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CAS No 98105-99-8 , 6-fluoro-1-(4-fluorophenyl)-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic
acid

  • Name: 6-fluoro-1-(4-fluorophenyl)-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic
    acid
  • Synonyms: Abbott 57135; Difloxacino [Spanish]; Sarafloxacin [INN:BAN];98105-99-8; Difloxacinum [Latin];6-fluoro-1-(4-fluorophenyl)-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic
    acid; Difloxacine [French];
  • CAS Registry Number:
  • Density: 1.436 g/cm3
  • Refractive index: 1.633
  • Molecular Weight: 385.364086
  • InchiKey: XBHBWNFJWIASRO-UHFFFAOYSA-N
  • InChI: InChI=1S/C20H17F2N3O3/c21-12-1-3-13(4-2-12)25-11-15(20(27)28)19(26)14-9-
    16(22)18(10-17(14)25)24-7-5-23-6-8-24/h1-4,9-11,23H,5-8H2,(H,27,28)
  • Molecular Formula: C20H17F2N3O3
  • Molecular Structure:CAS No:98105-99-8 6-fluoro-1-(4-fluorophenyl)-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic<br />acid
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98105-99-8 3-Quinolinecarboxylicacid, 6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi null,ShanXiChina
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98105-99-8 3-Quinolinecarboxylicacid, 6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-

  • United States HBCChem, Inc. [Manufacturers]
  • Tel: +1-510-219-6317
  • Fax: +1-510-675-0318
  • Address: null Union City,CaliforniaUnited States
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98105-99-8 SARAFLOXACIN

  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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98105-99-8 Sarafloxacin

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98105-99-8 Sarafloxacin

  • Sarafloxacin B150841 98105-99-8
  • China bepharm ltd. null
  • Tel: 86-21-51816456
  • Address: 128 Xiangyin Road, Room C320-321 Yangpu District, Shanghai 200433, China null,nullChina
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98105-99-8 Sarafloxacin

  • China TaiZhou HiKong Chemical Co., Ltd. null
  • Tel: +86-18967213045,13957694715
  • Fax: +86-(580)-6033180,6034626
  • Address: Taizhou Economic Technical Development Zone, Taizhou, Zhejiang 318000, null,nullChina
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98105-99-8 Sarafloxacin

  • United States Tecoland Corporation null
  • Tel: +1-(732)-603-9577
  • Fax: +1-(732)-906-1522
  • Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428, null,nullUnited States
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98105-99-8 3-Quinolinecarboxylicacid, 6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-

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98105-99-8 3-Quinolinecarboxylicacid, 6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-

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References of 6-fluoro-1-(4-fluorophenyl)-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic
acid
Title: Sarafloxacin
CAS Registry Number: 98105-99-8
CAS Name: 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
Molecular Formula: C20H17F2N3O3
Molecular Weight: 385.36
Percent Composition: C 62.33%, H 4.45%, F 9.86%, N 10.90%, O 12.46%
Literature References: Fluorinated quinolone antibacterial. Prepn: D. T. W. Chu, EP 131839; idem, US 4730000 (1985, 1988 both to Abbott); D. T. W. Chu et al., J. Med. Chem. 28, 1558 (1985); H. Narita et al., JP Kokai 85 237069 (1985 to Toyama). Comparative in vitro antibacterial spectrum: A. Digranes, W. L. Dibb, Chemotherapy 34, 298 (1988). In vivo antibacterial activity: P. B. Fernandes et al., Antimicrob. Agents Chemother. 29, 201 (1986). HPLC determn: J. F. Bauer et al., Pharm. Res. 7, 1177 (1990).
 
Derivative Type: Monohydrochloride
CAS Registry Number: 91296-87-6
Manufacturers' Codes: Abbott 56620; A-56620
Molecular Formula: C20H17F2N3O3.HCl
Molecular Weight: 421.83
Percent Composition: C 56.95%, H 4.30%, F 9.01%, N 9.96%, O 11.38%, Cl 8.40%
Properties: mp as monohydrate >275°.
Melting point: mp as monohydrate >275°
 
Therap-Cat-Vet: Antibacterial.