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Odanacatib;MK-0822;MK 0822;MK0822

  • CAS No:603139-19-1 (2S)-N-(1-cyanocyclopropyl)-4-fluoro-4-methyl-2-[[(1S)-2,2,<br />2-trifluoro-1-[4-(4-methylsulfonylphenyl)phenyl]ethyl]amino]pentanamide
    Molecular Structure

    Detailed Description

    Odanacatib (MK 0822) is an inhibitor of cathepsin K with potential anti-osteoporotic activity. Odanacatib selectively binds to and inhibits the activity of cathepsin K (IC50=0.2nM), which may result in a reduction in bone resorption, improvement of bone mineral density, and a reversal in osteoporotic changes. Odanacatib is currently in clinical development for the treatment of postmenopausal osteoporosis

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