ChemScene, LLC

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  • Company Name: ChemScene, LLC
  • Street: 11 Deer Park Drive, Suite 102D Monmouth Junction, NJ 08852
  • City: Monmouth Junction
  • Province/state: New Jersey
  • Country/region: United States
  • Contact Person: Ms.James Gao
  • Tel: 732-484-9848
  • Fax: --
  • Email:

PF-3758309

    Detailed Description

    PF-3758309 is an orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity. PAK4 inhibitor PF-3758309 binds to PAK4, inhibiting PAK4 activity and cancer cell growth. PAK4, a serine/threonine kinase belonging to the p21-activated kinase (PAK) family, is often upregulated in a variety of cancer cell types and plays an important role in cancer cell motility, proliferation, and survival.

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