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CAS No 82-95-1 , 1-[(4-tert-butylphenyl)methyl]-4-[(4-chlorophenyl)-phenylmethyl]
piperazine

  • Name: 1-[(4-tert-butylphenyl)methyl]-4-[(4-chlorophenyl)-phenylmethyl]
    piperazine
  • Synonyms: 1-[(4-tert-butylphenyl)methyl]-4-[(4-chlorophenyl)-phenylmethyl]
    piperazine; Buclodin; Histabutizine; Buclizinum [INN-Latin]; Bucladin; Aphilan-R base; Histabutyzine; Histabuticine;Vibazine; Buclifen;
  • CAS Registry Number:
  • Safety Statements: Experimental reproductive effects. When heated to decomposition it emits toxic vapors of NOx and Cl.
  • EINECS: 201-448-1
  • Molecular Weight: 433.02802
  • InchiKey: MOYGZHXDRJNJEP-UHFFFAOYSA-N
  • InChI: InChI=1S/C28H33ClN2/c1-28(2,
    3)25-13-9-22(10-14-25)21-30-17-19-31(20-18-30)27(23-7-5-4-6-8-23)24-11-
    15-26(29)16-12-24/h4-16,27H,17-21H2,1-3H3
  • Molecular Formula: C28H33ClN2
  • Molecular Structure:CAS No:82-95-1 1-[(4-tert-butylphenyl)methyl]-4-[(4-chlorophenyl)-phenylmethyl]<br />piperazine
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82-95-1 BUCLIZINE

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong ,Hong kong
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82-95-1 Oxyphenisatin

  • Oxyphenisatin, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
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  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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82-95-1 Buclizine

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82-95-1 Buclizine

  • India Manus Aktteva []
  • Tel: +91-(79)-65123395
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  • Address: 303, 3rd Floor, Royale Manor, Law Garden, Dhulia Kot Road, Ellisbridge, Ahmedabad, Gujarat 380006, ,India
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82-95-1 Buclizine, 99%

  • Buclizine, 99%
  • China Pleapharma Co.,Ltd [Manufacturer]
  • Tel: 86 23 67030808
  • Fax: 86 23 67030809
  • Address: 22F,Jingxin center,No.70 Xingguang Road,Yubei Zone,Chongqing402232 chongqingCHINA chongqing,China
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82-95-1 Buclizine

  • United States Parchem Trading [Manufacturer]
  • Tel: 914.654.6800
  • Fax: 914.654.6899
  • Address: Parchem Trading Ltd.
    415 Huguenot Street
    New Rochelle, NY 10801 ,United States
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82-95-1 BUCLIZINE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China ,China
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82-95-1 BUCLIZINE HCL

  • Canada Synth?se AptoChem Inc. [Manufacturer]
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  • Address: Synth?se AptoChem Inc.
    6100 Royalmount Ave
    Montreal, QC
    Canada
    H4P 2R2 ,Canada
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82-95-1 Buclizine base

  • Buclizine base
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
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  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
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References of 1-[(4-tert-butylphenyl)methyl]-4-[(4-chlorophenyl)-phenylmethyl]
piperazine
Title: Buclizine
CAS Registry Number: 82-95-1
CAS Name: 1-[(4-Chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]piperazine
Synonyms: 1-(p-tert-butylbenzyl)-4-(p-chloro-a-phenylbenzyl)piperazine; 1-(p-chlorobenzhydryl)-4-(p-tert-butylbenzyl)diethylenediamine; 1-(p-tert-butylbenzyl)-4-(p-chlorodiphenylmethyl)piperazine; histabutyzine; histabutizine
Molecular Formula: C28H33ClN2
Molecular Weight: 433.03
Percent Composition: C 77.66%, H 7.68%, Cl 8.19%, N 6.47%
Literature References: Prepn: Morren, US 2709169 (1955 to U.C.B.), see also DE 964040, Lui et al., C.A. 62, 2776a (1965). Clinical evaluation as antiemetic in migraine: P. B. Jorgensen et al., Curr. Ther. Res. 16, 1276 (1974); E. I. Adam, J. Int. Med. Res. 15, 71 (1987).
Properties: bp0.001 217-220°.
Boiling point: bp0.001 217-220°
 
Derivative Type: Dihydrochloride
CAS Registry Number: 129-74-8
Manufacturers' Codes: UCB-4445
Trademarks: Aphilan (UCB); Buclina (Sanofi-Synthelabo); Longifene (UCB); Postafen (UCB)
Molecular Formula: C28H33ClN2.2HCl
Molecular Weight: 505.95
Percent Composition: C 66.47%, H 6.97%, Cl 21.02%, N 5.54%
Properties: mp 230-240°.
Melting point: mp 230-240°
 
Therap-Cat: Antiemetic.
Keywords: Antiemetic.