy)-2-[(E)-3-[4-(3-methylbut-2-enoxy)phenyl]prop-
    2-enoyl]phenoxy]acetic acid; Isoprenyl chalcone; 64506-49-6;Solon; SU 88; Sofalconum [Latin];
  • CAS Registry Number:
  • Density: 1.149 g/cm
  • Refractive index: 1.578
  • Molecular Weight: 450.5235
  • InchiKey: GFWRVVCDTLRWPK-KPKJPENVSA-N
  • InChI: InChI=1S/C27H30O6/c1-19(2)13-15-31-22-8-5-21(6-9-22)7-12-25(28)24-11-10-
    23(32-16-14-20(3)4)17-26(24)33-18-27(29)30/h5-14,17H,15-16,18H2,1-4H3,
    (H,29,30)/b12-7+
  • Molecular Formula: C27H30O6
  • Molecular Structure:CAS No:64506-49-6 2-[5-(3-methylbut-2-enoxy)-2-[(E)-3-[4-(3-methylbut-2-enoxy)phenyl]prop-<br />2-enoyl]phenoxy]acetic acid
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64506-49-6 sofalcone

  • China Hangzhou Sage Chemical Co., Ltd. [Manufacturer]
  • Tel: +86-571-86818502
  • Fax: +86-571-86818503
  • Address: RM501 Tower A, New Youth Plaza, NO.8 Jia Shan Road, Hangzhou, Zhejiang 310014, null,ZhejiangChina
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64506-49-6 sofalcone

  • China XinChem Corporation [Manufacturers]
  • Tel: +86-(21)-34123252
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  • Address: 102/30, 3455 Chunshen Road, Shanghai 201100, null,ShanghaiChina
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  • China Kouting Chemical Co.,Ltd [Importer/Exporter]
  • Tel: +86-(21)-58116473
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  • Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318, shanghai,shanghaiChina
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64506-49-6 sofalcone

  • United States Waterstone Technology LLC [Manufacturer]
  • Tel: 317-644-0862/ 317-218-7464
  • Fax: 317-569-8068
  • Address: Waterstone Technology LLC
    12202 Hancock Street
    Carmel, IN. 46032 null,nullUnited States
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64506-49-6 SOFALCONE

  • China HANGZHOU THINK CHEMICAL CO. [Manufacturer]
  • Tel: +86-571-81956191/ +86-571-81956192
  • Fax: +86-571-81956190
  • Address: 425 MOGAN HILL ROAD ,
    HANGZHOU, 310011 CHINA null,nullChina
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  • China Xingcheng Chempharm Co., Ltd [Manufacturer]
  • Tel: +86-576-88525005/ +86-576-88886292
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  • Address: B Area, 10F, Yaoda Mansion, 289, Shifu Road, Taizhou, Zhejiang, China 318000 null,nullChina
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  • China Taizhou Crene Chempharm Co., Ltd. null
  • Tel: +86-(576)-88813233
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  • Address: Weiwu Load Economic Developed Zone, Taizhou, Zhejiang 318000, null,nullChina
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  • China Chemfar Ltd. null
  • Fax: 86-571-87859289
  • Address: 16E,Huarong Times Mansion, No.3880 Jiangnan Avenue, Binjiang District, Hangzhou, China null,nullChina
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References of 2-[5-(3-methylbut-2-enoxy)-2-[(E)-3-[4-(3-methylbut-2-enoxy)phenyl]prop-
2-enoyl]phenoxy]acetic acid
Title: Sofalcone
CAS Registry Number: 64506-49-6
CAS Name: [5-[(3-Methyl-2-butenyl)oxy]-2-[3-[4-[(3-methyl-2-butenyl)oxy]phenyl]-1-oxo-2-propenyl]phenoxy]acetic acid
Synonyms: 2¢-carboxymethoxy-4,4¢-bis(3-methyl-2-butenyloxy)chalcone
Manufacturers' Codes: Su-88
Trademarks: Solon (Taisho)
Molecular Formula: C27H30O6
Molecular Weight: 450.52
Percent Composition: C 71.98%, H 6.71%, O 21.31%
Literature References: Substituted chalcone with anti-ulcer activity. Prepn: K. Kyogoku et al., DE 2705603; eidem, US 4085135 (1977, 1978 both to Taisho); eidem, Chem. Pharm. Bull. 27, 2943 (1979). Effects on exptl ulcer models: R. Saziki et al., Oyo Yakuri 18, 579 (1979), C.A. 92, 174433h (1980). Absorption, distribution, excretion: T. Nozu et al., ibid. 815, C.A. 92, 191017t (1980). Reproduction studies: T. Yamada et al., ibid. 19, 543 (1980), C.A. 93, 230785j (1980). Toxicity study: Y. Tarumoto et al., Yakuri to Chiryo 10, 61 (1982), C.A. 96, 193205j (1982). Effect on gastric blood flow: Y. Matsuo et al., Arzneim.-Forsch. 33, 242 (1983). Gastric cytoprotective effect in rats: T. Suwa et al., Jpn. J. Pharmacol. 35, 47 (1984); S. Kishimoto et al., Arzneim.-Forsch. 31, 944 (1987).
Properties: Light yellow needles from ethanol, mp 143-144°. LD50 in mice, rats: >10 g/kg orally (Tarumoto).
Melting point: mp 143-144°
Toxicity data: LD50 in mice, rats: >10 g/kg orally (Tarumoto)
Therap-Cat: Antiulcerative.
Keywords: Antiulcerative; Cytoprotectant (Gastric).