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CAS No 738-70-5 , 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine

  • Name: 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
  • Synonyms: 738-70-5; Trimpex; Sulfamethoprim; Trimopan; Monotrim; Syraprim; Monotrimin;Proloprim; Bactramin;5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine;
  • CAS Registry Number:
  • Transport: 3249
  • Melting Point: 199-203 ºC
  • Flash Point: 271.9 ºC
  • Boiling Point: 526 ºC at 760 mmHg
  • Density: 1.252 g/cm3
  • Water Solubility: <0.1 G/100 ML AT 24 ºC
  • Safety Statements: S45
  • Hazard Symbols: T: Toxic;
  • Flash Point: 271.9 ºC
  • EINECS: 212-006-2
  • Molecular Weight: 290.31772
  • InchiKey: IEDVJHCEMCRBQM-UHFFFAOYSA-N
  • InChI: InChI=1S/C14H18N4O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-
    13(9)15/h5-7H,4H2,1-3H3,(H4,15,16,17,18)
  • Risk Statements: R25
  • Molecular Formula: C14H18N4O3
  • Molecular Structure:CAS No:738-70-5 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
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738-70-5 Trimethoprim

  • Product Name: Trimethoprim Synonyms: abaprim;5-((3,4,5-trimethoxyphenyl)methyl)-2,4-pyrimidinediamine;5-(3,4,5-trimethoxybenzyl)-2,4-diaminopyrimidine;5-(3,4,5-TRIMETHOXYBENZYL)PYRIMIDINE-2,4-DIYLAMINE;2,4-DIAMINO-5-(3,4,5-TRIMETHOXYBENZYL)PYRIMIDE;2...
  • Min. Order: 500
  • FOB Price: USDfalse - false /
  • China Wuhan Hezhong Bio-Chemical Manufature Co.,Ltd [Manufacturer]
  • Tel: 86-27-50756046
  • Address: Zhongshan Road No 496 Wuhan,HubeiChina
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738-70-5 Trimethoprim

  • Product Name: Trimethoprim Synonyms: abaprim;5-((3,4,5-trimethoxyphenyl)methyl)-2,4-pyrimidinediamine;5-(3,4,5-trimethoxybenzyl)-2,4-diaminopyrimidine;5-(3,4,5-TRIMETHOXYBENZYL)PYRIMIDINE-2,4-DIYLAMINE;2,4-DIAMINO-5-(3,4,5-TRIMETHOXYBENZYL)PYRIMIDE;2...
  • Min. Order: 500
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  • China Wuhan Yuancheng Gongchuang Technology Co.Ltd. [Manufacturer]
  • Tel: 86-27-50756064
  • Address: No.496,Zhongshan Road, Wuhan, Hubei, China Wuhan,HubeiChina
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738-70-5 Trimethoprim

  • "Appearance White or yellowish-white powder Solubility Very slightly soluble in water, slightly soluble in alcohol. ?Identification A: Melting point B: Specific absorbance C: IR-spectrum D: Chemical reaction 199-203℃ Max.287nm: 240-250 Complies with...
  • China Hangzhou Dingyan Chem Co.,Ltd [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: 86-571-88025800
  • Fax: 86-571-87156470
  • Address: Xiasha 571, 19TH Street E-COMMERCE 4A 601-602 , Jianggan Area hangzhou,ZhejiangChina

738-70-5 TRIMETHOPRIM

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  • China HongKong Yuancheng Tech Co.Ltd. [Manufacturer]
  • Tel: 86-027-50756063
  • Address: Flat C 4/F Civic Comm Bldg, 165-167 Woosung St Kln, Hong Kong,China
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738-70-5 Cotrimoxazole

  • China Chemrio International Limited [Manufacturer]
  • Tel: +86 574 2789 1268/ +86-139 5789 5864 (mobile)
  • Fax: +86 574 2789 1266
  • Address: Chemrio International Limited
    Room 611-612, Wante Business Center
    No.487 Yangmuqi Road,
    Hi-tech Park Ningbo, 315040,China ,China
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738-70-5 trimethoprim

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738-70-5 trimethoprim

  • United States HBCChem, Inc. [Manufacturers]
  • Tel: +1-510-219-6317
  • Fax: +1-510-675-0318
  • Address: Union City,CaliforniaUnited States
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738-70-5 Cotrimoxazole

  • China Trust&We Co., Ltd. [Manufacturer]
  • Tel: +86-21-61044582
  • Fax: +86-21-61044583
  • Address: 1-102,No.11,Dongjiaominxiang Alley,
    Dongcheng District,
    Beijing 100005,China ,China
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738-70-5 trimethoprim

  • China ORCHID CHEMICAL SUPPLIES LTD (OCS) [Importer/Exporter]
  • Tel: +86-571-85395792
  • Fax: +86-571-85420103
  • Address: 607, North Zhongshan Road, Hangzhou 310000 China ,ZhejiangChina
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738-70-5 Cotrimoxazole

  • China Shanghai Xunxin Chemical Co., Ltd [Manufacturers]
  • Tel: +86-(21)-38218795
  • Fax: +86-(21)-38218795
  • Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315, Shanghai,ShanghaiChina
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References of 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
Title: Trimethoprim
CAS Registry Number: 738-70-5
CAS Name: 5-[(3,4,5-Trimethoxyphenyl)methyl]-2,4-pyrimidinediamine
Synonyms: 2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine
Trademarks: Instalac (Virbac); Monotrim (Duphar); Proloprim (Wellcome); Syraprim (Wellcome); Tiempe (DDSA); Trimanyl (Tosse); Trimogal (Lagap); Trimopan (Berk); Trimpex (Roche); Uretrim (Bastian); Wellcoprim (Wellcome)
Molecular Formula: C14H18N4O3
Molecular Weight: 290.32
Percent Composition: C 57.92%, H 6.25%, N 19.30%, O 16.53%
Literature References: Prepn from guanidine and b-ethoxy-3,4,5-trimethoxybenzylbenzalnitrile: Stenbuck, Hood, US 3049544 (1962 to Burroughs Wellcome); Hoffer, US 3341541 (1967 to Hoffmann-La Roche). Improved synthesis: B. Roth et al., J. Med. Chem. 23, 379, 535 (1980). Toxicity data: Yamamoto et al., Chemotherapy (Tokyo) 21, 187 (1973). Review: Burchall in Antibiotics vol. 3, J. W. Corcoran, F. E. Hahn, Eds. (Springer-Verlag, New York, 1975) pp 304-320. Comprehensive description: G. J. Manius, Anal. Profiles Drug Subs. 7, 445-475 (1978). Review of antibacterial activity, pharmacokinetics and therapeutic use: R. N. Brogden et al., Drugs 23, 405-430 (1982).
Properties: White to cream, bitter crystalline powder, mp 199-203°. Soly in g/100 ml at 25°: DMAC 13.86; benzyl alcohol 7.29; propylene glycol 2.57; chloroform 1.82; methanol 1.21; water 0.04; ether 0.003; benzene 0.002. pKa 6.6. LD50 orally in mice: 7000 mg/kg (Yamamoto).
Melting point: mp 199-203°
pKa: pKa 6.6
Toxicity data: LD50 orally in mice: 7000 mg/kg (Yamamoto)
NOTE: See Sulfamethoxazole, Sulfadiazine, Sulfametrole, Sulfamoxole, and Sulfalene for lists of trade names of mixtures with Trimethoprim.
Therap-Cat: Antibacterial.
Therap-Cat-Vet: Antibacterial.
Keywords: Antibacterial (Synthetic); 2,4-Diaminopyrimidines.