Home > Name List By 4 > 4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol

CAS No 86-42-0 , 4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol

  • Name: 4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol
  • Synonyms: Flavoquine; Camoquinal;4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol; Miaquin; Camoquine; Amodiachinum; Cam-AQ1; Camochin;Amodiaquin; Camoquin;
  • CAS Registry Number:
  • Melting Point: 208 ºC
  • Density: 1.258
  • EINECS: 201-669-3
  • Molecular Weight: 355.86118
  • InchiKey: OVCDSSHSILBFBN-UHFFFAOYSA-N
  • InChI: InChI=1S/C20H22ClN3O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-
    19-12-15(21)5-7-17(18)19/h5-12,25H,3-4,13H2,1-2H3,(H,22,23)
  • Molecular Formula: C20H22ClN3O
  • Molecular Structure:CAS No:86-42-0 4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol
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86-42-0 Amodiaquin

  • China Chemrio International Limited [Manufacturer]
  • Tel: +86 574 2789 1268/ +86-139 5789 5864 (mobile)
  • Fax: +86 574 2789 1266
  • Address: Chemrio International Limited
    Room 611-612, Wante Business Center
    No.487 Yangmuqi Road,
    Hi-tech Park Ningbo, 315040,China ,China
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86-42-0 Amodiaquine

  • Amodiaquine4-(7-chloro-4-quinolylamino)-alpha-diethylamino-o-cresol, 99.0%MIN
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,China
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86-42-0 Amodiaquine

  • Amodiaquine
  • China Betapharma Shanghai Inc.Co., Ltd [Manufacturer]
  • Tel: 86-21-62951620
  • Fax: 86-21-32230794
  • Address: Jinming Building 12A No. 8 Zunyi(S) Rd. Shanghai China 200336 shanghaiCHINA shanghai,China
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86-42-0 Amodiaquin

  • China Shanghai Xunxin Chemical Co., Ltd [Manufacturers]
  • Tel: +86-(21)-38218795
  • Fax: +86-(21)-38218795
  • Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315, Shanghai,ShanghaiChina
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86-42-0 Amodiaquine

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86-42-0 Amodiaquin

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86-42-0 Amodiaquin

  • China Haihang Industry Co., Ltd. []
  • Tel: +86-(531)-88032799
  • Fax: +86-(531)-85821093
  • Address: 2/F, East Tower, Bldg 12, No. 2 Qilihe Road, Jinan 250100, ,China
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86-42-0 Amodiaquine Base

  • India Manus Aktteva []
  • Tel: +91-(79)-65123395
  • Fax: +91-(79)-26463395
  • Address: 303, 3rd Floor, Royale Manor, Law Garden, Dhulia Kot Road, Ellisbridge, Ahmedabad, Gujarat 380006, ,India
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86-42-0 Amodiaquine Base

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86-42-0 Amodiaquin

  • China Betapharma(Shanghai)Co., Ltd. []
  • Tel: +86-(21)-33538380
  • Fax: +86-(21)-32082820
  • Address: No.17#-6D. 830 Lane, Maotai Road, Shanghai 200336, ,China
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References of 4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol
Title: Amodiaquin
CAS Registry Number: 86-42-0
CAS Name: 4-[(7-Chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]phenol
Synonyms: 4-[(7-chloro-4-quinolyl)amino]-a-(diethylamino)-o-cresol; 7-chloro-4-(3-diethylaminomethyl-4-hydroxyanilino)quinoline; 7-chloro-4-(3-diethylaminomethyl-4-hydroxyphenylamino)quinoline; 4-(3¢-diethylaminomethyl-4¢-hydroxyanilino)-7-chloroquinoline
Manufacturers' Codes: SN-10751
Molecular Formula: C20H22ClN3O
Molecular Weight: 355.86
Percent Composition: C 67.50%, H 6.23%, Cl 9.96%, N 11.81%, O 4.50%
Literature References: Prepd from 4,7-dichloroquinoline and 4-acetamido-a-diethylamino-o-cresol: Burckhalter et al., J. Am. Chem. Soc. 70, 1363 (1948); US 2474819; US 2474821 (1949 to Parke, Davis). Alternate synthesis from 2-aminomethyl-p-aminophenol and 4,7-dichloroquinoline: Natarajan, Lan, Arzneim.-Forsch. 22, 1230 (1972). Spectral study: J. Kracmar et al, Pharmazie 29, 773 (1974). HPLC determn in plasma, blood and urine: E. Pussard et al., J. Chromatogr. 374, 111 (1986). Comprehensive description: I. Ahmad et al., Anal. Profiles Drug Subs. 21, 43-73 (1992).
Properties: Crystals from abs. ethanol, mp 208° (dec).
Melting point: mp 208° (dec)
 
Derivative Type: Dihydrochloride dihydrate
CAS Registry Number: 6398-98-7
Synonyms: CAM-AQ1
Trademarks: Camoquin (Parke-Davis); Flavoquine (Aventis)
Molecular Formula: C20H22ClN3O.2HCl.2H2O
Molecular Weight: 464.81
Percent Composition: C 51.68%, H 6.07%, Cl 22.88%, N 9.04%, O 10.33%
Properties: Yellow, bitter crystals, dec 150-160°. uv max (methanol): 342 nm (E1%1cm 349); (water): 341.5 nm (E1%1cm 389); (0.1N HCl): 342 nm (E1%1cm 396). Sol in water; sparingly sol in alc; very slightly sol in benzene, chloroform, ether. pH of 1% aq soln 4.0 to 4.8.
Absorption maximum: uv max (methanol): 342 nm (E1%1cm 349); (water): 341.5 nm (E1%1cm 389); (0.1N HCl): 342 nm (E1%1cm 396)
 
Derivative Type: Dihydrochloride hemihydrate
Properties: Yellow crystals from methanol, mp 243°. Slightly sol in water, alc.
Melting point: mp 243°
 
Therap-Cat: Antimalarial.
Keywords: Antimalarial.