Home > Name List By e > Ethanone,2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenyl-

CAS No 90-69-7 , Ethanone,2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenyl-

  • Name: Ethanone,2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenyl-
  • Synonyms: (-)-a-Lobeline; Lobelin;8,10-Diphenyllobelionol; Lobnico; L-Lobeline; NIH 11034; Lobeline (8CI);Ethanone,2-[6-(2-hydroxy-2-phenylethyl)-1-methyl-2-piperidinyl]-1-phenyl-, [2R-[2a,6a(S*)]]-; 2-[6-(b-Hydroxyphenethyl)-1-methyl-2-piperidyl]acetophenone; a-Lobeline (7CI); Inflatine;l-Lobeline; (-)-Lobeline;Ethanone,2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenyl-;
  • CAS Registry Number:
  • Flash Point: 247.5°C
  • Boiling Point: 485.6°C at 760 mmHg
  • Density: 1.085g/cm3
  • Refractive index: 1.562
  • Safety Statements: Poison by intraperitoneal and intravenous routes. Causes stimulation which leads to convulsions in severe cases. Nausea and vomiting are frequent. When heated to decomposition it emits toxic fumes of NOx.
  • Flash Point: 247.5°C
  • EINECS: 202-012-3
  • Molecular Weight: 337.46
  • InChI: InChI=1/C22H27NO2/c1-23-19(15-21(24)17-9-4-2-5-10-17)13-8-14-20(23)16-22(25)18-11-6-3-7-12-18/h2-7,9-12,19-21,24H,8,13-16H2,1H3
  • Molecular Formula: C22H27 N O2
  • Molecular Structure:CAS No:90-69-7 Ethanone,2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenyl-

Related products

Search by region :

Select to

90-69-7 Lobeline

  • IUPAC NAME-2-((2R,6S)-6-((S)-2-Hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethanone MOLECULAR FORMULA-C22H27NO2 MOLAR MASS-337.455 Lobeline is a natural alkaloid found in "Indian tobacco" "Devil's tobacco" "cardinal flower" "great lobelia"...
  • India Swapnroop Drugs & Pharmaceuticals [Manufacturer, Trading Company]
  • Tel: 91-240-6641875
  • Fax: 91-240-6641875
  • Address: Harsool Aurangabad,MaharashtraIndia
Contact Supplier

90-69-7 Ethanone,2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenyl-

  • China YiPeng Chemical [Manufacturers]
  • Tel: 571 85376369
  • Fax: 571 88233092
  • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China null,ZheJiangChina
Contact Supplier

90-69-7 Lobeline

Contact Supplier

90-69-7 LOBELIDINE 95%, 98%

  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
Contact Supplier

90-69-7 L-LOBELINE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
Contact Supplier

Select to

1/1
References of Ethanone,2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenyl-
Title: Lobeline
CAS Registry Number: 90-69-7
CAS Name: 2-[(2R,6S)-6-[(2S)-2-Hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenylethanone
Synonyms: 2-[6-(b-hydroxyphenethyl)-1-methyl-2-piperidyl]acetophenone; a-lobeline; inflatine
Molecular Formula: C22H27NO2
Molecular Weight: 337.46
Percent Composition: C 78.30%, H 8.06%, N 4.15%, O 9.48%
Literature References: High affinity nicotinic ligand. From herb and seeds of Lobelia inflata L., Lobeliaceae (Indian tobacco): H. Wieland, Ber. 54, 1784 (1921). Structure: H. Wieland, O. Dragendorff, Ann. 473, 83 (1929). Synthesis: H. Wieland, I. Drishaus, ibid. 102; G. Schering, L. Winterhalder, ibid. 126. Absolute configuration: Sch?pf, Müller, Ann. 687, 241 (1965). Pharmacology: M. I. Damaj et al., J. Pharmacol. Exp. Ther. 282, 410 (1997). Receptor binding study: D. Flammia et al., J. Med. Chem. 42, 3726 (1999). Comprehensive description: F. J. Muhtadi, Anal. Profiles Drug Subs. 19, 261-313 (1990). Review of mechanism of action and therapeutic potential in psychostimulant abuse: L. P. Dwoskin, P. A. Crooks, Biochem. Pharmacol. 63, 89-98 (2002).
Properties: Needles from alc, ether, benzene, mp 130-131°. [a]D15 -43° (alc). Very slightly sol in water or in petr ether; sol in hot alcohol, or in chloroform, benzene, ether.
Melting point: mp 130-131°
Optical Rotation: [a]D15 -43° (alc)
 
Derivative Type: Hydrochloride
CAS Registry Number: 134-63-4
Molecular Formula: C22H27NO2.HCl
Molecular Weight: 373.92
Percent Composition: C 70.67%, H 7.55%, N 3.75%, O 8.56%, Cl 9.48%
Properties: Rosettes of slender needles from alcohol, mp 178-180°. [a]D20 -43° (c = 2). uv max (methanol) 245, 280 nm (log e 4.08, 3.05). One gram dissolves in 40 ml water, 12 ml alcohol; very sol in chloroform; very slightly sol in ether. Water solns are slightly acid to litmus. A 1% soln in water has a pH of 4.0-6.0.
Melting point: mp 178-180°
Optical Rotation: [a]D20 -43° (c = 2)
Absorption maximum: uv max (methanol) 245, 280 nm (log e 4.08, 3.05)
 
Derivative Type: Sulfate
CAS Registry Number: 134-64-5
Molecular Formula: (C22H27NO2)2.H2SO4
Molecular Weight: 772.99
Percent Composition: C 68.37%, H 7.30%, N 3.62%, O 16.56%, S 4.15%
Properties: Hygroscopic. Crystals from alc. [a]D20 -25° (c = 2). Soluble in about 30 parts water, slightly in alcohol.
Optical Rotation: [a]D20 -25° (c = 2)
 
Derivative Type: (±)-Form
CAS Registry Number: 134-65-6
Synonyms: Lobelidine
Properties: Prisms, mp 110°.
Melting point: mp 110°
 
Therap-Cat: CNS stimulant.
Therap-Cat-Vet: Has been used as a respiratory stimulant, ruminatoric.
Keywords: Respiratory Stimulant; CNS Stimulant.