References of (8S,9R,10S,11S,13S,14S,17S)-9-fluoro-11,17-dihydroxy-10,13,
17-trimethyl-1,2,6,7,8,11,12,14,15,
16-decahydrocyclopenta[a]phenanthren-3-one
Title: Fluoxymesterone
CAS Registry Number: 76-43-7
CAS Name: (11b,17b)-9-Fluoro-11,17-dihydroxy-17-methylandrost-4-en-3-one
Synonyms: 11b,17b-dihydroxy-9a-fluoro-17a-methyl-4-androsten-3-one; 9a-fluoro-11b-hydroxy-17a-methyltestosterone
Trademarks: Halotestin (Pfizer)
Molecular Formula: C20H29FO3
Molecular Weight: 336.44
Percent Composition: C 71.40%, H 8.69%, F 5.65%, O 14.27%
Literature References: Prepn: Herr
et al., J. Am. Chem. Soc. 78, 501 (1956).
cf. Herr,
US 2813881 (1957 to Upjohn). Comprehensive description: J. Kirschbaum,
Anal. Profiles Drug Subs. 7, 251-275 (1978).
Properties: Crystals, dec 270°. [a]D +109° (ethanol). uv max (ethanol): 240 nm (e 16700). Sol in pyridine; slightly sol in acetone, chloroform; sparingly sol in methanol. Practically insol in water, ether, benzene, hexanes.
Optical Rotation: [a]D +109° (ethanol)
Absorption maximum: uv max (ethanol): 240 nm (e 16700)
NOTE: This is a controlled substance (anabolic steroid):
21 CFR, 1308.13, as defined in 1300.01.
Therap-Cat: Androgen.
Keywords: Androgen.
![CAS No:76-43-7 (8S,9R,10S,11S,13S,14S,17S)-9-fluoro-11,17-dihydroxy-10,13,<br />17-trimethyl-1,2,6,7,8,11,12,14,15,<br />16-decahydrocyclopenta[a]phenanthren-3-one](/structure/cas-76/76-43-7.png)
