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CAS No 85-73-4 , 2-[[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]carbamoyl]benzoic acid

  • Name: 2-[[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]carbamoyl]benzoic acid
  • Synonyms: Phthalylsulphathiazole; Phthalylnorsulfazole; Phthaloylsulfathiazole; 85-73-4;2-[[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]carbamoyl]benzoic acid;Sulfathalidine; Phthalazole; Phthalazol; Phthalylsulfonazole;
  • CAS Registry Number:
  • Transport: 3249
  • Melting Point: 198-204 ºC
  • Density: 1.596 g/cm3
  • Safety Statements: Moderately toxic by intraperitoneal route. When heated to decomposition it emits very toxic fumes of NOx and SOx.
  • EINECS: 201-627-4
  • Molecular Weight: 403.43222
  • InchiKey: PBMSWVPMRUJMPE-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H13N3O5S2/c21-15(13-3-1-2-4-14(13)16(22)23)19-11-5-7-12(8-6-
    11)27(24,25)20-17-18-9-10-26-17/h1-10H,(H,18,20)(H,19,21)(H,22,23)
  • Molecular Formula: C17H13N3O5S2
  • Molecular Structure:CAS No:85-73-4 2-[[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]carbamoyl]benzoic acid
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85-73-4 4''-(2-THIAZOLYLSULFAMYL)PHTHALANILIC ACID; 95%

  • Germany ABCR GmbH & Co KG [Manufacturer]
  • Tel: +49 721 95061-0
  • Fax: +49 721 95061-80
  • Address: Im Schlehert 10
    76187 Karlsruhe
    Germany ,Germany
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85-73-4 Phthalylsulphathiazole

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85-73-4 Phthalylsulphathiazole

  • China Xilin Chemical Group Co., Ltd []
  • Tel: +86-(0)-15527136576
  • Fax: +86-(27)-83820093
  • Address: 16# Luojiashan, Wuchang District, Wuhan, Hubei 430071, ,China
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85-73-4 PHTHALYLSULFATHIAZOLE

  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany ,Germany
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85-73-4 Phthalylsulfathiazole

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85-73-4 Phthalylsulfathiazole

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85-73-4 PHTHALYLSULPHATHIAZOLE

  • India JAI RADHE SALES []
  • Fax: 0091-79-26569884
  • Address: 309/310 HARIKRUPA TOWER,NR.OLD SHARDA MANDIR CHAR RASTA,ELLISBRIDGE ,AHMEDABAD,GUJRAT , INDIA. ,India
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85-73-4 Phthalylsulfathiazole

  • United States Tecoland Corporation []
  • Tel: +1-(732)-603-9577
  • Fax: +1-(732)-906-1522
  • Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428, ,United States
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85-73-4 PHTHALYLSULFATHIAZOLE

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85-73-4 Phthalylsulfathiazole

  • China Kingland Chemicals Company Limited [Manufacturers]
  • Tel: +86-571-87211518,87229835
  • Fax: +86-571-87211508
  • Address: Room No. 1806-1808, Jinfeng Mansion, No.281 Zhong He Zhong Road, Hangzhou, China. ,zhejiangChina
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References of 2-[[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]carbamoyl]benzoic acid
Title: Phthalylsulfathiazole
CAS Registry Number: 85-73-4
CAS Name: 2-[[[4-[(2-Thiazolylamino)sulfonyl]phenyl]amino]carbonyl]benzoic acid
Synonyms: 4¢-(2-thiazolylsulfamyl)phthalanilic acid; 2-(N4-phthalylaminobenzenesulfonamido)thiazole; 2-(N4-phthalylsulfanilamido)thiazole; phthalylsulfonazole
Trademarks: Estreptocarbocaftiazol (Bago); Thalazole (M & B)
Molecular Formula: C17H13N3O5S2
Molecular Weight: 403.43
Percent Composition: C 50.61%, H 3.25%, N 10.42%, O 19.83%, S 15.90%
Literature References: May be prepd by condensing sulfathiazole with phthalic anhydride: M. L. Moore, US 2324013; US 2324015 (1943 to Sharp & Dohme). Prepn of 8-hydroxyquinoline salt: DE 1008296 (1957 to Geistlich S?hne). Toxicity data: P. A. Mattis et al., J. Pharmacol. Exp. Ther. 81, 116 (1944).
Properties: Crystals. Slightly bitter taste. Darkens on prolonged exposure to light. Effervesces at 244° to 250°. mp 272-277° (dec) when the melting point bath is preheated to 220-225°. Slightly sol in alcohol; very slightly sol in ether; readily sol in NaOH or KOH soln, ammonia water and concd HCl. Practically insol in chloroform and water. LD50 i.p. in mice: 920 mg/kg (Mattis).
Melting point: mp 272-277° (dec) when the melting point bath is preheated to 220-225°
Toxicity data: LD50 i.p. in mice: 920 mg/kg (Mattis)
 
Derivative Type: 8-Hydroxyquinoline salt
Properties: Yellow crystals from dil methanol, dec above 220°. Split into its components by dil acids.
 
Therap-Cat: Antibacterial.
Therap-Cat-Vet: Antibacterial.
Keywords: Antibacterial (Synthetic); Sulfonamides.