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CAS No 972-02-1 , 1,1-diphenyl-4-piperidin-1-ylbutan-1-ol

  • Name: 1,1-diphenyl-4-piperidin-1-ylbutan-1-ol
  • Synonyms: defenidol; Cephadol; Difenidolum [INN-Latin]; Vontrol; DIPHENIDOL;Difenidol; Difenidolum;1,1-diphenyl-4-piperidin-1-ylbutan-1-ol; Nometic; Difenidolo [DCIT]; Avomol;
  • CAS Registry Number:
  • Melting Point: 105
  • Density: 1.066 g/cm3
  • Safety Statements: Poison by intravenous and subcutaneous routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx.
  • EINECS: 213-540-9
  • Molecular Weight: 309.44518
  • InchiKey: OGAKLTJNUQRZJU-UHFFFAOYSA-N
  • InChI: InChI=1S/C21H27NO/c23-21(19-11-4-1-5-12-19,
    20-13-6-2-7-14-20)15-10-18-22-16-8-3-9-17-22/h1-2,4-7,11-14,23H,3,8-10,
    15-18H2
  • Molecular Formula: C21H27NO
  • Molecular Structure:CAS No:972-02-1 1,1-diphenyl-4-piperidin-1-ylbutan-1-ol
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972-02-1 difenidol

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi null,ShanXiChina
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972-02-1 Picartamide

  • Picartamide, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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972-02-1 Difenidol

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972-02-1 Diphenidol HCI

  • China Watson International Ltd. null
  • Tel: +86-(512)-55117610
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  • Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332, null,nullChina
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972-02-1 Picartamide, 99%

  • Picartamide, 99%
  • China Pleapharma Co.,Ltd [Manufacturer]
  • Tel: 86 23 67030808
  • Fax: 86 23 67030809
  • Address: 22F,Jingxin center,No.70 Xingguang Road,Yubei Zone,Chongqing402232 chongqingCHINA chongqing,nullChina
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972-02-1 Diphenidol HCI

  • United States Alfa Chem null
  • Tel: +1-(516)-504-0059, 800-375-6869
  • Fax: +1-(516)-504-0039
  • Address: 2 Harbor Way, Kings Point, New York 11024, null,nullUnited States
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972-02-1 Diphenidol HCI

  • United States Parchem Trading [Manufacturer]
  • Tel: 914.654.6800
  • Fax: 914.654.6899
  • Address: Parchem Trading Ltd.
    415 Huguenot Street
    New Rochelle, NY 10801 null,nullUnited States
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972-02-1 DIFENIDOL

  • China HANGZHOU THINK CHEMICAL CO. [Manufacturer]
  • Tel: +86-571-81956191/ +86-571-81956192
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  • Address: 425 MOGAN HILL ROAD ,
    HANGZHOU, 310011 CHINA null,nullChina
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972-02-1 DIFENIDOL

  • China SINOCO CHEMICAL CO., LIMITED [Importer/Exporter]
  • Tel: +86-571-81956191, 81956192
  • Fax: 86-571-81956190 88386326
  • Address: 425 Ruiqi Mansion Moganshan Road , Hangzhou 310011 China. Hangzhou,ZhejiangChina
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972-02-1 DIFENIDOL

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References of 1,1-diphenyl-4-piperidin-1-ylbutan-1-ol
Title: Diphenidol
CAS Registry Number: 972-02-1
CAS Name: a,a-Diphenyl-1-piperidinebutanol
Synonyms: 1,1-diphenyl-4-piperidino-1-butanol; diphenyl-[3-(1-piperidyl)propyl]carbinol; defenidol
Manufacturers' Codes: SKF-478
Molecular Formula: C21H27NO
Molecular Weight: 309.45
Percent Composition: C 81.51%, H 8.79%, N 4.53%, O 5.17%
Literature References: Prepn: Miescher, Marxer, US 2411664 (1946 to Ciba); Barrett, Wilkinson, GB 683950 (1952 to Wellcome Foundation), C.A. 48, 2112e (1954). Structure-activity studies: Gautier et al., Med. Pharmacol. Exp. 13, 325 (1965). Clinical studies: Cutt et al., Aerosp. Med. 39, 682 (1968); Benson, ibid. 40, 589 (1969). Acute toxicity: E. I. Goldenthal, Toxicol. Appl. Pharmacol. 18, 185 (1971).
Properties: Needles from petr ether, mp 104-105°. LD50 s.c. in rats: 50 mg/kg (Goldenthal).
Melting point: mp 104-105°
Toxicity data: LD50 s.c. in rats: 50 mg/kg (Goldenthal)
 
Derivative Type: Hydrochloride
CAS Registry Number: 3254-89-5
Manufacturers' Codes: SKF-478-A
Trademarks: Ansmin (SS Pharm.); Cefadol (Nippon Shinyaku); Celmidol (Tobishi); Difenidolin (Taiyo); Maniol (Morishita); Mecalmin (Yoshitomi); Pineroro (Maruko); Satanolon (Tatsumi); Tenesdol (Hishiyama); Vontrol (SK & F); Wansar (Hoei)
Molecular Formula: C21H27NO.HCl
Molecular Weight: 345.91
Percent Composition: C 72.92%, H 8.16%, N 4.05%, O 4.63%, Cl 10.25%
Properties: Crystals from chloroform + ethyl acetate, mp 212-214°. Freely sol in methanol; sol in water, chloroform. Practically insol in ether, benzene, petr ether.
Melting point: mp 212-214°
 
Therap-Cat: Antiemetic.
Keywords: Antiemetic.