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CAS No 89667-40-3 , (E)-7-phenyl-7-pyridin-3-ylhept-6-enoic acid

  • Name: (E)-7-phenyl-7-pyridin-3-ylhept-6-enoic acid
  • Synonyms: (E)-7-Phenyl-7-(3-pyridyl)-6-heptenoic acid; Isbogrelum [INN-Latin];(E)-7-phenyl-7-pyridin-3-ylhept-6-enoic acid;Cv-4151; BRN 4257992; CV 4151; NCGC00160351-01; CCRIS 7236;
  • CAS Registry Number:
  • Flash Point: 245.1°C
  • Boiling Point: 481.7°C at 760 mmHg
  • Density: 1.122g/cm3
  • Refractive index: 1.579
  • Flash Point: 245.1°C
  • Molecular Weight: 281.34896
  • InchiKey: UWPBQLKEHGGKKD-GZTJUZNOSA-N
  • InChI: InChI=1S/C18H19NO2/c20-18(21)12-6-2-5-11-17(15-8-3-1-4-9-15)16-10-7-13-
    19-14-16/h1,3-4,7-11,13-14H,2,5-6,12H2,(H,20,21)/b17-11+
  • Molecular Formula: C18H19NO2
  • Molecular Structure:CAS No:89667-40-3 (E)-7-phenyl-7-pyridin-3-ylhept-6-enoic acid
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89667-40-3 ISBOGREL

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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89667-40-3 Isbogrel

  • Isbogrel, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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89667-40-3 Isbogrel

  • Isbogrel, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
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89667-40-3 Isbogrel

  • Isbogrel
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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References of (E)-7-phenyl-7-pyridin-3-ylhept-6-enoic acid
Title: Isbogrel
CAS Registry Number: 89667-40-3
CAS Name: (E)-7-Phenyl-7-(3-pyridinyl)-6-heptenoic acid
Manufacturers' Codes: CV-4151
Molecular Formula: C18H19NO2
Molecular Weight: 281.35
Percent Composition: C 76.84%, H 6.81%, N 4.98%, O 11.37%
Literature References: Thromboxane A2 (TXA2) synthetase inhibitor. Prepn: S. Terao, K. Nishikawa, EP 98690; eidem, US 4518602 (1984, 1985 both to Takeda); and inhibition of TXA2: K. Kato et al., J. Med. Chem. 28, 287 (1985). Pharmacology: Z. Terashita et al., Thromb. Res. 41, 223 (1986). Antithrombotic effect in experimental thrombi: T. Matsubara et al., Am. Heart J. 118, 837 (1989). Clinical pharmacokinetics: T. Kuzuya et al., Cardiovasc. Drugs Ther. 2, 693 (1988). Clinical trial: R. Hattori et al., Jpn. Circ. J. 55, 324 (1991).
Properties: mp 114-115°.
Melting point: mp 114-115°
Therap-Cat: Antithrombotic.
Keywords: Antithrombotic; Thromboxane A2-Sythetase Inhibitor.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.