Home > Name List By a > Aztreonam

CAS No 78110-38-0 , Aztreonam

  • Name: Aztreonam
  • Synonyms: Aztreonam;[2s-[2a,3b(z)]]-2-[[[1-(2-amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid;
  • CAS Registry Number:
  • Density: 1.83
  • Safety Statements: S22;S24/25
  • Hazard Symbols: Xn
  • EINECS: 278-839-9
  • Molecular Weight: 435.43
  • InChI: InChI=1/C13H17N5O8S2/c1-5-7(10(20)18(5)28(23,24)25)16-9(19)8(6-4-27-12(14)15-6)17-26-13(2,3)11(21)22/h4-5,7H,1-3H3,(H2,14,15)(H,16,19)(H,21,22)(H,23,24,25)/b17-8-/t5-,7-/m0/s1
  • Risk Statements: S22,S24/25,
  • Molecular Formula: C13H17N5O8S2
  • Molecular Structure:CAS No:78110-38-0 Aztreonam

Related products

Search by region :

Select to

78110-38-0 AZTREONAM

  • China IFFECT CHEMPHAR CO., LTD. null
  • Tel: 0086 755-83761619 83760606
  • Fax: +86-25- 84270111
  • Address: 15A,Changfa Center, Building B ,No. 300,East Zhongshan Road,Baixia District,Nanjing,210002, P.R.China. Nanjing,JiangshuChina
Contact Supplier

78110-38-0 Aztreonam

  • China Byelen Chemicals Co., Ltd. [Manufacturers]
  • Tel: +86-(21)-5836-0125-, 5836-0126
  • Fax: +86-(21)-5836-0127
  • Address: Rm 804, Sino Life Tower,707 Zhangyang Road,Pudong New Area, Shanghai 200120, shanghai,shanghaiChina
Contact Supplier

78110-38-0 Aztreonam

  • China Kangrui BIO-TECH Co.,Ltd.(H.K.) [Manufacturers]
  • Tel: 0086-571-86680744
  • Fax: 0086-571-86680744
  • Address: 3-704, Xixi Fengshang, Wensan West Road, Hangzhou, Zhejiang, China Hangzhou,ZhejiangChina
Contact Supplier

78110-38-0 AZTREONAM

  • China FAITH EAGLE (LABORATORY) LTD. [Manufacturers]
  • Tel: (+86-755) 82851290
  • Fax: +86-755-83164680 83662918
  • Address: 15A/F.,Block A,World Trade Plaza,8# FuHong Rd., FuTian,Shenzhen, China Shenzhen,GuangdongChina
Contact Supplier

78110-38-0 Aztreonam

  • China EASYBUYER LTD., [Manufacturers]
  • Tel: +86-21-35015877 +86-13701868511
  • Fax: +86-21-35010877
  • Address: Room 407, Building 10, Hi-Shanghai Center, No.990 Dalian Rd,Shanghai 200092 China null,ShanghaiChina
Contact Supplier

78110-38-0 Aztreonam

  • China Inter-Chemical Ltd. [Manufacturers]
  • Tel: +86-(755)-82187211, 82192202
  • Fax: +86-(755)-82187212
  • Address: B-1108/1109, Tian An International Bldg., RenMin Nan Road, ShenZhen 518005, Shenzhen,GuangdongChina
Contact Supplier

78110-38-0 Aztreonam

  • Taiwan Sun Rise Chem. Ind. Co., Ltd. [Manufacturers]
  • Tel: 886 2 2502 8811
  • Fax: 886 2 2506 0050
  • Address: 4 Fl., No. 17, Sec. 3, Min Sheng E. RD, Taipei, Taiwan R.O.C. Taipei,nullTaiwan
Contact Supplier

78110-38-0 Aztreonam

Contact Supplier

78110-38-0 Aztreonam

Contact Supplier

78110-38-0 Aztreonam

  • China Beijing Mediking Biopharm Co., Ltd [Manufacturer]
  • Tel: +86-10-81769620/ +86-10-81769521
  • Fax: +86-10-81769652
  • Address: Hongxianghong Incubator, Beiqijia Town,
    Changping District
    Beijing China null,nullChina
Contact Supplier

Select to

9/16
Previous 5 6 7 8 9 10 11 12 13 14 Next
References of Aztreonam
Title: Aztreonam
CAS Registry Number: 78110-38-0
CAS Name: [2S-[2a,3b(Z)]]-2-[[[1-(2-Amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid
Synonyms: azthreonam
Manufacturers' Codes: SQ-26776
Trademarks: Azactam (BMS); Primbactam (Menarini)
Molecular Formula: C13H17N5O8S2
Molecular Weight: 435.43
Percent Composition: C 35.86%, H 3.94%, N 16.08%, O 29.40%, S 14.73%
Literature References: The first totally synthetic monocyclic b-lactam (monobactam) antibiotic. It has a high degree of resistance to b-lactamases and shows specific activity vs aerobic gram-negative rods. Prepn: R. B. Sykes et al., NL 8100571 (1981 to Squibb), C.A. 96, 181062x (1982). Fast-atom-bombardment mass spectra: A. I. Cohen et al., J. Pharm. Sci. 71, 1065 (1982). Activity vs gram-negative bacteria: R. B. Sykes et al., Antimicrob. Agents Chemother. 21, 85 (1982). Series of articles on structure-activity, in vitro and in vivo properties, pharmacokinetics: J. Antimicrob. Chemother. 8, Suppl. E, 1-148 (1981). Toxicology: G. R. Keim et al., ibid. 141. Mechanism of action study: A. D. Russell, J. R. Furr, ibid. 9, 329 (1982). Comparative stability to renal dipeptidase: H. Mikami et al., Antimicrob. Agents Chemother. 22, 693 (1982). Human pharmacokinetics: E. A. Swabb et al., ibid. 21, 944 (1982). Clinical evaluation in urinary tract infection: C. Donadio et al., Drugs Exp. Clin. Res. 13, 167 (1987). Clinical efficacy in neonatal sepsis: S. Sklavunu-Tsurutsoglu et al., Rev. Infect. Dis. 13, Suppl. 7, S591 (1991). Comprehensive description: K. Florey, Anal. Profiles Drug Subs. 17, 1-39 (1988).
Properties: White crystalline, odorless powder, dec 227°. Very slightly sol in ethanol, slightly sol in methanol, sol in DMF, DMSO. Practically insol in toluene, chloroform, ethyl acetate.
 
Derivative Type: Disodium salt
Molecular Formula: C13H15N5Na2O8S2
Molecular Weight: 479.40
Percent Composition: C 32.57%, H 3.15%, N 14.61%, Na 9.59%, O 26.70%, S 13.38%
Properties: LD50 (mg/kg): 3300 i.v. in mice; 6600 i.p. in rats (Keim).
Toxicity data: LD50 (mg/kg): 3300 i.v. in mice; 6600 i.p. in rats (Keim)
 
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); ?Lactams; Monobactams.