Home > Name List By 4 > 4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]benzoic acid

CAS No 94497-51-5 , 4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]benzoic
acid

  • Name: 4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]benzoic
    acid
  • Synonyms: Tamibaro; Amnolake; retinobenzoic acid;4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]benzoic
    acid; Amnoleuk; 94497-51-5; Am80; Amnoid; CHEBI:32181;Am 80;
  • CAS Registry Number:
  • Flash Point: 225.7°C
  • Boiling Point: 449.6°Cat760mmHg
  • Density: 1.154g/cm3
  • Refractive index: 1.593
  • Flash Point: 225.7°C
  • Molecular Weight: 351.4388
  • InchiKey: MUTNCGKQJGXKEM-UHFFFAOYSA-N
  • InChI: InChI=1S/C22H25NO3/c1-21(2)11-12-22(3,
    4)18-13-16(9-10-17(18)21)23-19(24)14-5-7-15(8-6-14)20(25)26/h5-10,13H,
    11-12H2,1-4H3,(H,23,24)(H,25,26)
  • Molecular Formula: C22H25NO3
  • Molecular Structure:CAS No:94497-51-5 4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]benzoic<br />acid

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94497-51-5 Tamibarotene

  • China Hangzhou Sage Chemical Co., Ltd. [, Manufacturer]
  • Tel: +86-571-86818502
  • Fax: +86-571-86818503
  • Address: RM501 Tower A, New Youth Plaza, NO.8 Jia Shan Road, Hangzhou, Zhejiang 310014, ,ZhejiangChina
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94497-51-5 Tamibarotene

  • China Watson International Ltd. []
  • Tel: +86-(512)-55117610
  • Fax: +86-(512)-55117630
  • Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332, ,China
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94497-51-5 Tamibarotene

  • China Kouting Chemical Co.,Ltd [Importer/Exporter]
  • Tel: +86-(21)-58116473
  • Fax: +86-(21)-61094103
  • Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318, shanghai,shanghaiChina
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94497-51-5 Tamibarotene

  • China shanghai sphchem co.,ltd [Manufacturers]
  • Tel: +86-21-56491756 13512199871
  • Fax: 0
  • Address: NO.133, Wuye, Yangxin Road ,Shanghai China shanghai,shanghai ChinaChina
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94497-51-5 Tamibarotene

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94497-51-5 Tamibarotene

  • China Maple Chemical Co.,ltd. [Manufacturer]
  • Tel: 86-574- 87512300
  • Fax: 86-574-82095182
  • Address: No.347,Sanbei Road,Sanbei Town,Cixi ,Zhejiang,China Ningbo,ZhejiangChina
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94497-51-5 Tamibarotene

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94497-51-5 Tamibarotene

  • China Yongyi Biotechnology Co,.Ltd [Importer/Exporter]
  • Tel: +86-21-60904639
  • Fax: +86-21-60904609
  • Address: Suite 3005, City Gateway, No.398 North CaoXi Road, XuHui District, Shanghai 200030, China. ,China
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94497-51-5 Tamibarotene

  • China Model-chemical co., LTD [Manufacturers]
  • Tel: +86-021-65432178
  • Fax: +86-021-65432178
  • Address: shanghai shanghai,shanghaiChina
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94497-51-5 Tamibarotene

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References of 4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]benzoic
acid
Title: Tamibarotene
CAS Registry Number: 94497-51-5
CAS Name: 4-[[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)amino]carbonyl]benzoic acid
Synonyms: p-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthylcarbamoyl)benzoic acid
Manufacturers' Codes: AM-80
Trademarks: Tamibaro (Toko)
Molecular Formula: C22H25NO3
Molecular Weight: 351.44
Percent Composition: C 75.19%, H 7.17%, N 3.99%, O 13.66%
Literature References: Synthetic retinoic acid receptor-a/b-selective retinoid. Prepn: K. Shudo, EP 170105 (1986 to Sumitomo; Yoshitomi); idem, US 4703110 (1987); H. Kagechika et al., J. Med. Chem. 31, 2182 (1988). HPLC determn in plasma: M. Itoh, G. Kominami, J. Immunoassay Immunochem. 22, 213 (2001). Receptor binding studies in human leukemia cells: Y. Hashimoto et al., Jpn. J. Cancer Res. 79, 473 (1988). Series of articles on pharmacokinetics and reproductive and developmental toxicity: K. Mizojiri et al., Arzneim.-Forsch. 47, 59, 195, 201, 259, 270 (1997). Inhibition of myeloma cell-induced angiogeneis: T. Sanda et al., Leukemia 19, 901 (2005). Clinical evaluation in acute promyelocytic leukemia: K. Shinjo et al., Int. J. Hematol. 72, 470 (2000).
Properties: Colorless prisms from ethyl acetate-n-hexane, mp 231-232°.
Melting point: mp 231-232°
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Retinoids and Analogs.