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CAS No 959-10-4 , 2-(4-phenylphenyl)butanoic acid

  • Name: 2-(4-phenylphenyl)butanoic acid
  • Synonyms: 4-Biphenylylethylacetic acid; Maggioni 1559; Liposana; 4-Diphenylylethylacetic acid; Ethyl-p-xenylacetic acid;Liosol;2-(4-phenylphenyl)butanoic acid;
  • CAS Registry Number:
  • Flash Point: 296.9°C
  • Boiling Point: 400.1°C at 760 mmHg
  • Density: 1.112g/cm3
  • Refractive index: 1.573
  • Flash Point: 296.9°C
  • EINECS: 213-492-9
  • Molecular Weight: 240.29704
  • InchiKey: IYEPZNKOJZOGJG-UHFFFAOYSA-N
  • InChI: InChI=1S/C16H16O2/c1-2-15(16(17)18)14-10-8-13(9-11-14)12-6-4-3-5-7-12/
    h3-11,15H,2H2,1H3,(H,17,18)
  • Molecular Formula: C16H16O2
  • Molecular Structure:CAS No:959-10-4 2-(4-phenylphenyl)butanoic acid

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References of 2-(4-phenylphenyl)butanoic acid
Title: Xenbucin
CAS Registry Number: 959-10-4
CAS Name: a-Ethyl-[1,1￠-biphenyl]-4-acetic acid
Synonyms: 2-(4-biphenylyl)butyric acid; a-(4-biphenylyl)butyric acid; a-(4-diphenylyl)butyric acid; a-(p-xenyl)butyric acid; 4-diphenylylethylacetic acid; 4-biphenylylethylacetic acid; ethyl-p-xenylacetic acid; a-ethyl-p-phenyl-a-toluic acid
Manufacturers' Codes: MG-1559
Trademarks: Liosol (Maggioni)
Molecular Formula: C16H16O2
Molecular Weight: 240.30
Percent Composition: C 79.97%, H 6.71%, O 13.32%
Literature References: Prepn: Blicke, Grier, J. Am. Chem. Soc. 65, 1725 (1943); Cavallini, Massarani, Farmaco Ed. Sci. 11, 167 (1956). Fibrinolytic activity: R. J. Gryglewski, M. Eckstein, Nature 214, 626 (1967).
Properties: Crystals from glacial acetic acid, mp 123-125°. Soluble in ethanol, methanol, acetone, carbon tetrachloride, benzene, ether, dimethylformamide. Practically insol in water.
Melting point: mp 123-125°
 
Derivative Type: trans-4-Phenylcyclohexylamine salt (1:1)
CAS Registry Number: 19992-80-4
Synonyms: Butixirate
Manufacturers' Codes: MG-5771
Trademarks: Flectar (Maggioni)
Molecular Formula: C28H33NO2
Molecular Weight: 415.57
Percent Composition: C 80.92%, H 8.00%, N 3.37%, O 7.70%
Literature References: Prepn, analgesic and anti-inflammatory properties: G. Cantarelli et al., Farmaco Ed. Sci. 24, 140 (1969); GB 1168542 (1969 to Maggioni), C.A. 72, 43197 (1970). Therapeutic effectiveness: P. Croce, Clin. Ter. 50, 241 (1969).
Properties: Crystals, mp 224-227°. LD50 i.p. in mice: 183 mM/kg (Cantarelli).
Melting point: mp 224-227°
Toxicity data: LD50 i.p. in mice: 183 mM/kg (Cantarelli)
 
Therap-Cat: Free acid as antilipemic; trans-4-phenylcyclohexylamine salt as analgesic, anti-inflammatory.
Keywords: Antilipemic.