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CAS No 93413-69-5 , 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol

  • Name: 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol
  • Synonyms: Venlafaxinum [INN-Latin];1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol;Elafax; CHEBI:9943; Venlafaxina [INN-Spanish]; Venlafaxina; 93413-69-5; Venlafaxine [INN:BAN]; Venlafaxinum;
  • CAS Registry Number:
  • Density: 1.06 g/cm3
  • Refractive index: 1.579
  • Molecular Weight: 277.40178
  • InchiKey: PNVNVHUZROJLTJ-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-
    8-14/h7-10,16,19H,4-6,11-13H2,1-3H3
  • Molecular Formula: C17H27NO2
  • Molecular Structure:CAS No:93413-69-5 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol
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93413-69-5 Add to Wishlist ORDER FOR GOODS 1000000102018-01-18 05:57:27 1000000152018-01-19 07:43:14 1000000132018-01-19 03:24:18 1000000122018-01-18 07:03:07 1

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93413-69-5 VENLAFAXINE

  • Germany CHEMOS GmbH [Manufacturer]
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  • Address: CHEMOS GmbH
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93413-69-5 Venlafaxine

  • China Shanghai Synnad Chemical Co., Ltd. [Importer/Exporter]
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93413-69-5 Venlafaxine

  • IUPAC NAME-(RS)-1-[2-dimethylamino-1-(4-methoxyphenyl)-ethyl]cyclohexanol MOLECULAR FORMULA-C17H27NO2 MOLAR MASS-277.402 g/mol Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor class Venlafaxine is used primarily for...
  • India Swapnroop Drugs & Pharmaceuticals [Manufacturer, Trading Company]
  • Tel: 91-240-6641875
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  • Address: Harsool Aurangabad,MaharashtraIndia

93413-69-5 Venlafaxine

  • China YiPeng Chemical [Manufacturers]
  • Tel: 571 85376369
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  • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China ,ZheJiangChina
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93413-69-5 Venlafaxine

  • Venlafaxine CAS: 93413-69-5 English name: Venlafaxine Molecular formula: C17H27NO2 Molecular weight: 277.4 Properties: white or almost white crystalline Standard: Enterprise Standard Content: 98.5 to 101.0% Uses: Uses the same time inhibition of 5 - ...
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93413-69-5 Venlafaxine

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93413-69-5 Venlafaxine

  • China Kouting Chemical Co.,Ltd [Importer/Exporter]
  • Tel: +86-(21)-58116473
  • Fax: +86-(21)-61094103
  • Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318, shanghai,shanghaiChina
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93413-69-5 Venlafaxine

  • China shanghai sphchem co.,ltd [Manufacturers]
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  • Address: NO.133, Wuye, Yangxin Road ,Shanghai China shanghai,shanghai ChinaChina
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93413-69-5 Venlafaxine

  • China Simag Chemicals [Manufacturer]
  • Tel: +86 592 2680277
  • Fax: +86 592 2680237
  • Address: Simag Chemicals
    A-9D Atlantic sea view city,
    No.9 Hubin West Rd.,
    Xiamen China. ,China
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References of 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol
Title: Venlafaxine
CAS Registry Number: 93413-69-5
CAS Name: 1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol
Synonyms: (±)-1-[a-[(dimethylamino)methyl]-p-methoxybenzyl]cyclohexanol; N,N-dimethyl-2-(1-hydroxycyclohexyl)-2-(4-methoxyphenyl)ethylamine; venlafexine
Molecular Formula: C17H27NO2
Molecular Weight: 277.40
Percent Composition: C 73.61%, H 9.81%, N 5.05%, O 11.54%
Literature References: Serotonin noradrenaline reuptake inhibitor (SNRI). Prepn: G. E. M. Husbands et al., EP 112669; US 4535186 (1984, 1985 both to Am. Home Prods.); and resolution of isomers: J. P. Yardley et al., J. Med. Chem. 33, 2899 (1990). Receptor binding studies: E. A. Muth et al., Biochem. Pharmacol. 35, 4493 (1986). HPLC determn in biological fluids: D. R. Hicks et al., Ther. Drug Monit. 16, 100 (1994). Clinical pharmacokinetics: K. J. Klamerus et al., J. Clin. Pharmacol. 32, 716 (1992). Clinical trial in major depression: E. Schweizer et al., J. Clin. Psychopharmacol. 11, 233 (1991). Review of pharmacology and clinical efficacy in depression: S. A. Montgomery, J. Clin. Psychiatry 54, 119-126 (1993). Clinical trial in generalized anxiety disorder: A. J. Gelenberg et al., J. Am. Med. Assoc. 283, 3082 (2000).
 
Derivative Type: Hydrochloride
CAS Registry Number: 99300-78-4
Manufacturers' Codes: Wy-45030
Trademarks: Effexor (Wyeth)
Molecular Formula: C17H27NO2.HCl
Molecular Weight: 313.86
Percent Composition: C 65.06%, H 8.99%, N 4.46%, O 10.20%, Cl 11.30%
Properties: White to off-white crystalline solid from methanol/ethyl acetate, mp 215-217°. Soly (mg/ml): 572 water. Partition coefficient (octanol/water): 0.43.
Melting point: mp 215-217°
Log P: Partition coefficient (octanol/water): 0.43
 
Derivative Type: (+)-Form
Properties: Crystals from ethyl acetate, mp 102-104°. [a]D25 +27.6° (c = 1.07 in 95% ethanol).
Melting point: mp 102-104°
Optical Rotation: [a]D25 +27.6° (c = 1.07 in 95% ethanol)
 
Derivative Type: (+)-Form hydrochloride
Manufacturers' Codes: Wy-45655
Properties: Crystals from methanol/ether, mp 240-240.5°. [a]D25 -4.7° (c = 0.945 in ethanol).
Melting point: mp 240-240.5°
Optical Rotation: [a]D25 -4.7° (c = 0.945 in ethanol)
 
Derivative Type: (-)-Form
Properties: Crystals from ethyl acetate, mp 102-104°. [a]D25 -27.1° (c = 1.04 in 95% ethanol).
Melting point: mp 102-104°
Optical Rotation: [a]D25 -27.1° (c = 1.04 in 95% ethanol)
 
Derivative Type: (-)-Form hydrochloride
Manufacturers' Codes: Wy-45651
Properties: Crystals from methanol/ether, mp 240-240.5°. [a]D25 +4.6° (c = 1.0 in ethanol).
Melting point: mp 240-240.5°
Optical Rotation: [a]D25 +4.6° (c = 1.0 in ethanol)
 
Therap-Cat: Antidepressant.
Keywords: Antidepressant; Serotonin Noradrenaline Reuptake Inhibitor (SNRI).