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CAS No 83930-13-6 , Somatorelin

  • Name: Somatorelin
  • Synonyms: Human growth hormone-releasing hormone (1-44) amide;Somatoliberin (human); GRF (1-44) (human); Growth-hormone-releasing hormone;Somatorelin;
  • CAS Registry Number:
  • Molecular Weight: 5039.65
  • InChI: InChI=1S/C215H358N72O66S/c1-24-106(15)166(285-174(318)112(21)251-193(337)145(91-163(309)310)270-173(317)109(18)249-175(319)119(218)86-115-49-53-117(293)54-50-115)208(352)278-142(87-114-39-27-26-28-40-114)200(344)287-168(113(22)292)209(353)279-144(90-157(225)301)199(343)283-150(99-291)204(348)274-141(88-116-51-55-118(294)56-52-116)197(341)261-126(47-37-78-243-214(235)236)181(325)260-122(42-30-32-73-217)192(336)284-165(105(13)14)206(350)277-137(82-101(5)6)178(322)247-95-160(304)253-129(58-65-152(220)296)185(329)272-140(85-104(11)12)196(340)282-147(96-288)202(346)252-111(20)172(316)256-124(45-35-76-241-212(231)232)180(324)259-121(41-29-31-72-216)184(328)271-139(84-103(9)10)195(339)273-138(83-102(7)8)194(338)266-133(61-68-155(223)299)190(334)276-146(92-164(311)312)201(345)286-167(107(16)25-2)207(351)268-135(71-80-354-23)191(335)281-148(97-289)203(347)262-127(48-38-79-244-215(237)238)182(326)264-131(59-66-153(221)297)187(331)263-128(57-64-151(219)295)177(321)246-94-159(303)254-130(62-69-161(305)306)186(330)280-149(98-290)205(349)275-143(89-156(224)300)198(342)267-132(60-67-154(222)298)188(332)265-134(63-70-162(307)308)189(333)258-120(43-33-74-239-210(227)228)176(320)245-93-158(302)248-108(17)170(314)255-123(44-34-75-240-211(229)230)179(323)250-110(19)171(315)257-125(46-36-77-242-213(233)234)183(327)269-136(169(226)313)81-100(3)4/h26-28,39-40,49-56,100-113,119-150,165-168,288-294H,24-25,29-38,41-48,57-99,216-218H2,1-23H3,(H2,219,295)(H2,220,296)(H2,221,297)(H2,222,298)(H2,223,299)(H2,224,300)(H2,225,301)(H2,226,313)(H,245,320)(H,246,321)(H,247,322)(H,248,302)(H,249,319)(H,250,323)(H,251,337)(H,252,346)(H,253,304)(H,254,303)(H,255,314)(H,256,316)(H,257,315)(H,258,333)(H,259,324)(H,260,325)(H,261,341)(H,262,347)(H,263,331)(H,264,326)(H,265,332)(H,266,338)(H,267,342)(H,268,351)(H,269,327)(H,270,317)(H,271,328)(H,272,329)(H,273,339)(H,274,348)(H,275,349)(H,276,334)(H,277,350)(H,278,352)(H,279,353)(H,280,330)(H,281,335)(H,282,340)(H,283,343)(H,284,336)(H,285,318)(H,286,345)(H,287,344)(H,305,306)(H,307,308)(H,309,310)(H,311,312)(H4,227,228,239)(H4,229,230,240)(H4,231,232,241)(H4,233,234,242)(H4,235,236,243)(H4,237,238,244)/t106-,107-,108-,109-,110-,111-,112-,113+,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,165-,166-,167-,168-/m0/s1
  • Molecular Formula: C215H358N72O66S
  • Molecular Structure:CAS No:83930-13-6 Somatorelin
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83930-13-6 GRF(human)Acetate peptide

  • GRF(human)Acetate Sequence: Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2 Cas No.: 83930-13-6 Molecular Formula: C21...
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83930-13-6 GRF (human) Acetate

  • GHRH is a releasing hormone of growth hormone (GH). It is a 44-amino acid peptide hormone produced in the arcuate nucleus of the hypothalamus. GHRH is released from neurosecretory nerve terminals of these arcuate neurons, and is carried by the hypoth...
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83930-13-6 GRF(human)Acetate

  • Product Name GRF(human)Acetate Sequence Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly- Ala-Arg-Ala-Arg-Leu-NH2 Cas No. 83930-13-6 Molecular ...
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  • China Nanjing Bangnuo Biotechnology Co., Ltd [Manufacturer]
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83930-13-6 GRF(human)Acetate

  • GRF(human)Acetate/Cas No.: 83930-13-6 Purity (HPLC): 98.0%min. Appearance: White powder Molecular Formula: C215H358N72O66S Molecular Weight: 5039.76 Single Impurity (HPLC): 1.0%max Amino Acid Composition: ±10% of theoretical Peptide Content (N%): 80....
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83930-13-6 China High purity polypeptide GRF(human)Acetate

  • we are golden member and audited supplier high quality&favorable price guaranteed parcel can be sent out in 24 hours after payment tracking number available secure and discreet shippment express delivery with DHL,EMS,Fedex,HKEMS,TNT,UPS For more deta...
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83930-13-6 GRF (human) Acetate

  • GRF (human) Acetate Sequence:Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly- Ala-Arg-Ala-Arg-Leu-NH2 Cas No.:83930-13-6 Molecular Formula:C21...
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  • China Hubei Yuancheng Group [Manufacturer, Trading Company]
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83930-13-6 GRF (human) Acetate

  • GRF (human) Acetate Sequence:Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly- Ala-Arg-Ala-Arg-Leu-NH2 Cas No.:83930-13-6 Molecular Formula:C21...
  • Min. Order: 500
  • China Hubei Yuancheng Group [Manufacturer]
  • Tel: 86-027-50756063
  • Address: Zhongshan Road Wuhan,HubeiChina
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83930-13-6 GRF (human) Acetate

  • GRF (human) Acetate Sequence:Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly- Ala-Arg-Ala-Arg-Leu-NH2 Cas No.:83930-13-6 Molecular Formula:C21...
  • Min. Order: 500
  • China Wuhan Yuancheng Group [Manufacturer, Trading Company]
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  • Address: Zhongshan Road Wuhan,HubeiChina
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83930-13-6 GRF (human) Acetate

  • GRF (human) Acetate Sequence:Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly- Ala-Arg-Ala-Arg-Leu-NH2 Cas No.:83930-13-6 Molecular Formula:C21...
  • Min. Order: 500
  • China Hubei Saichuang Group [Manufacturer, Trading Company]
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  • Address: Zhongshan Road wuhan,HubeiChina
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83930-13-6 GRF (human) Acetate

  • GRF (human) Acetate Sequence:Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly- Ala-Arg-Ala-Arg-Leu-NH2 Cas No.:83930-13-6 Molecular Formula:C21...
  • Min. Order: 500
  • China Hubei Gongchuang Group [Manufacturer, Trading Company]
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References of Somatorelin
Title: Somatoliberin
CAS Registry Number: 83930-13-6
CAS Name: Growth hormone-releasing factor
Synonyms: GH-RF; GH-RH; GRF; growth hormone-releasing hormone; hGRF; hpGRF; somatocrinin
Literature References: Stimulatory growth-hormone releasing factor of the hypothalamus that mediates, together with somatostatin, q.v., the neuroregulation of somatotropin secretion. The concept of hypothalamic regulation of growth hormone release was postulated on the basis of physiological and biochemical evidence, cf. A. V. Schally et al., Recent Prog. Horm. Res. 24, 497 (1968); J. B. Martin in Frontiers in Neuroendocrinology, L. Martini, W. F. Ganong, Eds. (Raven Press, New York, 1976) pp 129-168. Demonstration of the existence of a GH-RH: R. Deuben, J. Meites, Endocrinology 74, 408 (1964); A. V. Schally et al., ibid. 82, 271 (1968); E. Dickermann et al., Neuroendocrinology 4, 75 (1969). Isoln of a decapeptide originally believed to be GRF: A. V. Schally et al., Endocrinology 84, 1493 (1969). Review of early literature: eidem, Science 179, 341 (1973). Isoln and characterization of hpGRF, a fully bioactive, 44 amino acid peptide from human pancreatic tumor: R. Guillemin et al., Science 218, 585 (1982); J. Rivier et al., Nature 300, 276 (1982). Cloning and sequence analysis of cDNA for hpGRF precursor: U. Gubler et al., Proc. Natl. Acad. Sci. USA 80, 4311 (1983). Expression-cloning of cDNA for hpGRF: K. E. Mayo et al., Nature 306, 86 (1983). Isoln, primary structure and synthesis of native human hypothalamic GRF (hGRF), identity with hpGRF and comparison with GRF from other species: N. Ling et al., Proc. Natl. Acad. Sci. USA 81, 4302 (1984). Immunohistochemical detection of GRF in brain: B. Bloch et al., ibid. 301, 607 (1983). Potent interaction of glucocorticoids with GRF in vivo: W. B. Wehrenberg et al., Science 221, 556 (1983). Series of articles on clinical pharmacology: Horm. Res. 22, 32-57 (1985). Clinical evaluation in treatment of hypopituitary dwarfism: M. O. Thorner et al., N. Engl. J. Med. 312, 4 (1985). Reviews: R. Guillemin et al., Recent Prog. Horm. Res. 40, 233-299 (1984); W. B. Wehrenberg et al., Annu. Rev. Pharmacol. Toxicol. 25, 463-483 (1985).
Properties: Porcine GRF is destroyed by trypsin, chymotrypsin, pepsin. Biological activity remains after incubation at pH 8.5 for 4 hours at 37°, but is destroyed after similar incubation at pH 2.