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CAS No 88495-63-0 , Artesunate

  • Name: Artesunate
  • Synonyms: Arteannuinum;Artesunate; Butanedioic Acid Mono(3R,5aS,6R,8aS,9R,10R,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] Ester; Artesunic Acid;ArtesunateC19H28O8; Artemisinin monosuccinate; Arteannuinum succinate; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin-10-ol hydrogen succinate;
  • CAS Registry Number:
  • Melting Point: 132-1350C
  • Density: 1.31 g/cm3
  • Refractive index: 1.543
  • Safety Statements: 20/21/22,
  • Hazard Symbols: Xn:;
  • Molecular Weight: 384.42
  • InChI: InChI=1/C19H28O8/c1-10-4-5-13-11(2)16(23-15(22)7-6-14(20)21)24-17-19(13)12(10)8-9-18(3,25-17)26-27-19/h10-13,16-17H,4-9H2,1-3H3,(H,20,21)/t10-,11-,12+,13+,16+,17-,18-,19-/m1/s1
  • Risk Statements: 20/21/22
  • Molecular Formula: C19H28O8
  • Molecular Structure:CAS No:88495-63-0 Artesunate
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88495-63-0 Artesunate

  • Synonym: ARTESUNATE;ArtesunateC19H28O8;Artemisinin monosuccinate;Artesunic Acid;Butanedioic Acid Mono(3R,5aS,6R,8aS,9R,10R,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] Ester;Arteannuinum;Arteannuinum succi...
  • China Hubei Yuancheng Gongchuang Technology Co.,Ltd [Manufacturer]
  • Tel: 86-027-50756226
  • Address: No.496,Zhongshan Road, Wuhan, Hubei, China wuhan,HubeiChina
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88495-63-0 Artesunate for treatment malaria

  • White color cream crystalline powder Artesunate for treatment malaria Skyp : Hormonepowder chen winnie@chembj.com Keywords High quality Artesunate competitive price Artesunate Artesunate supplier Quick Details ProName:Artesunate CasNo:88495-63-0 Appe...
  • China Shenzhen Simeiquan Biotechnology Co., Ltd. [Manufacturer]
  • Tel: 86-27-50756083
  • Address: New Area Road, Minzhi Street, Longhua New Area, Shenzhen shenzhen,GuangdongChina
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88495-63-0 Artesunate

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi ,ShanXiChina
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88495-63-0 ARTESUNATE 99% BY UV

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong ,Hong kong
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88495-63-0 Artesunate

  • China Trust&We Co., Ltd. [Manufacturer]
  • Tel: +86-21-61044582
  • Fax: +86-21-61044583
  • Address: 1-102,No.11,Dongjiaominxiang Alley,
    Dongcheng District,
    Beijing 100005,China ,China
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88495-63-0 Artesunate

  • China YiPeng Chemical [Manufacturers]
  • Tel: 571 85376369
  • Fax: 571 88233092
  • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China ,ZheJiangChina
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88495-63-0 Artesunate

  • China Shanghai Xunxin Chemical Co., Ltd [Manufacturers]
  • Tel: +86-(21)-38218795
  • Fax: +86-(21)-38218795
  • Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315, Shanghai,ShanghaiChina
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88495-63-0 Artesunate

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88495-63-0 Artesunate

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88495-63-0 Artesunate

  • China China Langchem Inc. []
  • Tel: +86-(21)-58956006
  • Fax: +86-(21)-58956100
  • Address: 514 Room, 1# Building, 88# Cailun Road, Zhangjiang High Tech Park, Shanghai 201203, ,China
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References of Artesunate
Title: Artesunate
CAS Registry Number: 88495-63-0
CAS Name: Butanedioic acid mono[(3R,5aS,6R,8aS,9R,10R,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] ester
Synonyms: artesunic acid; dihydroqinghaosu hemisuccinate
Molecular Formula: C19H28O8
Molecular Weight: 384.42
Percent Composition: C 59.36%, H 7.34%, O 33.30%
Literature References: Derivative of artemisinin, q.v. Prepn: China Cooperative Research Group on Qinghaosu, J. Tradit. Chin. Med. 2, 9 (1982). Absolute configuration: X.-D. Luo et al., Helv. Chim. Acta 67, 1515 (1984). GC/MS determn.: A. D. Theoharides et al., Anal. Chem. 60, 115 (1988); HPLC determn in plasma: H. Naik et al., J. Chromatogr. B 816, 233 (2005). Pharmacology: Y. Zhao, J. Trop. Med. Hyg. 88, 391 (1985). Antimalarial activity: W. Peters et al., Ann. Trop. Med. Parasitol. 80, 483 (1986); A. J. Lin et al., J. Med. Chem. 30, 2147 (1987). Inhibition of cytochrome oxidase: Y. Zhao et al., J. Nat. Prod. 49, 139 (1986). Toxicology: China Cooperative Research Group on Qinghaosu, J. Tradit. Chin. Med. 2, 31 (1982). Series of articles on chemistry, pharmacology, and antimalarial efficacy: ibid. 3-50. Clinical trial as add-on therapy in pediatric malaria: L. von Seidlein et al., Lancet 355, 352 (2000). Review: R. N. Price, Expert Opin. Invest. Drugs 9, 1815-1827 (2000).
Properties: Fine white crystalline powder.
 
Derivative Type: Sodium salt
Manufacturers' Codes: SM-804
Molecular Formula: C19H27NaO8
Molecular Weight: 406.40
Percent Composition: C 56.15%, H 6.70%, Na 5.66%, O 31.49%
Properties: Poor stability in aqueous solutions. LD50 in mice (mg/kg): 520 i.v.; 475 i.m. (China Cooperative Research Group); also reported as 699 ± 58.5 i.v. (Zhao, 1985).
Toxicity data: LD50 in mice (mg/kg): 520 i.v.; 475 i.m. (China Cooperative Research Group); also reported as 699 ± 58.5 i.v. (Zhao, 1985)
 
Therap-Cat: Antimalarial.
Keywords: Antimalarial.