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CAS No 81846-19-7 , Remodulin

  • Name: Remodulin
  • Synonyms: [[(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-Hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl]oxy]acetic acid;Treprostinil;Remodulin;
  • CAS Registry Number:
  • Flash Point: 199.3°C
  • Boiling Point: 587.1°Cat760mmHg
  • Density: 1.158g/cm3
  • Refractive index: 1.553
  • Flash Point: 199.3°C
  • Molecular Weight: 390.51
  • InChI: InChI=1/C23H34O5/c1-2-3-4-7-17(24)9-10-18-19-11-15-6-5-8-22(28-14-23(26)27)20(15)12-16(19)13-21(18)25/h5-6,8,16-19,21,24-25H,2-4,7,9-14H2,1H3,(H,26,27)/t16-,17-,18+,19-,21+/m0/s1
  • Molecular Formula: C23H34O5
  • Molecular Structure:CAS No:81846-19-7 Remodulin
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81846-19-7 TREPROSTINIL

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
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81846-19-7 U-62,840

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81846-19-7 TREPROSTINIL

  • United States Cayman Chemical Company [Manufacturer]
  • Tel: 734-975-3939; 734-975-3897 (Sales)/ 800-364-9897 (Customer Service)
  • Address: 1180 E.Ellsworth Rd.
    Ann Arbor, MI 48197
    800-364-9897 null,nullUnited States
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81846-19-7 REMODULIN

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of Remodulin
Title: Treprostinil
CAS Registry Number: 81846-19-7
CAS Name: [[(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-Hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl]oxy]acetic acid
Synonyms: 9-deoxy-2￠,9a-methano-3-oxa-4,5,6-trinor-3,7-(1￠,3￠-interphenylene)-13,14-dihydroprostaglandin F1
Molecular Formula: C23H34O5
Molecular Weight: 390.51
Percent Composition: C 70.74%, H 8.78%, O 20.49%
Literature References: Synthetic analog of prostacyclin, q.v. Prepn: P. A. Aristoff et al., GB 2070596; idem, US 4306075 (both 1981 to Upjohn). Pharmacology: R. P. Steffen, M. de la Mata, Prostaglandins Leukotrienes Essen. Fatty Acids 43, 277 (1991). Pharmacokinetics: M. J. McNulty et al., ibid. 159; of intravenous and subcutaneous administration: K. Laliberte et al., J. Cardiovasc. Pharmacol. 44, 209 (2004). RIA determn in plasma: J. W. A. Findlay et al., ibid. 167. Clinical study in pulmonary arterial hypertension: G. Simonneau et al., Am. J. Respir. Crit. Care Med. 165, 800 (2002); by s. c. infusion: R. J. Oudiz et al., Chest 126, 420 (2004); by continuous i.v.: V. F. Tapson et al., ibid. 129, 683 (2006).
Properties: Crystals from ethyl acetate in hexane, mp 121-123°.
Melting point: mp 121-123°
 
Derivative Type: Sodium salt
CAS Registry Number: 289480-64-4
Manufacturers' Codes: 15AU81; BW15AU; U-62840; UT-15
Trademarks: Remodulin (United Ther.)
Molecular Formula: C23H33NaO5
Molecular Weight: 412.49
Percent Composition: C 66.97%, H 8.06%, Na 5.57%, O 19.39%
 
Therap-Cat: Antihypertensive.
Keywords: Antihypertensive.