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CAS No 85233-19-8 , 2-[2-[2-[2-[bis(carboxymethyl)amino]phenoxy]ethoxy]-N-(carboxymethyl)
anilino]acetic acid Search by region : Germany

  • Name: 2-[2-[2-[2-[bis(carboxymethyl)amino]phenoxy]ethoxy]-N-(carboxymethyl)
    anilino]acetic acid
  • Synonyms: Ca(II)-bapta; 5F-Bapta; Bapeta;BAPTA; 85233-19-8; 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid;2-[2-[2-[2-[bis(carboxymethyl)amino]phenoxy]ethoxy]-N-(carboxymethyl)
    anilino]acetic acid;
  • CAS Registry Number:
  • Flash Point: 417.4°C
  • Boiling Point: 766.6°C at 760 mmHg
  • Density: 1.494 g/cm3
  • Safety Statements:
    Hazard Codes Xi
    Risk Statements 36/37/38
    Safety Statements 26-36
    WGK Germany 3
  • Hazard Symbols: Xi: Irritant;
  • Flash Point: 417.4°C
  • Molecular Weight: 476.43336
  • InchiKey: FTEDXVNDVHYDQW-UHFFFAOYSA-N
  • InChI: InChI=1S/C22H24N2O10/c25-19(26)11-23(12-20(27)28)15-5-1-3-7-17(15)33-9-
    10-34-18-8-4-2-6-16(18)24(13-21(29)30)14-22(31)32/h1-8H,9-14H2,(H,25,
    26)(H,27,28)(H,29,30)(H,31,32)
  • Risk Statements: S24/25:Avoidcontactwithskinandeyes.;
  • Molecular Formula: C22H24N2O10
  • Molecular Structure:CAS No:85233-19-8 2-[2-[2-[2-[bis(carboxymethyl)amino]phenoxy]ethoxy]-N-(carboxymethyl)<br />anilino]acetic acid

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85233-19-8 BAPTA; 97%

  • BAPTA; 97%
  • Germany ABCR GmbH & Co KG [Manufacturer]
  • Tel: +49 721 95061-0
  • Fax: +49 721 95061-80
  • Address: Im Schlehert 10
    76187 Karlsruhe
    Germany null,nullGermany
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85233-19-8 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid

  • 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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References of 2-[2-[2-[2-[bis(carboxymethyl)amino]phenoxy]ethoxy]-N-(carboxymethyl)
anilino]acetic acid
Title: BAPTA
CAS Registry Number: 85233-19-8
CAS Name: N,N￠-[1,2-Ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)glycine]
Synonyms: 1,2-bis(2-aminophenoxy)ethane-N,N,N￠,N￠-tetraacetic acid
Molecular Formula: C22H24N2O10
Molecular Weight: 476.43
Percent Composition: C 55.46%, H 5.08%, N 5.88%, O 33.58%
Literature References: Calcium (Ca2+) chelator derived from EGTA. Ca2+ binding causes a shift in the uv absorbance and fluorescence of the molecule. Parent compound of second generation fluorescent imaging agents such as Indo-1, Fura-2, q.q.v. Prepn: R. Y. Tsien, Biochemistry 19, 2396 (1980). Dissociation constants: R. Pethig et al., Cell Calcium 10, 491 (1989). Use as chelator: P. W. Marks, F. R. Maxfield, Anal. Biochem. 193, 61 (1991). Binding constants and fluorescence with heavy metals: A. Yuchi et al., Bull. Chem. Soc. Jpn. 66, 3377 (1993). Prepn of 19F-forms and use for intracellular Ca2+ measurement: G. A. Smith et al., Proc. Natl. Acad. Sci. USA 80, 7178 (1983); L. A. Levy et al., Am. J. Physiol. 252, C441 (1987). NMR determn of Ca2+ in brain by 5F-BAPTA: H. S. Bachelard et al., J. Neurochem. 51, 1311 (1988).
Properties: uv max (free dye): 209, 254 nm (e 3.8 ′ 104, 1.6 ′ 104). uv max (complexed form): 203, 274 nm (e 4.1 ′ 104, 4.2 ′103).
Absorption maximum: uv max (free dye): 209, 254 nm (e 3.8 ′ 104, 1.6 ′ 104); uv max (complexed form): 203, 274 nm (e 4.1 ′ 104, 4.2 ′103)
Use: As calcium chelator; 19F labelled forms for measurement of intracellular calcium.