Home > Name List By c > Card-20(22)-enolide,3,11,14-trihydroxy-, (3b,5b,11a)-

CAS No 76-28-8 , Card-20(22)-enolide,3,11,14-trihydroxy-, (3b,5b,11a)-

  • Name: Card-20(22)-enolide,3,11,14-trihydroxy-, (3b,5b,11a)-
  • Synonyms: Sarmentogenin (6CI); 3b,11a,14-Trihydroxy-5b-card-20(22)-enolide;5b-Card-20(22)-enolide, 3b,11a,14-trihydroxy- (7CI,8CI);Card-20(22)-enolide,3,11,14-trihydroxy-, (3b,5b,11a)-; 11a-Hydroxydigitoxigenin;
  • CAS Registry Number:
  • Flash Point: 203°C
  • Boiling Point: 589.4°Cat760mmHg
  • Density: 1.297g/cm3
  • Refractive index: 1.609
  • Flash Point: 203°C
  • Molecular Weight: 390.5131
  • InChI: InChI=1/C23H34O5/c1-21-7-5-15(24)10-14(21)3-4-17-20(21)18(25)11-22(2)16(6-8-23(17,22)27)13-9-19(26)28-12-13/h9,14-18,20,24-25,27H,3-8,10-12H2,1-2H3/t14-,15+,16-,17-,18-,20-,21+,22-,23+/m1/s1
  • Molecular Formula: C23H34 O5
  • Molecular Structure:CAS No:76-28-8 Card-20(22)-enolide,3,11,14-trihydroxy-, (3b,5b,11a)-

Related products

Select to

76-28-8 Card-20(22)-enolide,3,11,14-trihydroxy-, (3b,5b,11a)-

Contact Supplier

Select to

1/1
References of Card-20(22)-enolide,3,11,14-trihydroxy-, (3b,5b,11a)-
Title: Sarmentogenin
CAS Registry Number: 76-28-8
CAS Name: (3b,5b,11a)-3,11,14-Trihydroxy-card-20(22)-enolide
Molecular Formula: C23H34O5
Molecular Weight: 390.51
Percent Composition: C 70.74%, H 8.78%, O 20.49%
Literature References: An aglucon from sarmentocymarin isolated from the seeds of Strophanthus sarmentosus DC. var. senegambiae (A. DC.) Monachino, Apocynaceae: Jacobs, Heidelberger, J. Biol. Chem. 81, 765 (1929); Katz, Helv. Chim. Acta 31, 993 (1948). Structure: Callow, Taylor, J. Chem. Soc. 1952, 2299; Repke, Klesczewski, Arch. Exp. Pathol. Pharmakol. 239, 131 (1960).
Properties: Prisms from methanol or methanol + acetone, mp 278-282°. [a]D19 +21.1 ± 4° (c = 0.521 in methanol). Absorption max (98% H2SO4): 230, 415 nm (E1%1cm 460, 430). Sol in alcohol, methanol, pyridine; sparingly sol in acetone, chloroform; practically insol in benzene, ether. Dissolves in concd H2SO4 with a bright golden color which slowly turns green and then indigo. In dil pyridine soln gives a deep red color with alkaline nitroprusside soln. When recrystallized from pyridine, it forms long microplatelets contg ~1 mol of the solvent and melting at 258° with effervescence. Is not precipitated with digitonin. Yields sarmentogenone on oxidation.
Melting point: mp 278-282°; melting at 258°
Optical Rotation: [a]D19 +21.1 ± 4° (c = 0.521 in methanol)
Absorption maximum: Absorption max (98% H2SO4): 230, 415 nm (E1%1cm 460, 430)
 
Derivative Type: Diacetate
Molecular Formula: C27H38O7
Molecular Weight: 474.59
Percent Composition: C 68.33%, H 8.07%, O 23.60%
Properties: Needles from abs ether, mp 135-155°. Not affected by CrO3 in acetic acid.
Melting point: mp 135-155°
 
Derivative Type: Dibenzoate
Molecular Formula: C37H42O7
Molecular Weight: 598.73
Percent Composition: C 74.22%, H 7.07%, O 18.71%
Properties: Flat hexagonal prisms from acetone, mp 281°. [a]D20 +14° (acetone). Sparingly sol in alc; practically insol in ether. Not affected by CrO3 in acetic acid.
Melting point: mp 281°
Optical Rotation: [a]D20 +14° (acetone)
 
 
Status: This monograph has been retired and is no longer subject to revision or update.