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CAS No 84-80-0 , Vitamin K1

  • Name: Vitamin K1
  • Synonyms: 2-Methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-1,4-naphthalenedione; Vitamin K_1; 2-methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-1,4-naphthalenedione; Phytonadione;phytomenadione; 2-Methyl-3-phytyl-1,4-naphthoquinone;Vitamin K1; Phylloquinone;2-Methyl-3-phytyl-1,4-naphthoquinone;
  • CAS Registry Number:
  • Melting Point: -20 ºC
  • Boiling Point: 140°C 0mm
  • Density: 0.984
  • Refractive index: 1.527
  • Water Solubility: Practically insoluble in water,sparingly soluble in
  • Safety Statements: Moderately toxic by subcutaneous route. Mildly toxic by ingestion. An FDA proprietary drug. Used as a vitamin. When heated to decomposition it emits acrid smoke and irritating fumes.
  • Hazard Symbols: Xi
  • EINECS: 201-564-2
  • Molecular Weight: 450.70
  • InChI: InChI=1/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+
  • Risk Statements: 36/37/38
  • Molecular Formula: C31H46O2
  • Molecular Structure:CAS No:84-80-0 Vitamin K1
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84-80-0 Vitamin K1 (Phylloquinone) (Ring-D4, 98%)

  • Creative Proteomics provides a full range of drug development services, including Molecular Biology, Biochemistry, Systems Biology, Organic Chemistry, Genomics, Bioinformatics, Structural Biology, Preclinical and Clinical studies. Please contact us t...
  • United States Creative Proteomics [Manufacturer, Trading Company]
  • Tel: 1-631-6197922
  • Fax: 1-631-6147828
  • Address: 45-1 Ramsey Road, Shirley New York,New YorkUnited States
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84-80-0 Vitamin K1 (Phylloquinone) (D7,99%) Chem. Purity 97%

  • Creative Proteomics provides a full range of drug development services, including Molecular Biology, Biochemistry, Systems Biology, Organic Chemistry, Genomics, Bioinformatics, Structural Biology, Preclinical and Clinical studies. Please contact us t...
  • United States Creative Proteomics [Manufacturer, Trading Company]
  • Tel: 1-631-6197922
  • Fax: 1-631-6147828
  • Address: 45-1 Ramsey Road, Shirley New York,New YorkUnited States
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84-80-0 VITAMIN K1

  • Germany ABCR GmbH & Co KG [Manufacturer]
  • Tel: +49 721 95061-0
  • Fax: +49 721 95061-80
  • Address: Im Schlehert 10
    76187 Karlsruhe
    Germany ,Germany
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84-80-0 Vitamin K1 (phytonadione)

  • Vitamin K1 (phytonadione) Product details Vitamin K1 (phytonadione) Product Name: Vitamin K1 (phytonadione) Synonyms: phytomenadione; 2-Methyl-3-phytyl-1,4-naphthoquinone; 2-methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-1,4-naphthalenedione; Phytona...
  • China Wuhan Yuancheng Group [Manufacturer]
  • Tel: 86-027-50756063
  • Address: Zhongshan Road Wuchang Wuhan,HubeiChina
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84-80-0 Vitamin K1(CAS:84-80-0)

  • Vitamin K1(CAS:84-80-0) Email:dahuamanager@whdhwy.com Skype:selenayang07 Whatsapp:+8615623826482 Synonyms:Monodion;Orakay;Phylloquinone K1;Phytonadione;Phytylmenadione;Synthex P;Veda K1;VitaminK1(20) CAS:84-80-0 Formula:C31H46O2 Molecular Weight:450....
  • Min. Order: 10000
  • China Wuhan Dahua Weiye Pharmaceutical Co.,Ltd [Manufacturer]
  • Tel: 86-27-59848232
  • Fax: 86-27-59420980
  • Address: No. 45 Daijiangshan Jiangan District, Wuhan, Hubei, China Wuhan,HubeiChina
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84-80-0 Vitamin K1

  • Vitamin K1 Chemical name : 2-Methyl-3-phytyl-1,4-naphthoquinone; Phylloquinone; CAS number : 84-80-0 Molecular Formula: C31H46O2 Molecular weight : 450.70 Sep: CP2005 Appearance: packing: 5kg/tin Assay: 5% Melting point: -20℃
  • China Wuhan Changland Technology Co.Ltd [Manufacturer]
  • Tel: 86-27-87290719
  • Fax: 86-27-68786490
  • Address: Changland Technology Co.,LTD Wuhan,HubeiChina
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84-80-0 2-METHYL-3-PHYTYL-1,4-NAPHTHOQUINONE

  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany ,Germany
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84-80-0 vitamin K1

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84-80-0 vitamin K1

  • China Shanghai Xunxin Chemical Co., Ltd [Manufacturers]
  • Tel: +86-(21)-38218795
  • Fax: +86-(21)-38218795
  • Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315, Shanghai,ShanghaiChina
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84-80-0 Vitamin K1

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References of Vitamin K1
Title: Phylloquinone
CAS Registry Number: 84-80-0
CAS Name: 2-Methyl-3-[(2E,7R,11R)-3,7,11,15-tetramethyl-2-hexadecenyl]-1,4-naphthalenedione
Synonyms: 2-methyl-3-phytyl-1,4-naphthoquinone; 3-phytylmenadione; phytomenadione; phytonadione; vitamin K1
Trademarks: AquaMephyton (Merck & Co.); Konakion (Roche); Mephyton (Merck & Co.); Mono-Kay (Abbott); Veda-K1 (Vedco); Veta-K1 (Sanofi)
Molecular Formula: C31H46O2
Molecular Weight: 450.70
Percent Composition: C 82.61%, H 10.29%, O 7.10%
Literature References: Photosynthetic electron carrier; occurs widely in green plants, algae, photosynthetic bacteria. Major dietary source of vitamin K, q.v. Isoln from alfalfa: H. Dam et al., Helv. Chim. Acta 22, 310 (1939). Structure: D. W. MacCorquodale et al., J. Biol. Chem. 131, 357 (1939); L. F. Fieser, J. Am. Chem. Soc. 61, 3467 (1939). Partial syntheses from menadione and phytol: H. J. Almquist, A. A. Klose, ibid. 2557; S. B. Binkley et al., ibid. 2558; L. F. Fieser, ibid. 2559. Stereochemistry and total synthesis: H. Mayer et al., Helv. Chim. Acta 47, 221 (1964); L. M. Jackman et al., ibid. 48, 1332 (1965). Synthesis using a p-allylic nickel(I) complex: Sato et al., J. Chem. Soc. Perkin Trans. 1 1973, 2289. Alternate synthesis: Y. Tachibana, Chem. Lett. 1977, 901. Metabolic studies: M. J. Shearer et al., Br. J. Haematol. 18, 297 (1970); 22, 579 (1972). The cis isomer is not bioactive: J. T. Matschiner et al., J. Nutr. 102, 625 (1972). Isoln from chloroplasts: E. Interschick-Niebler, H. K. Lichtenthaler, Z. Naturforsch. 36C 276 (1981). Role in photosystem I: K. Brettel et al., FEBS Lett. 203, 220 (1986). Conversion in vivo to menaquinone-4, q.v.: H. H. W. Thijssen, M. J. Drittij-Reijnders, Br. J. Nutr. 72, 415 (1994). HPLC determn in foods: S. L. Booth et al., J. Agric. Food Chem. 42, 295 (1994). Clinical efficacy in hemorrhagic disease of newborn: P. M. Loughnan, P. N. McDougall, J. Paediatr. Child Health 29, 171 (1993). Comprehensive description: M. M. A. Hassan et al., Anal. Profiles Drug Subs. 17, 449-531 (1988).
Properties: Yellow viscous oil. [a]D25 -0.28° (dioxane). nD20 1.5263. uv max (petr ether): 242, 248, 260, 269, 325 nm (E1%1cm 396, 419, 383, 387, 68). Insol in water. Sparingly sol in methanol; sol in ethanol, acetone, benzene, petr ether, hexane, dioxane, chloroform, ether, other fat solvents and in vegetable oils. Stable to air and moisture, but dec in sunlight. Unaffected by dil acids, but destroyed by solns of alkali hydroxides and by reducing agents. Keep well closed and protected from light.
Optical Rotation: [a]D25 -0.28° (dioxane)
Index of refraction: nD20 1.5263
Absorption maximum: uv max (petr ether): 242, 248, 260, 269, 325 nm (E1%1cm 396, 419, 383, 387, 68)
 
Derivative Type: Dihydro form
CAS Registry Number: 572-96-3
Synonyms: Phytonadiol; dihydrovitamin K1; a-phyllohydroquinone
Properties: Waxy mass. Freely sol in ether; sparingly sol in petr ether. Insol in water.
 
Derivative Type: Dihydro form sodium diphosphate
CAS Registry Number: 5988-22-7
Synonyms: Phytonadiol sodium diphosphate; Kayhydrin
Molecular Formula: C31H48Na2O8P2
Molecular Weight: 656.64
Percent Composition: C 56.70%, H 7.37%, Na 7.00%, O 19.49%, P 9.43%
Properties: mp 138°. Sol in water and methanol.
Melting point: mp 138°
 
Derivative Type: 2,3-Epoxide
CAS Registry Number: 25486-55-9
Synonyms: Vitamin K1 epoxide; vitamin K1 oxide
Molecular Formula: C31H46O3
Molecular Weight: 466.70
Percent Composition: C 79.78%, H 9.93%, O 10.28%
Literature References: Prepn: Fieser et al., J. Am. Chem. Soc. 61, 3216 (1939).
Properties: Colorless oil. uv max (95% alc): 259, 305 nm (log EM 3.79, 3.31). Insol in water.
Absorption maximum: uv max (95% alc): 259, 305 nm (log EM 3.79, 3.31)
 
Therap-Cat: Vitamin (prothrombogenic).
Therap-Cat-Vet: Vitamin (prothrombogenic); antidote for dicoumarol poisoning.
Keywords: Vitamin/Vitamin Source; Vitamin K.