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CAS No 886-74-8 , [3-(4-chlorophenoxy)-2-hydroxypropyl] carbamate Search by region : Germany

  • Name: [3-(4-chlorophenoxy)-2-hydroxypropyl] carbamate
  • Synonyms: Rinlaxer; 886-74-8;[3-(4-chlorophenoxy)-2-hydroxypropyl] carbamate; Chlorphensin carbamate;Maolate; 3-(4-Chlorophenoxy)-2-hydroxypropyl carbamate; Kolpicortin-sine;
  • CAS Registry Number:
  • Flash Point: 245.2°C
  • Boiling Point: 481.8°C at 760 mmHg
  • Density: 1.365g/cm3
  • Refractive index: 1.564
  • Safety Statements: Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Human systemic effects by ingestion: somnolence, hallucinations or distorted perceptions, and muscle weakness. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of Cl− and NOx. See also CARBAMATES.
  • Flash Point: 245.2°C
  • EINECS: 212-954-7
  • Molecular Weight: 245.65958
  • InchiKey: SKPLBLUECSEIFO-UHFFFAOYSA-N
  • InChI: InChI=1S/C10H12ClNO4/c11-7-1-3-9(4-2-7)15-5-8(13)6-16-10(12)14/h1-4,8,
    13H,5-6H2,(H2,12,14)
  • Molecular Formula: C10H12ClNO4
  • Molecular Structure:CAS No:886-74-8 [3-(4-chlorophenoxy)-2-hydroxypropyl] carbamate

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886-74-8 Chlorphenesin carbamate

  • Chlorphenesin carbamate
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References of [3-(4-chlorophenoxy)-2-hydroxypropyl] carbamate
Title: Chlorphenesin Carbamate
CAS Registry Number: 886-74-8
CAS Name: 3-(4-Chlorophenoxy)-1,2-propanediol-1-carbamate
Synonyms: carbamic acid 3-(p-chlorophenoxy)-2-hydroxypropyl ester; 3-(p-chlorophenoxy)-2-hydroxypropyl carbamate; 1,2-propanediol-3-(p-chlorophenoxy)-1-carbamate
Trademarks: Maolate (Upjohn); Rinlaxer (Taisho)
Molecular Formula: C10H12ClNO4
Molecular Weight: 245.66
Percent Composition: C 48.89%, H 4.92%, Cl 14.43%, N 5.70%, O 26.05%
Literature References: Prepn: Collins, Matthews, US 3161567; Parker, US 3214336 (1964, 1965 both to Upjohn). Clinical evaluation of analgesic activity: L. J. Cass, W. S. Frederick, J. New Drugs 2, 366 (1962).
Properties: Crystals from benzene + toluene, mp 89-91°. Readily sol in 95% ethanol, acetone, ethyl acetate; fairly readily sol in dioxane. Almost insol in cold water, benzene, cyclohexane. LD50 orally in rats: 748 mg/kg; i.v. in mice: 239 mg/kg (Cass, Frederick).
Melting point: mp 89-91°
Toxicity data: LD50 orally in rats: 748 mg/kg; i.v. in mice: 239 mg/kg (Cass, Frederick)
Therap-Cat: Muscle relaxant (skeletal).
Therap-Cat-Vet: Muscle relaxant (skeletal).
Keywords: Muscle Relaxant (Skeletal).